ADAMTS7 — 368 ClinVar variants
All ClinVar germline ADAMTS7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 326 flagged for review →
2 Conflicting · 9 Benign · 1 Benign/Likely benign · 40 Likely benign · 316 Uncertain significance
Full ADAMTS7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 326
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 1
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
Predictors lean, ClinVar uncertain 169
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 169
- ADAMTS7 p.Ala1019Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala1049Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala1166Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala1267Ser Uncertain significance Single submitter
- ADAMTS7 p.Ala1267Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala1383Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala1405Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala1405Val Uncertain significance Single submitter
- ADAMTS7 p.Ala1431Val Uncertain significance Single submitter
- ADAMTS7 p.Ala188Ser Uncertain significance Single submitter
- ADAMTS7 p.Ala25Ser Uncertain significance Single submitter
- ADAMTS7 p.Ala28Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala423Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala424Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala636Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala641Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala771Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala980Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala984Asp Uncertain significance Single submitter
- ADAMTS7 p.Arg1029His Uncertain significance Single submitter
- ADAMTS7 p.Arg1094Gly Uncertain significance Single submitter
- ADAMTS7 p.Arg1094Pro Uncertain significance Single submitter
- ADAMTS7 p.Arg1211Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1227Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1387Gly Uncertain significance Single submitter
- ADAMTS7 p.Arg1411Thr Uncertain significance Single submitter
- ADAMTS7 p.Arg1437His Uncertain significance Single submitter
- ADAMTS7 p.Arg1493Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1499Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1638Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1666His Uncertain significance Single submitter
- ADAMTS7 p.Arg1682Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1686His Uncertain significance Single submitter
- ADAMTS7 p.Arg174Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg227Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg515Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg563Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg772Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg909His Uncertain significance Single submitter
- ADAMTS7 p.Arg938His Uncertain significance Single submitter
- ADAMTS7 p.Arg995Gln Uncertain significance Single submitter
- ADAMTS7 p.Asn1043Ser Uncertain significance Single submitter
- ADAMTS7 p.Asn1155Ser Uncertain significance Single submitter
- ADAMTS7 p.Asn94Ser Uncertain significance Single submitter
- ADAMTS7 p.Asp1220His Uncertain significance Single submitter
- ADAMTS7 p.Asp136Tyr Uncertain significance Single submitter
- ADAMTS7 p.Asp650Ala Uncertain significance Single submitter
- ADAMTS7 p.Cys1516Ser Uncertain significance Single submitter
- ADAMTS7 p.Cys1596Arg Uncertain significance Single submitter
- ADAMTS7 p.Cys942Tyr Uncertain significance Single submitter
- ADAMTS7 p.Gln1488Arg Uncertain significance Single submitter
- ADAMTS7 p.Gln1681His Uncertain significance Single submitter
- ADAMTS7 p.Gln179Arg Uncertain significance Single submitter
- ADAMTS7 p.Gln224Leu Uncertain significance Single submitter
- ADAMTS7 p.Gln564His Uncertain significance Single submitter
- ADAMTS7 p.Gln762His Uncertain significance Single submitter
- ADAMTS7 p.Gln877Arg Uncertain significance Single submitter
- ADAMTS7 p.Glu1014Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu1083Gly Uncertain significance Single submitter
- ADAMTS7 p.Glu1121Gly Uncertain significance Single submitter
- ADAMTS7 p.Glu1160Gly Uncertain significance Single submitter
- ADAMTS7 p.Glu1191Gln Uncertain significance Single submitter
- ADAMTS7 p.Glu1311Gly Uncertain significance Single submitter
- ADAMTS7 p.Glu140Gln Uncertain significance Single submitter
- ADAMTS7 p.Glu140Gly Uncertain significance Single submitter
- ADAMTS7 p.Glu1534Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu213Gly Uncertain significance Single submitter
- ADAMTS7 p.Glu256Gln Uncertain significance Single submitter
- ADAMTS7 p.Glu630Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu705Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu742Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu817Lys Uncertain significance Single submitter
- ADAMTS7 p.Gly1079Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly1079Glu Uncertain significance Single submitter
- ADAMTS7 p.Gly1090Val Uncertain significance Single submitter
- ADAMTS7 p.Gly1138Ser Uncertain significance Single submitter
- ADAMTS7 p.Gly115Ser Uncertain significance Single submitter
- ADAMTS7 p.Gly1199Ser Uncertain significance Single submitter
- ADAMTS7 p.Gly1345Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly1358Asp Uncertain significance Single submitter
- ADAMTS7 p.Gly1587Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly3Ser Uncertain significance Single submitter
- ADAMTS7 p.Gly409Glu Uncertain significance Single submitter
- ADAMTS7 p.Gly681Ser Uncertain significance Single submitter
- ADAMTS7 p.Gly702Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly716Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly838Val Uncertain significance Single submitter
- ADAMTS7 p.His1024Tyr Uncertain significance Single submitter
- ADAMTS7 p.His1025Tyr Uncertain significance Single submitter
- ADAMTS7 p.His1099Gln Uncertain significance Single submitter
- ADAMTS7 p.His1386Asp Uncertain significance Single submitter
- ADAMTS7 p.His1568Gln Uncertain significance Single submitter
- ADAMTS7 p.His334Gln Uncertain significance Single submitter
- ADAMTS7 p.His601Leu Uncertain significance Single submitter
- ADAMTS7 p.His803Tyr Uncertain significance Single submitter
- ADAMTS7 p.Ile1164Val Uncertain significance Single submitter
- ADAMTS7 p.Leu1153Trp Uncertain significance Single submitter
- ADAMTS7 p.Leu1174Pro Uncertain significance Single submitter
- ADAMTS7 p.Leu139Arg Uncertain significance Single submitter
- ADAMTS7 p.Leu247Pro Uncertain significance Single submitter
- ADAMTS7 p.Leu589Pro Uncertain significance Single submitter
- ADAMTS7 p.Leu67Val Uncertain significance Single submitter
- ADAMTS7 p.Lys571Arg Uncertain significance Single submitter
- ADAMTS7 p.Met1347Val Uncertain significance Single submitter
- ADAMTS7 p.Met610Ile Uncertain significance Single submitter
- ADAMTS7 p.Met683Thr Uncertain significance Single submitter
- ADAMTS7 p.Phe278Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1003Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro1023Arg Uncertain significance Single submitter
- ADAMTS7 p.Pro1084Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1096Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1142Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1142Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro1143Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1187Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1208Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1233Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1242Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1242Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro1296Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1312Ala Uncertain significance Single submitter
- ADAMTS7 p.Pro1312Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1365Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1407Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro1454Ala Uncertain significance Single submitter
- ADAMTS7 p.Pro172Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro189Ala Uncertain significance Single submitter
- ADAMTS7 p.Pro189Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro286Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro33Ala Uncertain significance Single submitter
- ADAMTS7 p.Pro353Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro353Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro79Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro819Leu Uncertain significance Single submitter
- ADAMTS7 p.Ser1034Leu Uncertain significance Single submitter
- ADAMTS7 p.Ser1077Tyr Uncertain significance Single submitter
- ADAMTS7 p.Ser1381Arg Uncertain significance Single submitter
- ADAMTS7 p.Ser1642Pro Uncertain significance Single submitter
- ADAMTS7 p.Ser461Leu Uncertain significance Single submitter
- ADAMTS7 p.Ser551Leu Uncertain significance Single submitter
- ADAMTS7 p.Ser6Gly Uncertain significance Single submitter
- ADAMTS7 p.Thr1040Asn Uncertain significance Single submitter
- ADAMTS7 p.Thr1107Ala Uncertain significance Single submitter
- ADAMTS7 p.Thr1189Asn Uncertain significance Single submitter
- ADAMTS7 p.Thr1214Ala Uncertain significance Single submitter
- ADAMTS7 p.Thr1286Ala Uncertain significance Single submitter
- ADAMTS7 p.Thr1314Ala Uncertain significance Single submitter
- ADAMTS7 p.Thr1561Ala Uncertain significance Single submitter
- ADAMTS7 p.Thr1599Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr1648Met Uncertain significance Single submitter
Predictors split 156
The independent predictors disagree with each other — read with care. · showing the 150 best-reviewed of 156
- ADAMTS7 p.Arg218His Likely benign Multiple submitters
- ADAMTS7 p.Thr307Met Benign Multiple submitters
- ADAMTS7 p.Ala11Glu Uncertain significance Single submitter
- ADAMTS7 p.Ala23Asp Uncertain significance Single submitter
- ADAMTS7 p.Ala609Val Uncertain significance Single submitter
- ADAMTS7 p.Ala647Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala647Val Uncertain significance Single submitter
- ADAMTS7 p.Ala682Thr Uncertain significance Single submitter
- ADAMTS7 p.Ala720Val Uncertain significance Single submitter
- ADAMTS7 p.Ala923Thr Uncertain significance Single submitter
- ADAMTS7 p.Arg1139Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg1437Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg1442Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1451Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1456Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg1461Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg1476His Uncertain significance Single submitter
- ADAMTS7 p.Arg1485Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1563Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1591Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1621Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1635His Uncertain significance Single submitter
- ADAMTS7 p.Arg1640His Uncertain significance Single submitter
- ADAMTS7 p.Arg1650Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg1650His Uncertain significance Single submitter
- ADAMTS7 p.Arg1654Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg1661His Uncertain significance Single submitter
- ADAMTS7 p.Arg1666Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg1682Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg1685Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg174Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg186Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg218Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg222Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg229Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg236Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg293Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg35His Uncertain significance Single submitter
- ADAMTS7 p.Arg40Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg430Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg433His Uncertain significance Single submitter
- ADAMTS7 p.Arg442Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg552Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg581Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg581His Uncertain significance Single submitter
- ADAMTS7 p.Arg583Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg65Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg661Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg661Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg686Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg686His Uncertain significance Single submitter
- ADAMTS7 p.Arg723His Uncertain significance Single submitter
- ADAMTS7 p.Arg726Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg740Gln Uncertain significance Single submitter
- ADAMTS7 p.Arg772His Uncertain significance Single submitter
- ADAMTS7 p.Arg866Trp Uncertain significance Single submitter
- ADAMTS7 p.Arg902Leu Uncertain significance Single submitter
- ADAMTS7 p.Arg909Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg929Gln Likely benign Single submitter
- ADAMTS7 p.Arg92Leu Uncertain significance Single submitter
- ADAMTS7 p.Arg938Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg964Cys Uncertain significance Single submitter
- ADAMTS7 p.Arg995Trp Uncertain significance Single submitter
- ADAMTS7 p.Asn519Ser Likely benign Single submitter
- ADAMTS7 p.Asn799Lys Uncertain significance Single submitter
- ADAMTS7 p.Asn98His Uncertain significance Single submitter
- ADAMTS7 p.Asp1062Asn Uncertain significance Single submitter
- ADAMTS7 p.Asp1085Tyr Uncertain significance Single submitter
- ADAMTS7 p.Asp441Glu Uncertain significance Single submitter
- ADAMTS7 p.Asp52Glu Uncertain significance Single submitter
- ADAMTS7 p.Glu1018Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu1074Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu1534Asp Uncertain significance Single submitter
- ADAMTS7 p.Glu1554Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu1626Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu535Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu638Val Uncertain significance Single submitter
- ADAMTS7 p.Glu642Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu858Lys Uncertain significance Single submitter
- ADAMTS7 p.Glu979Lys Likely benign Single submitter
- ADAMTS7 p.Glu986Lys Uncertain significance Single submitter
- ADAMTS7 p.Gly117Asp Uncertain significance Single submitter
- ADAMTS7 p.Gly1441Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly1441Asp Uncertain significance Single submitter
- ADAMTS7 p.Gly1480Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly205Arg Uncertain significance Single submitter
- ADAMTS7 p.Gly402Asp Uncertain significance Single submitter
- ADAMTS7 p.Gly402Ser Uncertain significance Single submitter
- ADAMTS7 p.Gly55Ser Uncertain significance Single submitter
- ADAMTS7 p.His1346Tyr Uncertain significance Single submitter
- ADAMTS7 p.His308Tyr Uncertain significance Single submitter
- ADAMTS7 p.His606Tyr Uncertain significance Single submitter
- ADAMTS7 p.Ile291Thr Uncertain significance Single submitter
- ADAMTS7 p.Leu1001Met Uncertain significance Single submitter
- ADAMTS7 p.Leu1125Met Likely benign Single submitter
- ADAMTS7 p.Leu19Pro Uncertain significance Single submitter
- ADAMTS7 p.Leu43Met Uncertain significance Single submitter
- ADAMTS7 p.Leu849Ser Likely benign Single submitter
- ADAMTS7 p.Lys327Asn Uncertain significance Single submitter
- ADAMTS7 p.Phe1059Leu Uncertain significance Single submitter
- ADAMTS7 p.Phe484Cys Uncertain significance Single submitter
- ADAMTS7 p.Phe748Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1096His Uncertain significance Single submitter
- ADAMTS7 p.Pro1110Arg Uncertain significance Single submitter
- ADAMTS7 p.Pro1130Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro126Leu Conflicting Single submitter
- ADAMTS7 p.Pro126Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro1312Arg Uncertain significance Single submitter
- ADAMTS7 p.Pro1318Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro1389Arg Uncertain significance Single submitter
- ADAMTS7 p.Pro1511Arg Uncertain significance Single submitter
- ADAMTS7 p.Pro1520Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1622Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro1630Arg Uncertain significance Single submitter
- ADAMTS7 p.Pro1658Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro33Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro368Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro463Leu Likely benign Single submitter
- ADAMTS7 p.Pro593Leu Uncertain significance Single submitter
- ADAMTS7 p.Pro64Ser Uncertain significance Single submitter
- ADAMTS7 p.Pro653Thr Uncertain significance Single submitter
- ADAMTS7 p.Pro782Ser Uncertain significance Single submitter
- ADAMTS7 p.Ser1131Arg Uncertain significance Single submitter
- ADAMTS7 p.Ser1140Phe Uncertain significance Single submitter
- ADAMTS7 p.Ser1244Cys Uncertain significance Single submitter
- ADAMTS7 p.Ser1375Cys Uncertain significance Single submitter
- ADAMTS7 p.Ser1375Tyr Uncertain significance Single submitter
- ADAMTS7 p.Ser605Gly Uncertain significance Single submitter
- ADAMTS7 p.Ser701Asn Uncertain significance Single submitter
- ADAMTS7 p.Thr1091Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr1186Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr1465Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr1562Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr1571Met Uncertain significance Single submitter
- ADAMTS7 p.Thr1625Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr203Ile Uncertain significance Single submitter
- ADAMTS7 p.Thr988Ile Uncertain significance Single submitter
- ADAMTS7 p.Tyr478His Uncertain significance Single submitter
- ADAMTS7 p.Tyr60Asn Uncertain significance Single submitter
- ADAMTS7 p.Tyr60Cys Uncertain significance Single submitter
- ADAMTS7 p.Val1287Ile Uncertain significance Single submitter
- ADAMTS7 p.Val1487Met Uncertain significance Single submitter
- ADAMTS7 p.Val1574Met Uncertain significance Single submitter
- ADAMTS7 p.Val1631Ile Uncertain significance Single submitter
- ADAMTS7 p.Val206Met Uncertain significance Single submitter
- ADAMTS7 p.Val255Leu Uncertain significance Single submitter
- ADAMTS7 p.Val408Ile Uncertain significance Single submitter
- ADAMTS7 p.Val408Phe Uncertain significance Single submitter
- ADAMTS7 p.Val530Met Uncertain significance Single submitter
- ADAMTS7 p.Val537Met Uncertain significance Single submitter
All ADAMTS7 variants
Conflicting classifications of pathogenicity 2
- p.Pro126Leu Single submitter ⚠
- p.Pro1389Ser Single submitter ⚠
Benign 9
- p.Pro568= Multiple submitters
- p.Thr307Met Multiple submitters ⚠
- p.Asp458Asn Single submitter
- p.Ser214Pro Single submitter
- p.Val238= Single submitter
- p.Val248= Single submitter
- c.100+3925C>T No assertion criteria Three Vessel Coronary Disease
- c.101-872A>G No assertion criteria Three Vessel Coronary Disease
- c.1322+1499C>T No assertion criteria Three Vessel Coronary Disease
Benign/Likely benign 1
- p.Cys1553= Multiple submitters
Likely benign 40
- p.Arg218His Multiple submitters ⚠
- p.Ser237= Multiple submitters
- p.Ala1258Val Single submitter
- p.Ala647= Single submitter
- p.Arg1139His Single submitter
- p.Arg1457His Single submitter
- p.Arg195Gln Single submitter
- p.Arg227= Single submitter
- p.Arg352Gln Single submitter
- p.Arg929Gln Single submitter ⚠
- p.Arg964His Single submitter
- p.Asn519Ser Single submitter ⚠
- p.Asp1053Gly Single submitter
- p.Asp862= Single submitter
- p.Glu1122= Single submitter
- p.Glu979Lys Single submitter ⚠
- p.Gly999Asp Single submitter
- p.His1024Arg Single submitter
- p.His1073= Single submitter
- p.Ile456Val Single submitter
- p.Leu1125Met Single submitter ⚠
- p.Leu1125Pro Single submitter
- p.Leu476= Single submitter
- p.Leu849Ser Single submitter ⚠
- p.Lys1219Glu Single submitter
- p.Met1303Thr Single submitter
- p.Met556Val Single submitter
- p.Met683Val Single submitter
- p.Pro1084= Single submitter
- p.Pro1096Thr Single submitter
- p.Pro1435= Single submitter
- p.Pro1505= Single submitter
- p.Pro463Leu Single submitter ⚠
- p.Ser471Gly Single submitter
- p.Thr1162Ala Single submitter
- p.Thr1571= Single submitter
- p.Thr1662Ala Single submitter
- p.Tyr1078= Single submitter
- p.Tyr770= Single submitter
- p.Val1124Ala Single submitter
Uncertain significance 316
Showing the top 300 by review status; the full set is in the sitemap.
- p.Ala1019Thr Single submitter ⚠
- p.Ala1049Thr Single submitter ⚠
- p.Ala1166Thr Single submitter ⚠
- p.Ala11Glu Single submitter ⚠
- p.Ala1267Ser Single submitter ⚠
- p.Ala1267Thr Single submitter ⚠
- p.Ala1383Thr Single submitter ⚠
- p.Ala1405Thr Single submitter ⚠
- p.Ala1405Val Single submitter ⚠
- p.Ala1431Val Single submitter ⚠
- p.Ala188Ser Single submitter ⚠
- p.Ala23Asp Single submitter ⚠
- p.Ala25Ser Single submitter ⚠
- p.Ala28Thr Single submitter ⚠
- p.Ala423Thr Single submitter ⚠
- p.Ala424Thr Single submitter ⚠
- p.Ala609Val Single submitter ⚠
- p.Ala636Thr Single submitter ⚠
- p.Ala641Thr Single submitter ⚠
- p.Ala647Thr Single submitter ⚠
- p.Ala647Val Single submitter ⚠
- p.Ala682Thr Single submitter ⚠
- p.Ala720Val Single submitter ⚠
- p.Ala771Thr Single submitter ⚠
- p.Ala923Thr Single submitter ⚠
- p.Ala980Thr Single submitter ⚠
- p.Ala984Asp Single submitter ⚠
- p.Arg1029His Single submitter ⚠
- p.Arg1094Gly Single submitter ⚠
- p.Arg1094Pro Single submitter ⚠
- p.Arg1139Cys Single submitter ⚠
- p.Arg1211Gln Single submitter ⚠
- p.Arg1227Gln Single submitter ⚠
- p.Arg1387Gly Single submitter ⚠
- p.Arg1411Thr Single submitter ⚠
- p.Arg1437Cys Single submitter ⚠
- p.Arg1437His Single submitter ⚠
- p.Arg1442Trp Single submitter ⚠
- p.Arg1451Trp Single submitter ⚠
- p.Arg1456Cys Single submitter ⚠
- p.Arg1461Gln Single submitter ⚠
- p.Arg1476His Single submitter ⚠
- p.Arg1485Trp Single submitter ⚠
- p.Arg1493Gln Single submitter ⚠
- p.Arg1499Gln Single submitter ⚠
- p.Arg1563Trp Single submitter ⚠
- p.Arg1591Trp Single submitter ⚠
- p.Arg1621Trp Single submitter ⚠
- p.Arg1635His Single submitter ⚠
- p.Arg1638Gln Single submitter ⚠
- p.Arg1640His Single submitter ⚠
- p.Arg1650Cys Single submitter ⚠
- p.Arg1650His Single submitter ⚠
- p.Arg1654Cys Single submitter ⚠
- p.Arg1661His Single submitter ⚠
- p.Arg1666Cys Single submitter ⚠
- p.Arg1666His Single submitter ⚠
- p.Arg1682Gln Single submitter ⚠
- p.Arg1682Trp Single submitter ⚠
- p.Arg1685Cys Single submitter ⚠
- p.Arg1686His Single submitter ⚠
- p.Arg174Gln Single submitter ⚠
- p.Arg174Trp Single submitter ⚠
- p.Arg186Cys Single submitter ⚠
- p.Arg218Cys Single submitter ⚠
- p.Arg222Trp Single submitter ⚠
- p.Arg227Gln Single submitter ⚠
- p.Arg229Trp Single submitter ⚠
- p.Arg236Gln Single submitter ⚠
- p.Arg293Cys Single submitter ⚠
- p.Arg35His Single submitter ⚠
- p.Arg40Trp Single submitter ⚠
- p.Arg430Cys Single submitter ⚠
- p.Arg433His Single submitter ⚠
- p.Arg442Cys Single submitter ⚠
- p.Arg515Trp Single submitter ⚠
- p.Arg552Trp Single submitter ⚠
- p.Arg563Gln Single submitter ⚠
- p.Arg581Cys Single submitter ⚠
- p.Arg581His Single submitter ⚠
- p.Arg583Cys Single submitter ⚠
- p.Arg65Cys Single submitter ⚠
- p.Arg661Gln Single submitter ⚠
- p.Arg661Trp Single submitter ⚠
- p.Arg686Cys Single submitter ⚠
- p.Arg686His Single submitter ⚠
- p.Arg723His Single submitter ⚠
- p.Arg726Cys Single submitter ⚠
- p.Arg740Gln Single submitter ⚠
- p.Arg772Cys Single submitter ⚠
- p.Arg772His Single submitter ⚠
- p.Arg866Trp Single submitter ⚠
- p.Arg902Leu Single submitter ⚠
- p.Arg909Cys Single submitter ⚠
- p.Arg909His Single submitter ⚠
- p.Arg92Leu Single submitter ⚠
- p.Arg938Cys Single submitter ⚠
- p.Arg938His Single submitter ⚠
- p.Arg964Cys Single submitter ⚠
- p.Arg995Gln Single submitter ⚠
- p.Arg995Trp Single submitter ⚠
- p.Asn1043Ser Single submitter ⚠
- p.Asn1155Ser Single submitter ⚠
- p.Asn799Lys Single submitter ⚠
- p.Asn94Ser Single submitter ⚠
- p.Asn98His Single submitter ⚠
- p.Asp1062Asn Single submitter ⚠
- p.Asp1085Tyr Single submitter ⚠
- p.Asp1220His Single submitter ⚠
- p.Asp136Tyr Single submitter ⚠
- p.Asp441Glu Single submitter ⚠
- p.Asp52Glu Single submitter ⚠
- p.Asp650Ala Single submitter ⚠
- p.Cys1516Ser Single submitter ⚠
- p.Cys1596Arg Single submitter ⚠
- p.Cys942Tyr Single submitter ⚠
- p.Gln1488Arg Single submitter ⚠
- p.Gln1681His Single submitter ⚠
- p.Gln179Arg Single submitter ⚠
- p.Gln224Leu Single submitter ⚠
- p.Gln564His Single submitter ⚠
- p.Gln762His Single submitter ⚠
- p.Gln877Arg Single submitter ⚠
- p.Glu1014Lys Single submitter ⚠
- p.Glu1018Lys Single submitter ⚠
- p.Glu1074Lys Single submitter ⚠
- p.Glu1083Gly Single submitter ⚠
- p.Glu1121Gly Single submitter ⚠
- p.Glu1160Gly Single submitter ⚠
- p.Glu1191Gln Single submitter ⚠
- p.Glu1311Gly Single submitter ⚠
- p.Glu140Gln Single submitter ⚠
- p.Glu140Gly Single submitter ⚠
- p.Glu1534Asp Single submitter ⚠
- p.Glu1534Lys Single submitter ⚠
- p.Glu1554Lys Single submitter ⚠
- p.Glu1626Lys Single submitter ⚠
- p.Glu213Gly Single submitter ⚠
- p.Glu256Gln Single submitter ⚠
- p.Glu535Lys Single submitter ⚠
- p.Glu630Lys Single submitter ⚠
- p.Glu638Val Single submitter ⚠
- p.Glu642Lys Single submitter ⚠
- p.Glu705Lys Single submitter ⚠
- p.Glu742Lys Single submitter ⚠
- p.Glu817Lys Single submitter ⚠
- p.Glu858Lys Single submitter ⚠
- p.Glu986Lys Single submitter ⚠
- p.Gly1079Arg Single submitter ⚠
- p.Gly1079Glu Single submitter ⚠
- p.Gly1090Val Single submitter ⚠
- p.Gly1138Ser Single submitter ⚠
- p.Gly115Ser Single submitter ⚠
- p.Gly117Asp Single submitter ⚠
- p.Gly1199Ser Single submitter ⚠
- p.Gly1345Arg Single submitter ⚠
- p.Gly1358Asp Single submitter ⚠
- p.Gly1441Arg Single submitter ⚠
- p.Gly1441Asp Single submitter ⚠
- p.Gly1480Arg Single submitter ⚠
- p.Gly1587Arg Single submitter ⚠
- p.Gly205Arg Single submitter ⚠
- p.Gly3Ser Single submitter ⚠
- p.Gly402Asp Single submitter ⚠
- p.Gly402Ser Single submitter ⚠
- p.Gly409Glu Single submitter ⚠
- p.Gly55Ser Single submitter ⚠
- p.Gly681Ser Single submitter ⚠
- p.Gly702Arg Single submitter ⚠
- p.Gly716Arg Single submitter ⚠
- p.Gly838Val Single submitter ⚠
- p.His1024Tyr Single submitter ⚠
- p.His1025Tyr Single submitter ⚠
- p.His1099Gln Single submitter ⚠
- p.His1346Tyr Single submitter ⚠
- p.His1386Asp Single submitter ⚠
- p.His1568Gln Single submitter ⚠
- p.His308Tyr Single submitter ⚠
- p.His334Gln Single submitter ⚠
- p.His601Leu Single submitter ⚠
- p.His606Tyr Single submitter ⚠
- p.His803Tyr Single submitter ⚠
- p.Ile1164Val Single submitter ⚠
- p.Ile291Thr Single submitter ⚠
- p.Leu1001Met Single submitter ⚠
- p.Leu1153Trp Single submitter ⚠
- p.Leu1174Pro Single submitter ⚠
- p.Leu139Arg Single submitter ⚠
- p.Leu19Pro Single submitter ⚠
- p.Leu247Pro Single submitter ⚠
- p.Leu43Met Single submitter ⚠
- p.Leu589Pro Single submitter ⚠
- p.Leu67Val Single submitter ⚠
- p.Lys327Asn Single submitter ⚠
- p.Lys571Arg Single submitter ⚠
- p.Met1347Val Single submitter ⚠
- p.Met610Ile Single submitter ⚠
- p.Met683Thr Single submitter ⚠
- p.Phe1059Leu Single submitter ⚠
- p.Phe278Leu Single submitter ⚠
- p.Phe484Cys Single submitter ⚠
- p.Phe748Leu Single submitter ⚠
- p.Pro1003Thr Single submitter ⚠
- p.Pro1023Arg Single submitter ⚠
- p.Pro1084Ser Single submitter ⚠
- p.Pro1096His Single submitter ⚠
- p.Pro1096Ser Single submitter ⚠
- p.Pro1110Arg Single submitter ⚠
- p.Pro1130Leu Single submitter ⚠
- p.Pro1142Ser Single submitter ⚠
- p.Pro1142Thr Single submitter ⚠
- p.Pro1143Leu Single submitter ⚠
- p.Pro1187Leu Single submitter ⚠
- p.Pro1208Ser Single submitter ⚠
- p.Pro1233Ser Single submitter ⚠
- p.Pro1242Ser Single submitter ⚠
- p.Pro1242Thr Single submitter ⚠
- p.Pro126Thr Single submitter ⚠
- p.Pro1296Ser Single submitter ⚠
- p.Pro1312Ala Single submitter ⚠
- p.Pro1312Arg Single submitter ⚠
- p.Pro1312Leu Single submitter ⚠
- p.Pro1318Thr Single submitter ⚠
- p.Pro1365Ser Single submitter ⚠
- p.Pro1389Arg Single submitter ⚠
- p.Pro1407Ser Single submitter ⚠
- p.Pro1454Ala Single submitter ⚠
- p.Pro1511Arg Single submitter ⚠
- p.Pro1520Leu Single submitter ⚠
- p.Pro1622Leu Single submitter ⚠
- p.Pro1630Arg Single submitter ⚠
- p.Pro1658Leu Single submitter ⚠
- p.Pro172Leu Single submitter ⚠
- p.Pro189Ala Single submitter ⚠
- p.Pro189Leu Single submitter ⚠
- p.Pro286Thr Single submitter ⚠
- p.Pro33Ala Single submitter ⚠
- p.Pro33Ser Single submitter ⚠
- p.Pro353Leu Single submitter ⚠
- p.Pro353Ser Single submitter ⚠
- p.Pro368Leu Single submitter ⚠
- p.Pro593Leu Single submitter ⚠
- p.Pro64Ser Single submitter ⚠
- p.Pro653Thr Single submitter ⚠
- p.Pro782Ser Single submitter ⚠
- p.Pro79Ser Single submitter ⚠
- p.Pro819Leu Single submitter ⚠
- p.Ser1034Leu Single submitter ⚠
- p.Ser1077Tyr Single submitter ⚠
- p.Ser1131Arg Single submitter ⚠
- p.Ser1140Phe Single submitter ⚠
- p.Ser1244Cys Single submitter ⚠
- p.Ser1375Cys Single submitter ⚠
- p.Ser1375Tyr Single submitter ⚠
- p.Ser1381Arg Single submitter ⚠
- p.Ser1642Pro Single submitter ⚠
- p.Ser461Leu Single submitter ⚠
- p.Ser551Leu Single submitter ⚠
- p.Ser605Gly Single submitter ⚠
- p.Ser6Gly Single submitter ⚠
- p.Ser701Asn Single submitter ⚠
- p.Thr1040Asn Single submitter ⚠
- p.Thr1091Ile Single submitter ⚠
- p.Thr1107Ala Single submitter ⚠
- p.Thr1186Ile Single submitter ⚠
- p.Thr1189Asn Single submitter ⚠
- p.Thr1214Ala Single submitter ⚠
- p.Thr1286Ala Single submitter ⚠
- p.Thr1314Ala Single submitter ⚠
- p.Thr1465Ile Single submitter ⚠
- p.Thr1561Ala Single submitter ⚠
- p.Thr1562Ile Single submitter ⚠
- p.Thr1571Met Single submitter ⚠
- p.Thr1599Ile Single submitter ⚠
- p.Thr1625Ile Single submitter ⚠
- p.Thr1648Met Single submitter ⚠
- p.Thr203Ile Single submitter ⚠
- p.Thr385Ile Single submitter ⚠
- p.Thr502Ala Single submitter ⚠
- p.Thr514Pro Single submitter ⚠
- p.Thr618Lys Single submitter ⚠
- p.Thr836Ser Single submitter ⚠
- p.Thr934Ser Single submitter ⚠
- p.Thr988Ala Single submitter ⚠
- p.Thr988Ile Single submitter ⚠
- p.Trp1379Arg Single submitter ⚠
- p.Trp1379Gly Single submitter ⚠
- p.Trp444Cys Single submitter ⚠
- p.Trp946Arg Single submitter ⚠
- p.Tyr1065His Single submitter ⚠
- p.Tyr435Cys Single submitter ⚠
- p.Tyr478His Single submitter ⚠
- p.Tyr60Asn Single submitter ⚠
- p.Tyr60Cys Single submitter ⚠
- p.Val1257Ala Single submitter ⚠
- p.Val1257Met Single submitter ⚠
- p.Val1287Gly Single submitter ⚠
- p.Val1287Ile Single submitter ⚠
- p.Val1305Ile Single submitter ⚠
- p.Val1487Met Single submitter ⚠