TMEM164 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TMEM164 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Pharmacogenomic Evaluation of Antihypertensive Responses	PHASE4	COMPLETED
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy	PHASE2	RECRUITING
Brain P-gp and Inflammation in People With Epilepsy	nan	COMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Genetic Study of Age-Related Macular Degeneration	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis	nan	COMPLETED
Markers and Mechanisms of Macrovascular Disease in IDDM	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
Primary Ciliary Dyskinesia in Adult Bronchiectasis	nan	NOT_YET_RECRUITING
Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.	nan	COMPLETED
Seven Year Update of Macular Degeneration Patients	nan	COMPLETED
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome	nan	RECRUITING
Role of TMEM219 Marker in Type 1 Diabetes	nan	UNKNOWN
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
Phenotypic and Genotypic Studies in Congenital and Early Onset Ataxias	nan	COMPLETED
Genetic Determinants of Sudden Cardiac Death	nan	COMPLETED
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services	nan	UNKNOWN
The Natural History of TRPV4 Neuropathy	nan	RECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Energy Balance and Weight Gain With Ivacaftor Treatment	nan	COMPLETED
Renal Transporters After Renal Transplantation	nan	UNKNOWN
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia	nan	RECRUITING
Family Blood Pressure Program - HyperGEN	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study	nan	RECRUITING
Evaluation of CEMIP in Pancreatic Cancer	nan	UNKNOWN
Genetic Characterization of Parkinson's Disease	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TMEM164 binder may also engage these)

Protein	Name	Similarity
Q6PHN7	—	0.987	Q6PHN7 →
Q9D8B1	—	0.964	Q9D8B1 →
Q9NVV5	—	0.964	Q9NVV5 →
Q8N6M3	—	0.951	Q8N6M3 →
Q05B45	—	0.950	Q05B45 →
TMEM120A	Transmembrane protein 120A	0.949	landscape →
Q8C1E7	—	0.949	Q8C1E7 →
Q5H8A4	—	0.947	Q5H8A4 →
B2LYG4	—	0.946	B2LYG4 →
A4IFN5	—	0.944	A4IFN5 →
Q5HZE2	—	0.943	Q5HZE2 →
Q8NBT3	—	0.943	Q8NBT3 →
P59266	—	0.943	P59266 →
Q9EPL4	—	0.942	Q9EPL4 →
Q86WK9	—	0.940	Q86WK9 →
Q865K8	—	0.939	Q865K8 →
Q0VCJ8	—	0.938	Q0VCJ8 →
Q8VDI9	—	0.938	Q8VDI9 →
Q9H1A3	—	0.937	Q9H1A3 →
Q8BWB6	—	0.936	Q8BWB6 →
Q2TA01	—	0.934	Q2TA01 →
Q5ZMH6	—	0.934	Q5ZMH6 →
A6NI61	—	0.933	A6NI61 →
Q9D1N4	—	0.932	Q9D1N4 →
Q5RBJ7	—	0.931	Q5RBJ7 →
Q6NXT6	—	0.930	Q6NXT6 →
Q9BZW5	—	0.930	Q9BZW5 →
B6ID01	—	0.929	B6ID01 →
Q6TCH4	—	0.929	Q6TCH4 →
Q4VBD2	—	0.929	Q4VBD2 →