TTN

Titin · Q8WZ42 · TTN on Sugi Atlas →

0 patent compounds predicted against TTN, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TTN by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy PHASE2/PHASE3RECRUITING
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy PHASE2/PHASE3RECRUITING
Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem PHASE2/PHASE3COMPLETED
Lifestyle and Pharmacological Interventions in Hypertrophic Cardiomyopathy PHASE2/PHASE3COMPLETED
Sacubitril/Valsartan vs Lifestyle in Hypertrophic Cardiomyopathy PHASE2COMPLETED
Trimetazidine Therapy in Hypertrophic Cardiomyopathy PHASE2UNKNOWN
Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania PHASE2COMPLETED
Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy nanUNKNOWN
Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN. nanCOMPLETED
Defining the Risk of Ventricular Tachycardia in Genetic Cardiomyopathies nanRECRUITING
Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings nanUNKNOWN
Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease nanACTIVE_NOT_RECRUITING
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level nanENROLLING_BY_INVITATION
Rheumatoid Arthritis Disease Activity and Sub Clinical Atherosclerosis nanCOMPLETED
Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women nanACTIVE_NOT_RECRUITING
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation nanRECRUITING
Dilated Cardiomyopathy-Cardiac Magnetic Resonance (DCM-CMR) Ancillary Study nanACTIVE_NOT_RECRUITING
COronary Microcirculation and Troponin Elevation in Septic Shock nanCOMPLETED
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
Molecular Analysis of Patients With Neuromuscular Disease nanRECRUITING
Urinary Titin Biomarker in DMD nanRECRUITING
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
Pediatric Cardiomyopathy Mutation Analysis nanRECRUITING
Effect of Diaphragm Stimulation During Surgery nanCOMPLETED
DMD Gene Variants and Cardiac Dysfunction in Young Males With Dystrophinopathies nanRECRUITING
Nemaline Myopathy Clinical Research Network (NM-CTRN) nanNOT_YET_RECRUITING
Characteristics of Nondystrophic Myotonias nanCOMPLETED
Predictive Factors and Consequences of Myocardial Fibrosis in Hypertrophic Cardiomyopathy nanUNKNOWN
Heart and Skeletal Muscle Problems in Neuroacanthocytosis nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a TTN binder may also engage these)

ProteinNameSimilarity
A2ASS6 0.999 A2ASS6 →
P16053 0.974 P16053 →
A8DYP0 0.972 A8DYP0 →
Q696W0 0.972 Q696W0 →
Q70IV5 0.972 Q70IV5 →
EPB41L2 Band 4.1-like protein 2 0.971 landscape →
P48193 0.971 P48193 →
Q9WV92 0.970 Q9WV92 →
Q9Y2J2 0.970 Q9Y2J2 →
O77788 0.970 O77788 →
Q28820 0.970 Q28820 →
Q86TC9 0.970 Q86TC9 →
Q8TC56 0.969 Q8TC56 →
P54938 0.969 P54938 →
Q9JIH7 0.968 Q9JIH7 →
E9QMW4 0.968 E9QMW4 →
P20810 0.968 P20810 →
O15061 0.968 O15061 →
Q06637 0.968 Q06637 →
EPB41 Protein 4.1 0.968 landscape →
J7M799 0.968 J7M799 →
Q95208 0.968 Q95208 →
Q13061 0.968 Q13061 →
NEFM Neurofilament medium polypeptide 0.967 landscape →
P11799 0.967 P11799 →
F1QIC4 0.967 F1QIC4 →
O75952 0.967 O75952 →
Q5STT6 0.967 Q5STT6 →
P16884 0.967 P16884 →
P12675 0.967 P12675 →