TIAM1

Rho guanine nucleotide exchange factor TIAM1 · Q13009 · TIAM1 on Sugi Atlas →

0 patent compounds predicted against TIAM1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TIAM1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Sorafenib Tosylate and Bevacizumab in Treating Patients With Advanced Kidney Cancer PHASE1/PHASE2COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas PHASE1/PHASE2COMPLETED
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma PHASE1/PHASE2RECRUITING
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Interest of PHARMaceutical Conciliation to Understand Drug Interactions, Phytotherapy, and Targeted Therapies in Chronic Myeloid Leukemia nanRECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Gene Expression in Patients With Epiretinal Membranes nanUNKNOWN
Genomic Landscape of Intramedullary Astrocytoma nanUNKNOWN
Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA nanRECRUITING
Gene-expression Profiles in CNS-metastatic Non-small Cell Lung Cancer nanUNKNOWN
Studying the Role of Circulating Tumor Cell Clusters in Patients With High-risk Early Breast Cancer, Study GALIA nanRECRUITING
Susceptibility Genes in Autism Spectrum Disorders nanCOMPLETED
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development nanCOMPLETED
Expression of CD19 Complex in Lymphoproliferative Disorders nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Markers in the Diagnosis of TIA nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart nanUNKNOWN
Diagnostic and Prognostic Value of MicroRNA in Breast Cancer Patients nanUNKNOWN
The Etiology and Progression of Brain Tumors nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TIAM1 binder may also engage these)

ProteinNameSimilarity
Q60610 1.000 Q60610 →
Q6DN90 1.000 Q6DN90 →
O08774 1.000 O08774 →
Q8C115 1.000 Q8C115 →
Q9H329 1.000 Q9H329 →
Q9D3S3 1.000 Q9D3S3 →
Q64512 0.999 Q64512 →
Q6I6G8 0.999 Q6I6G8 →
A7MBB4 0.999 A7MBB4 →
Q9DDT2 0.999 Q9DDT2 →
Q9D684 0.998 Q9D684 →
Q9ERE6 0.998 Q9ERE6 →
O94885 0.998 O94885 →
Q5SW75 0.998 Q5SW75 →
Q6IVY4 0.998 Q6IVY4 →
Q3UMB5 0.997 Q3UMB5 →
Q8N103 0.997 Q8N103 →
Q9FY74 0.997 Q9FY74 →
E7F568 0.997 E7F568 →
Q8C1B1 0.997 Q8C1B1 →
Q6ZMN7 0.997 Q6ZMN7 →
Q9HCH5 0.997 Q9HCH5 →
Q5RJW5 0.997 Q5RJW5 →
Q90YL3 0.997 Q90YL3 →
G3X9J0 0.997 G3X9J0 →
Q3UJB9 0.997 Q3UJB9 →
Q96PX1 0.997 Q96PX1 →
E9Q9W7 0.997 E9Q9W7 →
O14490 0.997 O14490 →
Q5T9C2 0.997 Q5T9C2 →