TPR

Nucleoprotein TPR · P12270 · TPR on Sugi Atlas →

0 patent compounds predicted against TPR, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TPR by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Low-Dose Danazol for the Treatment of Telomere Related Diseases PHASE2COMPLETED
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
SCARFREE-001: Verteporfin for Scar Prevention PHASE2NOT_YET_RECRUITING
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors PHASE1COMPLETED
Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma PHASE1WITHDRAWN
Role of the Nuclear Pore Component RANBP2 in Inflammatory Responses to Viral Infections nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells. nanUNKNOWN
Study of the Effect of Innate on the Inflammatory Response to Endotoxin nanRECRUITING
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction nanCOMPLETED
Epidemiology of Atherosclerosis nanCOMPLETED
Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis nanCOMPLETED
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease nanUNKNOWN
Mitochondrial DNA Copy Number and Leukocyte Telomere Length as Biomarkers in Type 2 Diabetic Patients nanUNKNOWN
Steroid Treatment of Idiopathic Nephrotic Syndrome nanCOMPLETED
Idiopathic Dilated Cardiomyopathy nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Genetic Polymorphism of the Androgen Receptor-Gene and Sexual Function in Middle Aged Women nanCOMPLETED
Modulatory Effect of Prodigiosin or Pioglitazone on TIME and the Crosstalk to Immune-Checkpoint Protein(s) nanNOT_YET_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis nanNOT_YET_RECRUITING
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a TPR binder may also engage these)

ProteinNameSimilarity
F6ZDS4 0.998 F6ZDS4 →
F1MA98 0.997 F1MA98 →
Q5ZKK5 0.997 Q5ZKK5 →
Q5EE04 0.994 Q5EE04 →
A1Z8P9 0.994 A1Z8P9 →
O15078 0.994 O15078 →
Q6P5D4 0.993 Q6P5D4 →
Q6A078 0.993 Q6A078 →
P85001 0.992 P85001 →
A7MD70 0.992 A7MD70 →
Q5BJF6 0.991 Q5BJF6 →
V6CJ04 0.991 V6CJ04 →
Q6AYX5 0.990 Q6AYX5 →
Q66GS9 0.990 Q66GS9 →
P16568 0.990 P16568 →
Q9UJC3 0.989 Q9UJC3 →
Q08DR9 0.989 Q08DR9 →
Q8MIT6 0.989 Q8MIT6 →
Q08C53 0.989 Q08C53 →
P85120 0.989 P85120 →
Q8NCX0 0.988 Q8NCX0 →
Q93635 0.988 Q93635 →
P34562 0.988 P34562 →
Q62868 0.988 Q62868 →
Q7PWT9 0.988 Q7PWT9 →
Q5ZMC9 0.988 Q5ZMC9 →
P97779 0.988 P97779 →
Q7YS99 0.988 Q7YS99 →
Q0WVL7 0.988 Q0WVL7 →
Q28021 0.988 Q28021 →