Sugi Predict
/ Targets
/ UBE2V1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to UBE2V1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
| Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma |
PHASE2 | WITHDRAWN |
| Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma |
PHASE2 | SUSPENDED |
| A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome |
PHASE2 | RECRUITING |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS) |
PHASE1 | COMPLETED |
| Prospective Cohort Study of Germline Variant Carriers With BRCA1 or BRCA2 |
nan | RECRUITING |
| Endocrine Disruptors and Life STILe in Breast Cancer Development |
nan | UNKNOWN |
| Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome |
nan | RECRUITING |
| Genetics of Prostate Cancer in Young Patients |
nan | COMPLETED |
| A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS |
nan | RECRUITING |
| Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 |
nan | RECRUITING |
| HRQoL and Financial Toxicity in Patients With VEXAS Syndrome |
nan | RECRUITING |
| Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2 |
nan | UNKNOWN |
| Phenotypic and Genotypic Characterization of Subjects With Syndromic Obesity: Identifying New Candidate Genes by Exome Sequencing (OBEXOME) |
nan | COMPLETED |
| Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome |
nan | RECRUITING |
| COsegregation of VARiants in Panel of Genes |
nan | RECRUITING |
| Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management |
nan | COMPLETED |
| Impact of Different BRCA1/2 Gene Variants on Response to Therapy and Prognosis of Ovarian Cancer |
nan | RECRUITING |
| Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC) |
nan | UNKNOWN |
| Delineation of Novel Monogenic Disorders in the United Arab Emirates Population |
nan | UNKNOWN |
| A Multicenter Pharmacoepidemiological Cohort on Real Life Use of Semaglutide in Adolescents or Adults With Monogenic Obesity |
nan | RECRUITING |
| Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia |
nan | RECRUITING |
| Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants |
nan | RECRUITING |
| Clinical Utility of Pediatric Whole Exome Sequencing |
nan | COMPLETED |
| Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk |
nan | NOT_YET_RECRUITING |
| Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts |
nan | COMPLETED |
| Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. |
nan | UNKNOWN |
| Uncertain Genetic Test Results for Lynch Syndrome |
nan | COMPLETED |
| ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study |
nan | ACTIVE_NOT_RECRUITING |
| Genomic Predictors of Recurrent Pregnancy Loss |
nan | RECRUITING |
| Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a UBE2V1 binder may also engage these)