VDAC2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Erastin (SCHEMBL4457820)	1.00	1/20
Erastin (SCHEMBL22213543)	1.00	1/20
Erastin (SCHEMBL29370998)	1.00	1/20
Erastin (SCHEMBL31385520)	1.00	1/20
SCHEMBL13633718	0.89	1/20
SCHEMBL1593568	0.88	1/20
SCHEMBL25793246	0.87	1/20
SCHEMBL5440840	0.85	1/20
SCHEMBL14222558	0.85	1/20
SCHEMBL4519119	0.85	1/20
SCHEMBL4463410	0.84	1/20
SCHEMBL4461445	0.83	1/20
SCHEMBL12610487	0.83	1/20
SCHEMBL4457851	0.82	1/20
SCHEMBL14010407	0.81	1/20
SCHEMBL14010414	0.81	1/20
SCHEMBL12610471	0.81	1/20
SCHEMBL18387789	0.81	1/20
SCHEMBL4459138	0.80	1/20
SCHEMBL4452788	0.79	1/20

Clinical trials — most relevant to VDAC2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Impact if Desflurane Preconditioning on the Content of the Phospho-GSK-3b in the Rat's Neurons in the Model of I/R	PHASE4	WITHDRAWN
The Effect of Pregabalin and Etoricoxib on Pain Alone Versus in Combination	PHASE4	UNKNOWN
The Re-Prosper HF Study	PHASE2/PHASE3	COMPLETED
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)	PHASE3	COMPLETED
Role of Intralipid in Management of Organophosphorus Poisoning	PHASE2/PHASE3	WITHDRAWN
Desflurane vs. Propofol for Cardiac Anesthesia	PHASE3	RECRUITING
Early Study on Tamoxifen Safety/Tolerability in Cystic Fibrosis Patients Unable to Use CFTR Modulators.	PHASE2	NOT_YET_RECRUITING
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease	PHASE2	COMPLETED
A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours	PHASE1	COMPLETED
Genetic Sources of Variability of the Adaptation of the Ventricular Repolarisation	PHASE1	COMPLETED
Genetic Determinants of Sudden Cardiac Death	nan	COMPLETED
The Energetic Origin of Neurodegeneration in MS	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
TRPM2 Gene Polymorphism, NLRP3 Inflammasome Expression in Vitiligo Patients	nan	ACTIVE_NOT_RECRUITING
Mitochondrial Assessment in Critical Ill Patients in Intensive Care	nan	NOT_YET_RECRUITING
Profiling Vulvodynia Based on Neurobiological and Behavioral Endophenotypes	nan	COMPLETED
Vacuolar ATPase and Drug Resistance of High Grade Gliomas	nan	UNKNOWN
The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain.	nan	UNKNOWN
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside	nan	UNKNOWN
Mitochondrial Dysfunction in Phelan-McDermid Syndrome	nan	COMPLETED
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)	nan	COMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
Molecular Genetic Screening and Identification of Congenital Arrhythmogenic Diseases	nan	UNKNOWN
Comparison of Two Types of Calcium (Ca²⁺) Ionophore Treatments for Oocyte Activation in Cases of Suboptimal Fertilization Potential	nan	NOT_YET_RECRUITING
Lipid Emulsion for Reversal of Spinal Anesthesia in Ambulatory Surgery	nan	RECRUITING
IVF Outcome in Polycystic Ovary Syndrome Patients	nan	UNKNOWN
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH)	nan	RECRUITING
Predicting Pancreatic Necrosis Using mitDNA	nan	UNKNOWN
Evaluation of the Effects of KCNQ1 Mutation on Insulin Tolerance and Obsessive Compulsive Features in Long QT Romano-Ward Syndrome Patients.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a VDAC2 binder may also engage these)

Protein	Name	Similarity
P68002	—	1.000	P68002 →
P68003	—	1.000	P68003 →
Q9MZ15	—	1.000	Q9MZ15 →
P81155	—	1.000	P81155 →
Q60932	—	1.000	Q60932 →
P86223	—	1.000	P86223 →
Q60930	—	1.000	Q60930 →
P82013	—	0.994	P82013 →
Q9Z2L0	—	0.992	Q9Z2L0 →
VDAC1	Non-selective voltage-gated ion channel VDAC1	0.992	landscape →
A0A6P7EFR0	—	0.989	A0A6P7EFR0 →
P81004	—	0.987	P81004 →
P45879	—	0.986	P45879 →
Q9MZ16	—	0.986	Q9MZ16 →
Q60931	—	0.985	Q60931 →
Q9TT15	—	0.984	Q9TT15 →
Q9MZ13	—	0.983	Q9MZ13 →
Q9TT13	—	0.983	Q9TT13 →
Q5R7V4	—	0.976	Q5R7V4 →
Q29380	—	0.976	Q29380 →
VDAC3	Non-selective voltage-gated ion channel VDAC3	0.975	landscape →
P42055	—	0.971	P42055 →
Q9R1Z0	—	0.969	Q9R1Z0 →
P42056	—	0.966	P42056 →
Q9SRH5	—	0.929	Q9SRH5 →
P42054	—	0.928	P42054 →
Q9CZR3	—	0.927	Q9CZR3 →
P07144	—	0.925	P07144 →
P46274	—	0.923	P46274 →
Q969M1	—	0.923	Q969M1 →