TXNDC17 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TXNDC17 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer	PHASE1	COMPLETED
Tolerability of Enteral NAC in Infants	PHASE1	NOT_YET_RECRUITING
S9304A Study of Protein Expression in Tumor Tissue Samples From Patients With Stage II or Stage III Rectal Cancer Enrolled in Clinical Trial SWOG-9304	nan	COMPLETED
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism	nan	UNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Autophagy Bladder Cancer	nan	UNKNOWN
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Cause of Familial Testicular Cancer	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Molecular & Clinical Evaluation of Low HDL Syndromes	nan	COMPLETED
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy	nan	COMPLETED
Telomere Disclosure and Impact on Psychological Distress and Health Behaviors	nan	COMPLETED
NCF Gene & TNFSF4 in SLE Patients	nan	UNKNOWN
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan	nan	ENROLLING_BY_INVITATION
Genetics of Familial Testicular Cancer	nan	COMPLETED
Pathogenetic Basis of Aortopathy and Aortic Valve Disease	nan	ACTIVE_NOT_RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Identification of Diabetic Nephropathy Biomarkers Through Transcriptomics	nan	COMPLETED
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a TXNDC17 binder may also engage these)

Protein	Name	Similarity
Q5REA8	—	1.000	Q5REA8 →
Q5NVN7	—	0.935	Q5NVN7 →
SAE1	SUMO-activating enzyme subunit 1	0.932	landscape →
A2VE14	—	0.929	A2VE14 →
Q6AXQ0	—	0.927	Q6AXQ0 →
P51583	—	0.926	P51583 →
Q9DCL9	—	0.925	Q9DCL9 →
PAICS	Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase	0.924	landscape →
Q5RB59	—	0.923	Q5RB59 →
Q8BGB7	—	0.921	Q8BGB7 →
Q9R1T2	—	0.919	Q9R1T2 →
Q9JIB4	—	0.918	Q9JIB4 →
HDAC8	Histone deacetylase 8	0.918	landscape →
P38024	—	0.918	P38024 →
B1WC68	—	0.916	B1WC68 →
Q0VCB2	—	0.915	Q0VCB2 →
Q9UHY7	—	0.915	Q9UHY7 →
A0JN27	—	0.915	A0JN27 →
O89050	—	0.914	O89050 →
Q6NRQ7	—	0.914	Q6NRQ7 →
Q58CY6	—	0.914	Q58CY6 →
Q5JPE7	—	0.914	Q5JPE7 →
Q67FW5	—	0.914	Q67FW5 →
Q5RB35	—	0.914	Q5RB35 →
Q9UL63	—	0.913	Q9UL63 →
Q0VD27	—	0.913	Q0VD27 →
D3ZVR7	—	0.913	D3ZVR7 →
Q86XW9	—	0.912	Q86XW9 →
P20595	—	0.912	P20595 →
Q8BUH1	—	0.912	Q8BUH1 →