TTLL12 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TTLL12 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)	PHASE2/PHASE3	ACTIVE_NOT_RECRUITING
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer	PHASE1	UNKNOWN
Multiple-Vaccine Therapy in Treating Patients With Non-small Cell Lung Cancer	PHASE1	COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer	PHASE1	COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer	PHASE1	COMPLETED
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling	nan	ACTIVE_NOT_RECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Myotubular Myopathy Genetic Testing Study	nan	COMPLETED
PCM1-JAK2 in Therapy Related Neoplasms	nan	UNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods	nan	UNKNOWN
Genomic Study of Congenital Malformation	nan	UNKNOWN
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients	nan	UNKNOWN
Molecular Biology of Polycythemia and Thrombocytosis	nan	RECRUITING
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia	nan	COMPLETED
TL1A Expression in Psoriatic Skin	nan	UNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Imaging Genetics of Laryngeal Dystonia	nan	RECRUITING
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome	nan	RECRUITING
Importance of the Microtubule Cytoskeleton in Oocyte Competence	nan	COMPLETED
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism	nan	COMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Diagnosis of Primary Ciliary Dyskinesia	nan	COMPLETED
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TTLL12 binder may also engage these)

Protein	Name	Similarity
Q3UDE2	—	1.000	Q3UDE2 →
A7Z050	—	0.982	A7Z050 →
P17105	—	0.980	P17105 →
A8XXC0	—	0.979	A8XXC0 →
Q8R4H7	—	0.979	Q8R4H7 →
A2AV36	—	0.978	A2AV36 →
P10937	—	0.978	P10937 →
Q08DJ7	—	0.978	Q08DJ7 →
Q9W1V1	—	0.977	Q9W1V1 →
Q09512	—	0.977	Q09512 →
Q5RDF1	—	0.977	Q5RDF1 →
Q7QIL2	—	0.977	Q7QIL2 →
Q08DK0	—	0.977	Q08DK0 →
P0C644	—	0.977	P0C644 →
A2ARP1	—	0.977	A2ARP1 →
Q3TYX3	—	0.977	Q3TYX3 →
Q5R5N9	—	0.977	Q5R5N9 →
Q84WW3	—	0.977	Q84WW3 →
Q5XHF8	—	0.977	Q5XHF8 →
Q9D2E2	—	0.977	Q9D2E2 →
Q9QX60	—	0.977	Q9QX60 →
A0AVI4	—	0.976	A0AVI4 →
Q14AI0	—	0.976	Q14AI0 →
B4QI55	—	0.976	B4QI55 →
B3DLB3	—	0.976	B3DLB3 →
Q4KLP0	—	0.976	Q4KLP0 →
PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0.976	landscape →
Q9GL72	—	0.976	Q9GL72 →
Q3U0K8	—	0.976	Q3U0K8 →
Q8K304	—	0.976	Q8K304 →