ANKRD37 — 23 ClinVar variants
All ClinVar germline ANKRD37 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 22 flagged for review →
1 Likely benign · 22 Uncertain significance
Full ANKRD37 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 22
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 21
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ANKRD37 p.Ala104Thr Uncertain significance Single submitter
- ANKRD37 p.Ala44Thr Uncertain significance Single submitter
- ANKRD37 p.Arg133Lys Uncertain significance Single submitter
- ANKRD37 p.Asp111Gly Uncertain significance Single submitter
- ANKRD37 p.Asp87Gly Uncertain significance Single submitter
- ANKRD37 p.Cys121Arg Uncertain significance Single submitter
- ANKRD37 p.Glu18Asp Uncertain significance Single submitter
- ANKRD37 p.Gly40Arg Uncertain significance Single submitter
- ANKRD37 p.Gly97Arg Uncertain significance Single submitter
- ANKRD37 p.Gly97Trp Uncertain significance Single submitter
- ANKRD37 p.Leu2Gln Uncertain significance Single submitter
- ANKRD37 p.Leu2Val Uncertain significance Single submitter
- ANKRD37 p.Met122Val Uncertain significance Single submitter
- ANKRD37 p.Pro27Leu Uncertain significance Single submitter
- ANKRD37 p.Pro29Leu Uncertain significance Single submitter
- ANKRD37 p.Ser41Arg Uncertain significance Single submitter
- ANKRD37 p.Thr117Arg Uncertain significance Single submitter
- ANKRD37 p.Trp105Ser Uncertain significance Single submitter
- ANKRD37 p.Val139Met Uncertain significance Single submitter
- ANKRD37 p.Val149Ile Uncertain significance Single submitter
- ANKRD37 p.Val74Ile Uncertain significance Single submitter
Predictors split 1
The independent predictors disagree with each other — read with care.
All ANKRD37 variants
Likely benign 1
- p.Asn134Asp Single submitter
Uncertain significance 22
- p.Ala104Thr Single submitter ⚠
- p.Ala44Thr Single submitter ⚠
- p.Ala88Asp Single submitter ⚠
- p.Arg133Lys Single submitter ⚠
- p.Asp111Gly Single submitter ⚠
- p.Asp87Gly Single submitter ⚠
- p.Cys121Arg Single submitter ⚠
- p.Glu18Asp Single submitter ⚠
- p.Gly40Arg Single submitter ⚠
- p.Gly97Arg Single submitter ⚠
- p.Gly97Trp Single submitter ⚠
- p.Leu2Gln Single submitter ⚠
- p.Leu2Val Single submitter ⚠
- p.Met122Val Single submitter ⚠
- p.Pro27Leu Single submitter ⚠
- p.Pro29Leu Single submitter ⚠
- p.Ser41Arg Single submitter ⚠
- p.Thr117Arg Single submitter ⚠
- p.Trp105Ser Single submitter ⚠
- p.Val139Met Single submitter ⚠
- p.Val149Ile Single submitter ⚠
- p.Val74Ile Single submitter ⚠