UGGT1

UDP-glucose:glycoprotein glucosyltransferase 1 · Q9NYU2 · UGGT1 on Sugi Atlas →

0 patent compounds predicted against UGGT1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to UGGT1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity PHASE4COMPLETED
SGLT2 Inhibition: Uric Acid Excretion Study PHASE4COMPLETED
Acute Effects of an Oral Fat Load on Skeletal Muscle and Hepatic Insulin Sensitivity PHASE4COMPLETED
Effect of Genetic Polymorphisms of UGT on the PKs of Indapamide in Egyptians PHASE4UNKNOWN
Effect of Glucuronosyltransferase (UGT) Genetic Variation on Pharmacokinetics of Empagliflozin PHASE3COMPLETED
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher Disease PHASE2COMPLETED
Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients PHASE2ENROLLING_BY_INVITATION
24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Participants With PMM2-CDG PHASE2COMPLETED
Safety, Efficacy Evaluation of Empagliflozin Administration for Neutropenia in Glycogenosis Type 1b and G6PC3 Deficiency PHASE2UNKNOWN
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
Pharmacokinetic Interaction Study of Efavirenz and American Ginseng in Healthy Volunteers PHASE1COMPLETED
PK and PD of YG1699 in CKD Patients With Diabetes PHASE1NOT_YET_RECRUITING
Glycosylation in Patients With Galactosaemia nanCOMPLETED
Intervention and Outcomes in Duarte Galactosemia nanCOMPLETED
Pharmacogenetic Study in Patients Received Iron Chelating Agent nanCOMPLETED
Role of Metabolic Enzymes in Non-Melanoma Skin Cancer nanCOMPLETED
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation nanCOMPLETED
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
Effect of an Polyphenolic Beverage in Healthy Volunteers nanACTIVE_NOT_RECRUITING
Cross-Sectional and Longitudinal Studies of Pre-Diabetes in the Pima Indians nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
Evaluation of Blood Protein O-GlcNAcylation Levels in Children nanRECRUITING
Identification and Characterization of Monogenic Diabetes nanCOMPLETED
Evaluation of Blood and Cardiac Protein O-GlcNAcylation Levels in Cardiac Surgery in Children nanRECRUITING
Role of the Liver in Glucose Homeostasis Using Metabolic Imaging nanCOMPLETED
EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND) nanRECRUITING
Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance nanCOMPLETED
1,5-AG as a Marker of Postprandial Hyperglycemia and Glucose Variability in Well-controlled Type 2 Diabetes Mellitus nanCOMPLETED
Hepatic Substrate Flux Rates in Type 2 Diabetes nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a UGGT1 binder may also engage these)

ProteinNameSimilarity
Q9JLA3 1.000 Q9JLA3 →
Q6P5E4 1.000 Q6P5E4 →
Q9NYU1 0.998 Q9NYU1 →
Q0WL80 0.997 Q0WL80 →
Q09332 0.992 Q09332 →
Q8W4J3 0.987 Q8W4J3 →
A0A8M1N5Y4 0.984 A0A8M1N5Y4 →
Q86S40 0.983 Q86S40 →
Q80TN4 0.983 Q80TN4 →
Q9WTZ2 0.983 Q9WTZ2 →
Q5ZKZ4 0.983 Q5ZKZ4 →
Q6AXS4 0.983 Q6AXS4 →
Q9Y2G8 0.983 Q9Y2G8 →
Q8WUM0 0.982 Q8WUM0 →
Q9STV0 0.982 Q9STV0 →
Q765A7 0.982 Q765A7 →
Q9FYH7 0.982 Q9FYH7 →
O64758 0.982 O64758 →
Q66J01 0.982 Q66J01 →
Q66GQ3 0.982 Q66GQ3 →
Q2KHZ2 0.981 Q2KHZ2 →
P81134 0.981 P81134 →
Q6NUA7 0.981 Q6NUA7 →
Q3UUQ7 0.981 Q3UUQ7 →
G5ED46 0.981 G5ED46 →
Q9LW26 0.980 Q9LW26 →
Q60432 0.980 Q60432 →
Q9Z2A8 0.980 Q9Z2A8 →
Q9WTZ3 0.980 Q9WTZ3 →
A1XD95 0.980 A1XD95 →