TTC14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TTC14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety	PHASE2	COMPLETED
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
PCD New Gene Discovery	nan	COMPLETED
Biomarker Research in Inherited Movement Disorders	nan	RECRUITING
Study of the Genetic Factors Involved in Autism and Related Disorders	nan	RECRUITING
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
A Family Study of Copy Number Variations in Patients With Autism Spectrum Disorder	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Study of a Candidate Gene Involved in Goldenhar Syndrome.	nan	COMPLETED
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
Ataxia GAA-FGF14 - Descriptive Genetic and Clinical Study	nan	ACTIVE_NOT_RECRUITING
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome	nan	ACTIVE_NOT_RECRUITING
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome	nan	UNKNOWN
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration	nan	UNKNOWN
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature Patients	nan	RECRUITING
Advancing Neurogenetic Diagnoses Through Long-Read Sequencing	nan	NOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Phenotypic and Genotypic Characterization of Subjects With Syndromic Obesity: Identifying New Candidate Genes by Exome Sequencing (OBEXOME)	nan	COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a TTC14 binder may also engage these)

Protein	Name	Similarity
Q9CSP9	—	1.000	Q9CSP9 →
P97868	—	0.995	P97868 →
P38806	—	0.993	P38806 →
Q9VGU5	—	0.992	Q9VGU5 →
Q6H7U2	—	0.992	Q6H7U2 →
Q8WML3	—	0.991	Q8WML3 →
Q7YZA2	—	0.991	Q7YZA2 →
A6QP06	—	0.991	A6QP06 →
Q3MJK5	—	0.991	Q3MJK5 →
Q76FK4	—	0.991	Q76FK4 →
Q9NRR4	—	0.991	Q9NRR4 →
Q14AX6	—	0.991	Q14AX6 →
Q5TKR9	—	0.991	Q5TKR9 →
Q8N3Z6	—	0.990	Q8N3Z6 →
Q8BMD7	—	0.990	Q8BMD7 →
Q92539	—	0.990	Q92539 →
BPTF	Nucleosome-remodeling factor subunit BPTF	0.990	landscape →
P61406	—	0.990	P61406 →
Q5HZJ0	—	0.990	Q5HZJ0 →
O23273	—	0.990	O23273 →
Q6E3D4	—	0.990	Q6E3D4 →
B5E0H4	—	0.990	B5E0H4 →
Q8RWK8	—	0.990	Q8RWK8 →
F4K4J0	—	0.990	F4K4J0 →
O14161	—	0.989	O14161 →
A7YDW0	—	0.989	A7YDW0 →
Q99PI5	—	0.989	Q99PI5 →
Q5SVQ0	—	0.989	Q5SVQ0 →
A7TQN2	—	0.989	A7TQN2 →
Q922M5	—	0.989	Q922M5 →