UACA

Uveal autoantigen with coiled-coil domains and ankyrin repeats · Q9BZF9 · UACA on Sugi Atlas →

0 patent compounds predicted against UACA, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to UACA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis PHASE3COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma PHASE2UNKNOWN
A Phase I Study to Evaluate the Safety and Immunogenicity of PnuBioVax PHASE1COMPLETED
MSUS Versus Serum Survivin and Lubricin Levels in Evaluation of Disease Activity in JIA nanUNKNOWN
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 nanRECRUITING
Autoimmune Dysregulation in Pigmentary Glaucoma nanCOMPLETED
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome nanACTIVE_NOT_RECRUITING
Clinical and Histopathologic Characteristics of BAP1 Mutations nanCOMPLETED
The Role of Genetic Mutations and of Circulating mRNAs in Uveal Melanoma nanUNKNOWN
Natural History and Development of Spondyloarthritis nanRECRUITING
New Biopsy Technique for Uveal Melanoma nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Retrospective Comparison of the Efficacy of Methotrexate and Azathioprine as Background Treatment for Uveitis of Undetermined Origin: Single-centre Retrospective Study From 2005 to 2020 nanUNKNOWN
Genetic Analysis of Immune Disorders nanRECRUITING
Genetics and Markers of Degenerative and Inflammatory Eye Diseases nanCOMPLETED
Natural History of Photoreceptor Degeneration in USH1B: Clinical Parameters and Validation of Functional Vision Tests in MYO7A nanRECRUITING
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions nanRECRUITING
Ocular Manifestations of Granulomatosis With Polyangiitis. nanRECRUITING
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Soluble CD95 Ligand Role in the Pathophysiology of Non-infectious Active Uveitis nanCOMPLETED
Comparing Phaco/IOL Versus Phaco/IOL + Goniosynechialysis in Subjects With PACG nanCOMPLETED
Advanced OCT and Adaptive Optics Imaging in Retinal Disease (The ACAD Study) nanCOMPLETED
Rate of Progression in USH2A-related Retinal Degeneration nanACTIVE_NOT_RECRUITING
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM) nanCOMPLETED
Validation of a Molecular Prognostic Test for Eye Melanoma nanWITHDRAWN
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples nanCOMPLETED
Evaluation and Treatment of Patients With Inflammatory Eye Diseases nanCOMPLETED
iSITE: Investigation of Somatic Alterations in Tumours of the Eye nanCOMPLETED
Validation of Mesopic and Photopic Contrast Vision Tests With Respect to Nighttime Driving Ability nanCOMPLETED
Gyrate Atrophy of the Choroid and Retina nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a UACA binder may also engage these)

ProteinNameSimilarity
Q8HYY4 1.000 Q8HYY4 →
Q9GL21 1.000 Q9GL21 →
Q7YS99 0.999 Q7YS99 →
Q9P0K7 0.998 Q9P0K7 →
Q8CGB3 0.998 Q8CGB3 →
Q8NCX0 0.998 Q8NCX0 →
Q5U312 0.998 Q5U312 →
Q8CDI7 0.997 Q8CDI7 →
Q61595 0.997 Q61595 →
Q9EP71 0.997 Q9EP71 →
Q6ZU80 0.997 Q6ZU80 →
Q8WXW3 0.995 Q8WXW3 →
Q5ZKK5 0.995 Q5ZKK5 →
Q99MI1 0.995 Q99MI1 →
Q13439 0.995 Q13439 →
O15083 0.995 O15083 →
A0A8M9PQ61 0.994 A0A8M9PQ61 →
Q7Z7B0 0.994 Q7Z7B0 →
A6QR54 0.994 A6QR54 →
A7MD70 0.993 A7MD70 →
Q861Q8 0.993 Q861Q8 →
Q66H89 0.993 Q66H89 →
F4K1B4 0.993 F4K1B4 →
O55156 0.993 O55156 →
Q91785 0.993 Q91785 →
O42184 0.993 O42184 →
P97779 0.993 P97779 →
Q811U3 0.993 Q811U3 →
Q96CV9 0.993 Q96CV9 →
Q15643 0.993 Q15643 →