ANKRD29 — 55 ClinVar variants
All ClinVar germline ANKRD29 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 46 flagged for review →
2 Likely benign · 53 Uncertain significance
Full ANKRD29 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 46
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 41
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ANKRD29 p.Ala185Pro Uncertain significance Single submitter
- ANKRD29 p.Ala249Val Uncertain significance Single submitter
- ANKRD29 p.Ala260Val Uncertain significance Single submitter
- ANKRD29 p.Ala280Thr Uncertain significance Single submitter
- ANKRD29 p.Ala280Val Uncertain significance Single submitter
- ANKRD29 p.Arg204His Uncertain significance Single submitter
- ANKRD29 p.Arg22Lys Uncertain significance Single submitter
- ANKRD29 p.Arg290His Uncertain significance Single submitter
- ANKRD29 p.Arg36Gln Uncertain significance Single submitter
- ANKRD29 p.Arg3Lys Uncertain significance Single submitter
- ANKRD29 p.Asn14Asp Uncertain significance Single submitter
- ANKRD29 p.Asn255Ser Uncertain significance Single submitter
- ANKRD29 p.Asn73Ile Uncertain significance Single submitter
- ANKRD29 p.Asn92Lys Uncertain significance Single submitter
- ANKRD29 p.Asp225Ala Uncertain significance Single submitter
- ANKRD29 p.Gln88Lys Uncertain significance Single submitter
- ANKRD29 p.Glu229Lys Uncertain significance Single submitter
- ANKRD29 p.Glu264Ala Uncertain significance Single submitter
- ANKRD29 p.Glu77Gly Uncertain significance Single submitter
- ANKRD29 p.Glu77Val Uncertain significance Single submitter
- ANKRD29 p.Gly156Val Uncertain significance Single submitter
- ANKRD29 p.Gly178Val Uncertain significance Single submitter
- ANKRD29 p.Gly238Ala Uncertain significance Single submitter
- ANKRD29 p.His91Arg Uncertain significance Single submitter
- ANKRD29 p.Ile256Val Uncertain significance Single submitter
- ANKRD29 p.Ile72Val Uncertain significance Single submitter
- ANKRD29 p.Leu215Ile Uncertain significance Single submitter
- ANKRD29 p.Leu230Phe Uncertain significance Single submitter
- ANKRD29 p.Leu237Val Uncertain significance Single submitter
- ANKRD29 p.Leu291Phe Uncertain significance Single submitter
- ANKRD29 p.Lys170Glu Uncertain significance Single submitter
- ANKRD29 p.Pro174Ser Uncertain significance Single submitter
- ANKRD29 p.Pro279Ala Uncertain significance Single submitter
- ANKRD29 p.Ser167Leu Uncertain significance Single submitter
- ANKRD29 p.Ser191Gly Uncertain significance Single submitter
- ANKRD29 p.Ser253Gly Uncertain significance Single submitter
- ANKRD29 p.Ser270Tyr Uncertain significance Single submitter
- ANKRD29 p.Tyr55Cys Uncertain significance Single submitter
- ANKRD29 p.Val37Met Uncertain significance Single submitter
- ANKRD29 p.Val94Ile Uncertain significance Single submitter
- ANKRD29 p.Val95Met Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All ANKRD29 variants
Likely benign 2
- p.Asp203Glu Single submitter
- p.Tyr55= Single submitter
Uncertain significance 53
- p.Ala103Thr Single submitter
- p.Ala185Pro Single submitter ⚠
- p.Ala202Val Single submitter
- p.Ala249Val Single submitter ⚠
- p.Ala260Val Single submitter ⚠
- p.Ala280Thr Single submitter ⚠
- p.Ala280Val Single submitter ⚠
- p.Arg200Gly Single submitter
- p.Arg204His Single submitter ⚠
- p.Arg22Lys Single submitter ⚠
- p.Arg290His Single submitter ⚠
- p.Arg36Gln Single submitter ⚠
- p.Arg36Trp Single submitter
- p.Arg3Lys Single submitter ⚠
- p.Arg76Thr Single submitter ⚠
- p.Asn14Asp Single submitter ⚠
- p.Asn255Ser Single submitter ⚠
- p.Asn73Ile Single submitter ⚠
- p.Asn92Lys Single submitter ⚠
- p.Asp225Ala Single submitter ⚠
- p.Asp38Val Single submitter
- p.Gln88Lys Single submitter ⚠
- p.Glu229Lys Single submitter ⚠
- p.Glu264Ala Single submitter ⚠
- p.Glu264Val Single submitter
- p.Glu77Gly Single submitter ⚠
- p.Glu77Val Single submitter ⚠
- p.Gly102Ala Single submitter ⚠
- p.Gly156Val Single submitter ⚠
- p.Gly178Val Single submitter ⚠
- p.Gly238Ala Single submitter ⚠
- p.Gly254Arg Single submitter
- p.His91Arg Single submitter ⚠
- p.Ile256Val Single submitter ⚠
- p.Ile288Met Single submitter ⚠
- p.Ile72Val Single submitter ⚠
- p.Leu215Ile Single submitter ⚠
- p.Leu230Phe Single submitter ⚠
- p.Leu237Val Single submitter ⚠
- p.Leu291Phe Single submitter ⚠
- p.Lys170Glu Single submitter ⚠
- p.Phe233Leu Single submitter ⚠
- p.Pro174Ser Single submitter ⚠
- p.Pro279Ala Single submitter ⚠
- p.Ser167Leu Single submitter ⚠
- p.Ser191Gly Single submitter ⚠
- p.Ser253Gly Single submitter ⚠
- p.Ser270Tyr Single submitter ⚠
- p.Tyr122Asp Single submitter ⚠
- p.Tyr55Cys Single submitter ⚠
- p.Val37Met Single submitter ⚠
- p.Val94Ile Single submitter ⚠
- p.Val95Met Single submitter ⚠