Sugi Predict

Sugi Predict / Targets / WAPL

WAPL

Wings apart-like protein homolog · Q7Z5K2 · WAPL on Sugi Atlas →

0 patent compounds predicted against WAPL, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to WAPL by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment PHASE2/PHASE3RECRUITING
Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome PHASE2UNKNOWN
Gene Therapy for Wiskott-Aldrich Syndrome PHASE1/PHASE2COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Natural History and Genetic Studies of Usher Syndrome nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Impact of Elastin Mediated Vascular Stiffness on End Organs nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing nanRECRUITING
Molecular Genetics of Retinal Degenerations nanCOMPLETED
Genetic Basis of Non Syndromic Congenital Diaphragmatic Hernia nanCOMPLETED
Congenital Aniridia Patient Questionnaire nanRECRUITING
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
Genetic Variants in Linear Localized Scleroderma nanCOMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Epidemiological and Genetic Studies of Body Mass Index nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
Chest Wall Deformities in Children - Epidemiological Data nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a WAPL binder may also engage these)

ProteinNameSimilarity
Q65Z40 — 1.000 Q65Z40 →
A6QP06 — 0.997 A6QP06 →
Q9NQW6 — 0.996 Q9NQW6 →
Q2PFD7 — 0.995 Q2PFD7 →
Q76FK4 — 0.995 Q76FK4 →
Q8WML3 — 0.994 Q8WML3 →
Q8RWK8 — 0.994 Q8RWK8 →
KMT5B Histone-lysine N-methyltransferase KMT5B 0.994 landscape →
Q92539 — 0.994 Q92539 →
Q99PI5 — 0.994 Q99PI5 →
Q9NYI0 — 0.994 Q9NYI0 →
P10244 — 0.994 P10244 →
Q811D2 — 0.994 Q811D2 →
BLM RecQ-like DNA helicase BLM 0.994 landscape →
BPTF Nucleosome-remodeling factor subunit BPTF 0.994 landscape →
Q6DFV7 — 0.994 Q6DFV7 →
A0A0R4IBK5 — 0.993 A0A0R4IBK5 →
P62292 — 0.993 P62292 →
Q6IRN6 — 0.993 Q6IRN6 →
A0JMT0 — 0.993 A0JMT0 →
Q95JJ5 — 0.993 Q95JJ5 →
Q0VF22 — 0.993 Q0VF22 →
Q6KAQ7 — 0.993 Q6KAQ7 →
Q5W0B1 — 0.993 Q5W0B1 →
P62291 — 0.993 P62291 →
Q9Z2U2 — 0.993 Q9Z2U2 →
Q5FBB7 — 0.993 Q5FBB7 →
A6H5Y1 — 0.993 A6H5Y1 →
Q5HZN1 — 0.993 Q5HZN1 →
A8KBE0 — 0.992 A8KBE0 →