Sugi Variant

Sugi Variant/ADCY10

ADCY10 — 669 ClinVar variants

All ClinVar germline ADCY10 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 320 flagged for review →

20 Pathogenic · 2 Pathogenic/Likely pathogenic · 12 Likely pathogenic · 12 Conflicting · 121 Benign · 20 Benign/Likely benign · 160 Likely benign · 322 Uncertain significance

Full ADCY10 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 320

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 10

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 199

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 199

Predictors split 111

The independent predictors disagree with each other — read with care.

All ADCY10 variants

Pathogenic 20

Pathogenic/Likely pathogenic 2

Likely pathogenic 12

Conflicting classifications of pathogenicity 12

Benign 121

Benign/Likely benign 20

Likely benign 160

Uncertain significance 322

Showing the top 300 by review status; the full set is in the sitemap.