Sugi Variant

Sugi Variant/ANKRD1

ANKRD1 — 565 ClinVar variants

All ClinVar germline ANKRD1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 249 flagged for review →

33 Conflicting · 22 Benign · 27 Benign/Likely benign · 161 Likely benign · 322 Uncertain significance

Full ANKRD1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 249

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 13

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 137

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

Predictors split 99

The independent predictors disagree with each other — read with care.

All ANKRD1 variants

Conflicting classifications of pathogenicity 33

Benign 22

Benign/Likely benign 27

Likely benign 161

Uncertain significance 322

Showing the top 300 by review status; the full set is in the sitemap.