U2AF1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to U2AF1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy	PHASE3	UNKNOWN
Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)	PHASE1/PHASE2	SUSPENDED
Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer	PHASE2	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Prognostic Molecular Markers in Patients With Myelodysplastic Syndrome	nan	COMPLETED
Molecular Disease Profile of Hematological Malignancies	nan	UNKNOWN
SRSF2 Gene Mutation in Patients With t-MDS/AML	nan	COMPLETED
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs	nan	UNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Biocollection in MyeloDysplastic Syndrome (P-MDS)	nan	RECRUITING
Mechanisms of Cell Death in Spinal Muscular Atrophy	nan	COMPLETED
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF)	nan	COMPLETED
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia	nan	NOT_YET_RECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED
Prospective Study of Molecular Predictors of Survival in Myelodysplastic Syndromes	nan	COMPLETED
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping	nan	UNKNOWN
NFC Changes in SLE Patients and Its Correlation With Anti-U1RNPAntibodies and Disease Activity	nan	UNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes	nan	RECRUITING
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients	nan	UNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
Patient's Derived Organoids for Drug Screening in Glioblastoma	nan	NOT_YET_RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Structural Chromosome Rearrangements and Brain Disorders	nan	ENROLLING_BY_INVITATION
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care	nan	COMPLETED
Research for Individualized Therapeutics in Rare Genetic Disease	nan	ENROLLING_BY_INVITATION
B3 for NMD: Bench to Bedside and Back	nan	ENROLLING_BY_INVITATION
Clinical Study of Spinal Muscular Atrophy	nan	COMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a U2AF1 binder may also engage these)

Protein	Name	Similarity
Q9D883	—	1.000	Q9D883 →
A1A4K8	—	1.000	A1A4K8 →
Q3T127	—	0.992	Q3T127 →
Q7TP17	—	0.991	Q7TP17 →
Q8BGJ9	—	0.989	Q8BGJ9 →
Q9S709	—	0.989	Q9S709 →
Q9FMY5	—	0.988	Q9FMY5 →
Q6AUG0	—	0.988	Q6AUG0 →
Q94535	—	0.987	Q94535 →
Q9ZQW8	—	0.985	Q9ZQW8 →
Q8WU68	—	0.984	Q8WU68 →
Q09176	—	0.982	Q09176 →
P90727	—	0.968	P90727 →
P90978	—	0.967	P90978 →
Q8VH51	—	0.966	Q8VH51 →
P17133	—	0.965	P17133 →
Q2QKB4	—	0.962	Q2QKB4 →
O23212	—	0.962	O23212 →
O01159	—	0.962	O01159 →
Q9Y5S9	—	0.962	Q9Y5S9 →
Q9DF42	—	0.962	Q9DF42 →
Q3ZCE8	—	0.962	Q3ZCE8 →
P25555	—	0.961	P25555 →
Q9ZR40	—	0.961	Q9ZR40 →
Q28BZ1	—	0.961	Q28BZ1 →
Q5RC80	—	0.960	Q5RC80 →
RBM39	RNA-binding protein 39	0.960	landscape →
Q5XI81	—	0.960	Q5XI81 →
Q21832	—	0.960	Q21832 →
Q8L716	—	0.960	Q8L716 →