Sugi Predict

Sugi Predict / Targets / UPF1

UPF1

Regulator of nonsense transcripts 1 · Q92900 · UPF1 on Sugi Atlas →

0 patent compounds predicted against UPF1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to UPF1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Developing a Pipeline to Employ RNA-Seq as a Complementary Diagnostic Tool in Rare Diseases nanRECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
SRSF2 Gene Mutation in Patients With t-MDS/AML nanCOMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Correction of Nonsense Mutations in Cystic Fibrosis nanRECRUITING
Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia nanNOT_YET_RECRUITING
Research for Individualized Therapeutics in Rare Genetic Disease nanENROLLING_BY_INVITATION
Genetic Factors Affecting the Severity of Beta Thalassemia nanCOMPLETED
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing nanRECRUITING
EKLF Gene Expression in β-thalassemia nanNOT_YET_RECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Transcriptomic Analysis of Fibroblasts and Blood in Patients With Rare Diseases nanRECRUITING
Peri-implantitis and MMP-8 nanCOMPLETED
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants nanRECRUITING
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia nanRECRUITING
RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2 nanCOMPLETED
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Molecular Testing of Cancer by Integrated Genomic, Transcriptomic, and Proteomic Analysis nanUNKNOWN
Precision Diagnosis and Therapy for Rare Diseases by Interpreting Non-coding Genomes nanRECRUITING
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders nanCOMPLETED
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Cutaneous Mastocytosis in Children: Analysis of Somatic and Germline Mutations nanCOMPLETED
Uncovering the Etiologies of Non-immune Hydrops Fetalis nanENROLLING_BY_INVITATION
Method of Genetic Analysis in Genodermatoses nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a UPF1 binder may also engage these)

ProteinNameSimilarity
Q9FJR0 — 1.000 Q9FJR0 →
Q9EPU0 — 1.000 Q9EPU0 →
O76512 — 0.997 O76512 →
F1RCY6 — 0.996 F1RCY6 →
Q9HEH1 — 0.996 Q9HEH1 →
Q98TR3 — 0.996 Q98TR3 →
Q9VYS3 — 0.994 Q9VYS3 →
Q09820 — 0.991 Q09820 →
Q7ZU90 — 0.991 Q7ZU90 →
F4IF36 — 0.991 F4IF36 →
P30771 — 0.989 P30771 →
Q91ZW3 — 0.988 Q91ZW3 →
Q12756 — 0.988 Q12756 →
P25799 — 0.988 P25799 →
A4RKC3 — 0.987 A4RKC3 →
Q4WVE3 — 0.987 Q4WVE3 →
Q5A1M3 — 0.987 Q5A1M3 →
B4LX81 — 0.987 B4LX81 →
A6H8I2 — 0.987 A6H8I2 →
Q60575 — 0.987 Q60575 →
Q7QCW2 — 0.987 Q7QCW2 →
SMARCA5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 0.987 landscape →
O18017 — 0.987 O18017 →
Q95LP3 — 0.986 Q95LP3 →
Q9AWM8 — 0.986 Q9AWM8 →
O45380 — 0.986 O45380 →
P38144 — 0.986 P38144 →
Q05AS3 — 0.986 Q05AS3 →
P38935 — 0.986 P38935 →
O74842 — 0.986 O74842 →