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Sugi Predict / Targets / UBA6

UBA6

Ubiquitin-like modifier-activating enzyme 6 · A0AVT1 · UBA6 on Sugi Atlas →

1,586 patent compounds predicted against UBA6, 1,163 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL193374 SCHEMBL193374 0.56 6/20
SCHEMBL5469557 SCHEMBL5469557 0.56 6/20
SCHEMBL10004922 SCHEMBL10004922 0.53 5/20
SCHEMBL191801 SCHEMBL191801 0.52 5/20
SCHEMBL5456247 SCHEMBL5456247 0.52 5/20
SCHEMBL10004923 SCHEMBL10004923 0.51 5/20
SCHEMBL192144 SCHEMBL192144 0.81 4/20
SCHEMBL192294 SCHEMBL192294 0.81 4/20
SCHEMBL192424 SCHEMBL192424 0.81 4/20
SCHEMBL191855 SCHEMBL191855 0.79 4/20
SCHEMBL191694 SCHEMBL191694 0.78 4/20
SCHEMBL191799 SCHEMBL191799 0.78 4/20
SCHEMBL191949 SCHEMBL191949 0.78 4/20
SCHEMBL192146 SCHEMBL192146 0.78 4/20
SCHEMBL192709 SCHEMBL192709 0.78 4/20
SCHEMBL192946 SCHEMBL192946 0.78 4/20
SCHEMBL193990 SCHEMBL193990 0.78 4/20
SCHEMBL192900 SCHEMBL192900 0.78 4/20
SCHEMBL5461275 SCHEMBL5461275 0.76 4/20
SCHEMBL5461279 SCHEMBL5461279 0.76 4/20

Clinical trials — most relevant to UBA6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Trial of Levodopa in Angelman Syndrome PHASE2/PHASE3COMPLETED
A Study to Evaluate Drug-drug Interactions and Safety Between BR3006-1, BR3006-2, and BR3006-3 in Healthy Volunteers PHASE1COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy nanCOMPLETED
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit nanCOMPLETED
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
A Natural History Study of Angelman Syndrome nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS) nanUNKNOWN
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Identification of New FTLD Genes nanUNKNOWN
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism nanCOMPLETED
Establishment of a Prospective Clinical-biological Database nanRECRUITING
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Prospective Cohort Study of Germline Variant Carriers With BRCA1 or BRCA2 nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a UBA6 binder may also engage these)

ProteinNameSimilarity
Q8C7R4 — 1.000 Q8C7R4 →
P93028 — 0.996 P93028 →
O94609 — 0.995 O94609 →
P31252 — 0.995 P31252 →
Q55C16 — 0.994 Q55C16 →
P20973 — 0.994 P20973 →
Q9Z1A5 — 0.994 Q9Z1A5 →
P31251 — 0.994 P31251 →
P92974 — 0.992 P92974 →
Q8VBW6 — 0.992 Q8VBW6 →
Q4R3L6 — 0.992 Q4R3L6 →
Q6NTW6 — 0.991 Q6NTW6 →
Q5ZIE6 — 0.990 Q5ZIE6 →
P42744 — 0.989 P42744 →
NAE1 NEDD8-activating enzyme E1 regulatory subunit 0.989 landscape →
Q7SXP2 — 0.988 Q7SXP2 →
Q9NAN1 — 0.988 Q9NAN1 →
Q8VY78 — 0.988 Q8VY78 →
Q09765 — 0.988 Q09765 →
Q9VTE9 — 0.988 Q9VTE9 →
Q9M2Q4 — 0.987 Q9M2Q4 →
A7KAL8 — 0.987 A7KAL8 →
Q58EM4 — 0.986 Q58EM4 →
Q9W3C1 — 0.986 Q9W3C1 →
O42939 — 0.986 O42939 →
Q9UT93 — 0.986 Q9UT93 →
P0DI12 — 0.985 P0DI12 →
A6ZT79 — 0.985 A6ZT79 →
Q9ZV69 — 0.985 Q9ZV69 →
W0TA05 — 0.985 W0TA05 →