Sugi Predict

Sugi Predict / Targets / TMX1

TMX1

Thioredoxin-related transmembrane protein 1 · Q9H3N1 · TMX1 on Sugi Atlas →

0 patent compounds predicted against TMX1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TMX1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy PHASE2ACTIVE_NOT_RECRUITING
Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer PHASE1/PHASE2WITHDRAWN
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer PHASE1/PHASE2SUSPENDED
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Pathogenetic Basis of Aortopathy and Aortic Valve Disease nanACTIVE_NOT_RECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Baseline Physiology Studies in Carriers of Gene Variant X Conferring Major Risk of CVD-prone Metabolic Disorders nanCOMPLETED
Tecfidera Diffusion Tensor Imaging nanCOMPLETED
TL1A Expression in Psoriatic Skin nanUNKNOWN
SEXI: Sciatic Expression and Identification of Differential Proteins in Traumatized Versus Nontraumatized Nerves nanUNKNOWN
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Epidemiology of Atherosclerosis nanCOMPLETED
Genetic Study of Age-Related Macular Degeneration nanCOMPLETED
Thermogenic Silencer Regulatory Factors in Humans nanACTIVE_NOT_RECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
IVF Outcome in Polycystic Ovary Syndrome Patients nanUNKNOWN
Thiol/Disulphide Homeostasis in Unexplained Infertility nanCOMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
Identification of Genetic Causes of Calcific Aortic Valve Disease nanACTIVE_NOT_RECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING
Effects of Preoperative Oral Carbohydrate Loading on Maternal Thiol-disulfide Homeostasis nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Renal Transporters After Renal Transplantation nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TMX1 binder may also engage these)

ProteinNameSimilarity
Q8VBT0 — 1.000 Q8VBT0 →
Q0Z7W6 — 0.999 Q0Z7W6 →
Q8C0L0 — 0.978 Q8C0L0 →
Q9H1E5 — 0.975 Q9H1E5 →
ANTXR2 Anthrax toxin receptor 2 0.975 landscape →
Q6IUU3 — 0.974 Q6IUU3 →
Q1JQC5 — 0.974 Q1JQC5 →
Q6NZZ3 — 0.972 Q6NZZ3 →
Q6DN12 — 0.971 Q6DN12 →
Q5EAU9 — 0.971 Q5EAU9 →
Q07DZ7 — 0.970 Q07DZ7 →
H2N4I1 — 0.970 H2N4I1 →
Q7TQ95 — 0.970 Q7TQ95 →
Q9EQY0 — 0.970 Q9EQY0 →
Q95KA5 — 0.970 Q95KA5 →
Q5R8E4 — 0.970 Q5R8E4 →
Q91WD0 — 0.970 Q91WD0 →
Q09YK6 — 0.969 Q09YK6 →
A8WG88 — 0.969 A8WG88 →
Q07E17 — 0.969 Q07E17 →
Q66H15 — 0.969 Q66H15 →
Q6DFX2 — 0.969 Q6DFX2 →
Q8BND5 — 0.969 Q8BND5 →
A2A6C4 — 0.969 A2A6C4 →
O70367 — 0.968 O70367 →
Q15061 — 0.968 Q15061 →
Q80ZD7 — 0.968 Q80ZD7 →
Q5DJV7 — 0.968 Q5DJV7 →
Q9NPR9 — 0.968 Q9NPR9 →
Q8BMF8 — 0.968 Q8BMF8 →