Sugi Variant

Sugi Variant/AGMO

AGMO — 151 ClinVar variants

All ClinVar germline AGMO variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 106 flagged for review →

2 Pathogenic · 3 Likely pathogenic · 2 Conflicting · 11 Benign · 1 Benign/Likely benign · 10 Likely benign · 122 Uncertain significance

Full AGMO gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 106

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 1

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 84

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

Predictors split 21

The independent predictors disagree with each other — read with care.

All AGMO variants

Pathogenic 2

Likely pathogenic 3

Conflicting classifications of pathogenicity 2

Benign 11

Benign/Likely benign 1

Likely benign 10

Uncertain significance 122