TNKS1BP1

182 kDa tankyrase-1-binding protein · Q9C0C2 · TNKS1BP1 on Sugi Atlas →

0 patent compounds predicted against TNKS1BP1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TNKS1BP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety PHASE2COMPLETED
IMA910 Plus GM-CSF With Low-dose Cyclophosphamide Pre-treatment in Advanced Colorectal Carcinoma Patients Following a Successful 12 Week First-line Treatment With Oxaliplatin-based Chemotherapy (IMA910-101) PHASE1/PHASE2COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma PHASE2COMPLETED
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors PHASE1COMPLETED
Study of BCMA/CD70 CAR-T Therapy for Refractory cSLE PHASE1RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma PHASE1COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain nanCOMPLETED
NTRK 1,2,3 Rearrangements in Patients With Solid Tumors nanACTIVE_NOT_RECRUITING
The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human nanUNKNOWN
The Etiology and Progression of Brain Tumors nanCOMPLETED
A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib nanCOMPLETED
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders nanRECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease nanCOMPLETED
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma nanUNKNOWN
Novel Biomarkers in Inflammatory Bowel Disease nanCOMPLETED
Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion nanRECRUITING
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
National Study on Autism Spectrum Disorder in China nanCOMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Familial Investigations of Childhood Cancer Predisposition nanRECRUITING
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
ADAR1 Expression Level in Rectal Cancer nanRECRUITING
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Prognostic Biomarkers in Patients With Urothelial Carcinoma nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TNKS1BP1 binder may also engage these)

ProteinNameSimilarity
P58871 0.999 P58871 →
Q9HCH0 0.991 Q9HCH0 →
Q8N1P7 0.991 Q8N1P7 →
Q5JPB2 0.990 Q5JPB2 →
Q5YCW1 0.989 Q5YCW1 →
Q5VV67 0.989 Q5VV67 →
B7ZNG4 0.988 B7ZNG4 →
P0C671 0.988 P0C671 →
Q5S6V2 0.988 Q5S6V2 →
O88737 0.988 O88737 →
Q5YCW0 0.987 Q5YCW0 →
MAPT Microtubule-associated protein tau 0.987 landscape →
Q96L96 0.986 Q96L96 →
Q6PAC4 0.986 Q6PAC4 →
Q5YCV9 0.986 Q5YCV9 →
Q8NHY3 0.985 Q8NHY3 →
A6X8Z5 0.985 A6X8Z5 →
A8MYA2 0.985 A8MYA2 →
Q6GQX2 0.985 Q6GQX2 →
Q0GGX2 0.985 Q0GGX2 →
Q9JL04 0.985 Q9JL04 →
Q6NS69 0.985 Q6NS69 →
E7EW31 0.985 E7EW31 →
TET3 Methylcytosine dioxygenase TET3 0.985 landscape →
A6NGG8 0.985 A6NGG8 →
P19332 0.984 P19332 →
D3ZAQ5 0.984 D3ZAQ5 →
Q924C5 0.984 Q924C5 →
Q8K0T0 0.984 Q8K0T0 →
Q9H0D2 0.984 Q9H0D2 →