TPM4

Tropomyosin alpha-4 chain · P67936 · TPM4 on Sugi Atlas →

0 patent compounds predicted against TPM4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TPM4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem PHASE2/PHASE3COMPLETED
A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1 PHASE1/PHASE2RECRUITING
Rosuvastatin to Decrease Residual Immune Activation in HIV Infection PHASE2UNKNOWN
Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations nanUNKNOWN
Study of Muscle Abnormalities in Patients With Specific Genetic Mutations nanCOMPLETED
Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy nanUNKNOWN
Clinical Outcome Study for Dysferlinopathy nanUNKNOWN
A Multicenter Phenotype-Genotype Analysis of LGMD Patients in China nanENROLLING_BY_INVITATION
Cardiac Injury With Convulsive Status Epilepticus nanUNKNOWN
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level nanENROLLING_BY_INVITATION
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill nanUNKNOWN
Newborn Screening for Spinal Muscular Atrophy nanCOMPLETED
Characteristics of Nondystrophic Myotonias nanCOMPLETED
A Retrospective Study to Determine the Incidence of NTRK Fusions. NTRK Study nanCOMPLETED
Natural History Study for Patients With Nemaline Myopathy in Belgium nanNOT_YET_RECRUITING
Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease nanCOMPLETED
Registry of Unexplained Cardiac Arrest nanCOMPLETED
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
Brain as a Therapeutic and Research Target in Trigeminal Neuropathic Pain nanCOMPLETED
COronary Microcirculation and Troponin Elevation in Septic Shock nanCOMPLETED
The Prevalence of RYR1-related Disease nanNOT_YET_RECRUITING
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies. nanRECRUITING
MYO-SHARE: MYO-MRI in Neuromuscular Diseases nanENROLLING_BY_INVITATION
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development nanCOMPLETED
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies nanRECRUITING
A Prospective Pilot Study to Evaluate a New Marker of Ischemia in Chest Pain Triage nanCOMPLETED
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
Role of Ultrasound in Diagnosis of Muscle Diseases nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TPM4 binder may also engage these)

ProteinNameSimilarity
P67937 1.000 P67937 →
P09495 1.000 P09495 →
Q6IRU2 1.000 Q6IRU2 →
P02561 1.000 P02561 →
P07951 1.000 P07951 →
P42637 1.000 P42637 →
Q26519 1.000 Q26519 →
P13104 1.000 P13104 →
P0DSM6 1.000 P0DSM6 →
P04692 1.000 P04692 →
P84335 1.000 P84335 →
Q5KR48 1.000 Q5KR48 →
P09493 1.000 P09493 →
Q01173 1.000 Q01173 →
Q5KR47 1.000 Q5KR47 →
P42639 1.000 P42639 →
P58775 1.000 P58775 →
P19352 1.000 P19352 →
P58776 1.000 P58776 →
P58774 1.000 P58774 →
P58772 1.000 P58772 →
Q5KR49 1.000 Q5KR49 →
Q23758 1.000 Q23758 →
P06754 1.000 P06754 →
O97162 1.000 O97162 →
P13105 1.000 P13105 →
P58773 1.000 P58773 →
Q63610 1.000 Q63610 →
P04268 1.000 P04268 →
P15846 1.000 P15846 →