ADGRL3 — 149 ClinVar variants

All ClinVar germline ADGRL3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

4 Likely benign · 145 Uncertain significance

Full ADGRL3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All ADGRL3 variants

Likely benign 4

p.Ala225= Single submitter
p.Asp546= Single submitter
p.Ser1142Ter Single submitter
p.Ser491Pro Single submitter

Uncertain significance 145

p.Ala1007Val Single submitter
p.Ala1068Ser Single submitter
p.Ala1460Thr Single submitter
p.Ala1464Thr Single submitter
p.Ala310Thr Single submitter
p.Ala372Thr Single submitter
p.Ala705Val Single submitter
p.Ala745Gly Single submitter
p.Ala87Gly Single submitter
p.Arg1001Gln Single submitter
p.Arg112Cys Single submitter
p.Arg1243Cys Single submitter
p.Arg1320Gly Single submitter
p.Arg1351Cys Single submitter
p.Arg1423Gln Single submitter
p.Arg513Trp Single submitter
p.Arg580His Single submitter
p.Arg661Gln Single submitter
p.Arg675Leu Single submitter
p.Arg732Cys Single submitter
p.Arg894His Single submitter
p.Arg906Gln Single submitter
p.Arg977Cys Single submitter
p.Arg99His Single submitter
p.Asn1313Ser Single submitter
p.Asn1499His Single submitter
p.Asn624Ser Single submitter
p.Asn817Lys Single submitter
p.Asn818Ser Single submitter
p.Asp1486Asn Single submitter
p.Asp220Gly Single submitter
p.Asp546Gly Single submitter
p.Asp614Glu Single submitter
p.Asp976Asn Single submitter
p.Cys134Tyr Single submitter
p.Cys1481Gly Single submitter
p.Cys917Tyr Single submitter
p.Gln558Pro Single submitter
p.Glu1042Val Single submitter
p.Glu1387Lys Single submitter
p.Glu1439Lys Single submitter
p.Glu1530Lys Single submitter
p.Glu826Lys Single submitter
p.Gly1221Ser Single submitter
p.Gly1368Cys Single submitter
p.Gly1496Asp Single submitter
p.Gly1517Val Single submitter
p.Gly502Arg Single submitter
p.Gly582Glu Single submitter
p.His1209Arg Single submitter
p.His1209Pro Single submitter
p.His1418Pro Single submitter
p.His1440Pro Single submitter
p.His1502Arg Single submitter
p.His18Arg Single submitter
p.His272Pro Single submitter
p.His470Tyr Single submitter
p.His789Leu Single submitter
p.His841Asn Single submitter
p.His914Tyr Single submitter
p.Ile1187Val Single submitter
p.Ile1220Thr Single submitter
p.Ile1376Val Single submitter
p.Ile260Val Single submitter
p.Ile594Thr Single submitter
p.Ile594Val Single submitter
p.Ile626Val Single submitter
p.Ile986Ser Single submitter
p.Leu1334Pro Single submitter
p.Leu1367Phe Single submitter
p.Leu1394Phe Single submitter
p.Leu301Met Single submitter
p.Leu552Pro Single submitter
p.Leu643Val Single submitter
p.Leu994Val Single submitter
p.Lys1122fs Single submitter
p.Lys1490Glu Single submitter
p.Lys417Asn Single submitter
p.Lys629Gln Single submitter
p.Lys873Arg Single submitter
p.Met10Ile Single submitter
p.Met1101Val Single submitter
p.Met120Val Single submitter
p.Met575Val Single submitter
p.Met706Thr Single submitter
p.Met736Val Single submitter
p.Met830Val Single submitter
p.Phe1027Leu Single submitter
p.Pro1005Ala Single submitter
p.Pro1059Leu Single submitter
p.Pro1231Ser Single submitter
p.Pro1406Ala Single submitter
p.Pro1406Ser Single submitter
p.Pro1457Leu Single submitter
p.Pro1478Ser Single submitter
p.Pro177Leu Single submitter
p.Pro360Ala Single submitter
p.Pro884Arg Single submitter
p.Ser1066Leu Single submitter
p.Ser1235Thr Single submitter
p.Ser1429Arg Single submitter
p.Ser1471Asn Single submitter
p.Ser1471Thr Single submitter
p.Ser1514Gly Single submitter
p.Ser464Ile Single submitter
p.Ser491Cys Single submitter
p.Ser505Asn Single submitter
p.Ser528Thr Single submitter
p.Ser536Gly Single submitter
p.Ser536Ile Single submitter
p.Ser556Leu Single submitter
p.Ser565Gly Single submitter
p.Ser824Phe Single submitter
p.Ser829Asn Single submitter
p.Ser975Gly Single submitter
p.Thr1169Ala Single submitter
p.Thr1236Ala Single submitter
p.Thr1236Pro Single submitter
p.Thr1287Ser Single submitter
p.Thr243Ser Single submitter
p.Thr265Ala Single submitter
p.Thr508Ser Single submitter
p.Thr516Ala Single submitter
p.Thr516Asn Single submitter
p.Thr825Ala Single submitter
p.Thr834Met Single submitter
p.Thr902Ser Single submitter
p.Thr915Ala Single submitter
p.Thr916Ala Single submitter
p.Thr916Ser Single submitter
p.Tyr1133Cys Single submitter
p.Tyr1202Cys Single submitter
p.Tyr1322Cys Single submitter
p.Tyr1345Cys Single submitter
p.Tyr1409His Single submitter
p.Tyr1409Ser Single submitter
p.Val1170Gly Single submitter
p.Val1250Ile Single submitter
p.Val1315Gly Single submitter
p.Val1501Ile Single submitter
p.Val274Ala Single submitter
p.Val769Ala Single submitter
p.Val843Ile Single submitter
p.Val849Ile Single submitter
p.Val940Ala Single submitter