TMBIM6

Bax inhibitor 1 · P55061 · TMBIM6 on Sugi Atlas →

0 patent compounds predicted against TMBIM6, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TMBIM6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer PHASE4UNKNOWN
Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemia PHASE3COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Sorafenib Tosylate and Bevacizumab in Treating Patients With Advanced Kidney Cancer PHASE1/PHASE2COMPLETED
Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC PHASE2NOT_YET_RECRUITING
In Vivo Lithium Treatment Effects on Gene Expression Levels in Lymphoblastoid Cell Lines From Human Healthy Subjects PHASE1COMPLETED
A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours PHASE1COMPLETED
FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma PHASE1WITHDRAWN
A Phase I Study Of Thymoglobulin In Patients With Relapsed Or Refractory Multiple Myeloma PHASE1COMPLETED
Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE PHASE1RECRUITING
A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme PHASE1COMPLETED
Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme PHASE1COMPLETED
The Effect of TRA-8 on Ovarian Cancer Tissue nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Genetic Determinants of Sudden Cardiac Death nanCOMPLETED
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Impact of CASP3 Gene in Chemoresistance nanNOT_YET_RECRUITING
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA nanRECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Dietary Intervention With High Phenolic EVOO in CLL nanCOMPLETED
IVF Outcome in Polycystic Ovary Syndrome Patients nanUNKNOWN
Detection of Human Beta Cell Death in Type 1 Diabetes Mellitus (T1DM) by Methylation Specific Polymerase Chain Reaction (PCR) nanCOMPLETED
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Ex Vivo Evaluation of the Interest of the Association of Platinum With a Molecule BH3-mimetic ABT-737 in Samples of Ovarian Tumors nanCOMPLETED
Studying Cells Collected Through Ductal Lavage in Women Undergoing Surgery for Ductal Carcinoma In Situ or Other Breast Cancer nanCOMPLETED
Circulating Markers for Ischemic Heart Disease nanRECRUITING
Evaluation of CEMIP in Pancreatic Cancer nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a TMBIM6 binder may also engage these)

ProteinNameSimilarity
Q0V882 1.000 Q0V882 →
Q66RM2 1.000 Q66RM2 →
Q5R7R1 1.000 Q5R7R1 →
Q9D2C7 1.000 Q9D2C7 →
P55062 0.997 P55062 →
Q9VSH3 0.996 Q9VSH3 →
Q9LD45 0.993 Q9LD45 →
Q9IA79 0.993 Q9IA79 →
Q9MBD8 0.991 Q9MBD8 →
Q9SA63 0.984 Q9SA63 →
P0AAC7 0.984 P0AAC7 →
Q94A20 0.984 Q94A20 →
Q9PIQ8 0.983 Q9PIQ8 →
Q9CNM5 0.983 Q9CNM5 →
P44477 0.983 P44477 →
Q9ZQX7 0.983 Q9ZQX7 →
Q9CEU8 0.982 Q9CEU8 →
O74888 0.982 O74888 →
P0AAC6 0.982 P0AAC6 →
F4JIE8 0.982 F4JIE8 →
O31539 0.982 O31539 →
Q9HC24 0.981 Q9HC24 →
P63701 0.981 P63701 →
P0AAC4 0.980 P0AAC4 →
Q9ZKT1 0.979 Q9ZKT1 →
P0DA10 0.979 P0DA10 →
Q9DA39 0.979 Q9DA39 →
Q9A2A3 0.979 Q9A2A3 →
Q9M1V9 0.978 Q9M1V9 →
P0AAC5 0.978 P0AAC5 →