ANKRD9 — 60 ClinVar variants
All ClinVar germline ANKRD9 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 60 flagged for review →
60 Uncertain significance
Full ANKRD9 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 60
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 32
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ANKRD9 p.Ala105Pro Uncertain significance Single submitter
- ANKRD9 p.Ala214Thr Uncertain significance Single submitter
- ANKRD9 p.Ala280Ser Uncertain significance Single submitter
- ANKRD9 p.Ala289Thr Uncertain significance Single submitter
- ANKRD9 p.Ala40Thr Uncertain significance Single submitter
- ANKRD9 p.Arg125Gly Uncertain significance Single submitter
- ANKRD9 p.Arg130Gly Uncertain significance Single submitter
- ANKRD9 p.Arg130Leu Uncertain significance Single submitter
- ANKRD9 p.Arg131Cys Uncertain significance Single submitter
- ANKRD9 p.Arg155Leu Uncertain significance Single submitter
- ANKRD9 p.Arg54Ser Uncertain significance Single submitter
- ANKRD9 p.Asp13Gly Uncertain significance Single submitter
- ANKRD9 p.Asp43His Uncertain significance Single submitter
- ANKRD9 p.Asp4Glu Uncertain significance Single submitter
- ANKRD9 p.Gln226Arg Uncertain significance Single submitter
- ANKRD9 p.Glu197Gln Uncertain significance Single submitter
- ANKRD9 p.Glu264Gly Uncertain significance Single submitter
- ANKRD9 p.Gly106Ser Uncertain significance Single submitter
- ANKRD9 p.Gly182Ser Uncertain significance Single submitter
- ANKRD9 p.Gly222Arg Uncertain significance Single submitter
- ANKRD9 p.Gly245Ala Uncertain significance Single submitter
- ANKRD9 p.Gly317Asp Uncertain significance Single submitter
- ANKRD9 p.Leu100Phe Uncertain significance Single submitter
- ANKRD9 p.Leu129Arg Uncertain significance Single submitter
- ANKRD9 p.Leu163Pro Uncertain significance Single submitter
- ANKRD9 p.Leu313Val Uncertain significance Single submitter
- ANKRD9 p.Leu44Met Uncertain significance Single submitter
- ANKRD9 p.Leu91Gln Uncertain significance Single submitter
- ANKRD9 p.Met53Thr Uncertain significance Single submitter
- ANKRD9 p.Pro305Leu Uncertain significance Single submitter
- ANKRD9 p.Ser212Pro Uncertain significance Single submitter
- ANKRD9 p.Thr94Ala Uncertain significance Single submitter
Predictors split 28
The independent predictors disagree with each other — read with care.
- ANKRD9 p.Ala111Val Uncertain significance Single submitter
- ANKRD9 p.Ala12Val Uncertain significance Single submitter
- ANKRD9 p.Ala170Thr Uncertain significance Single submitter
- ANKRD9 p.Arg125Cys Uncertain significance Single submitter
- ANKRD9 p.Arg144Trp Uncertain significance Single submitter
- ANKRD9 p.Arg227Cys Uncertain significance Single submitter
- ANKRD9 p.Arg23Cys Uncertain significance Single submitter
- ANKRD9 p.Arg23Ser Uncertain significance Single submitter
- ANKRD9 p.Arg257His Uncertain significance Single submitter
- ANKRD9 p.Arg294Cys Uncertain significance Single submitter
- ANKRD9 p.Arg31Cys Uncertain significance Single submitter
- ANKRD9 p.Arg64His Uncertain significance Single submitter
- ANKRD9 p.Asp312Val Uncertain significance Single submitter
- ANKRD9 p.Glu142Gln Uncertain significance Single submitter
- ANKRD9 p.Glu142Lys Uncertain significance Single submitter
- ANKRD9 p.Glu17Lys Uncertain significance Single submitter
- ANKRD9 p.Gly159Ser Uncertain significance Single submitter
- ANKRD9 p.Gly222Trp Uncertain significance Single submitter
- ANKRD9 p.Gly253Asp Uncertain significance Single submitter
- ANKRD9 p.Leu196Phe Uncertain significance Single submitter
- ANKRD9 p.Met283Thr Uncertain significance Single submitter
- ANKRD9 p.Phe35Leu Uncertain significance Single submitter
- ANKRD9 p.Pro140Gln Uncertain significance Single submitter
- ANKRD9 p.Pro172Ser Uncertain significance Single submitter
- ANKRD9 p.Pro303Leu Uncertain significance Single submitter
- ANKRD9 p.Thr135Asn Uncertain significance Single submitter
- ANKRD9 p.Thr135Ser Uncertain significance Single submitter
- ANKRD9 p.Thr194Met Uncertain significance Single submitter
All ANKRD9 variants
Uncertain significance 60
- p.Ala105Pro Single submitter ⚠
- p.Ala111Val Single submitter ⚠
- p.Ala12Val Single submitter ⚠
- p.Ala170Thr Single submitter ⚠
- p.Ala214Thr Single submitter ⚠
- p.Ala280Ser Single submitter ⚠
- p.Ala289Thr Single submitter ⚠
- p.Ala40Thr Single submitter ⚠
- p.Arg125Cys Single submitter ⚠
- p.Arg125Gly Single submitter ⚠
- p.Arg130Gly Single submitter ⚠
- p.Arg130Leu Single submitter ⚠
- p.Arg131Cys Single submitter ⚠
- p.Arg144Trp Single submitter ⚠
- p.Arg155Leu Single submitter ⚠
- p.Arg227Cys Single submitter ⚠
- p.Arg23Cys Single submitter ⚠
- p.Arg23Ser Single submitter ⚠
- p.Arg257His Single submitter ⚠
- p.Arg294Cys Single submitter ⚠
- p.Arg31Cys Single submitter ⚠
- p.Arg54Ser Single submitter ⚠
- p.Arg64His Single submitter ⚠
- p.Asp13Gly Single submitter ⚠
- p.Asp312Val Single submitter ⚠
- p.Asp43His Single submitter ⚠
- p.Asp4Glu Single submitter ⚠
- p.Gln226Arg Single submitter ⚠
- p.Glu142Gln Single submitter ⚠
- p.Glu142Lys Single submitter ⚠
- p.Glu17Lys Single submitter ⚠
- p.Glu197Gln Single submitter ⚠
- p.Glu264Gly Single submitter ⚠
- p.Gly106Ser Single submitter ⚠
- p.Gly159Ser Single submitter ⚠
- p.Gly182Ser Single submitter ⚠
- p.Gly222Arg Single submitter ⚠
- p.Gly222Trp Single submitter ⚠
- p.Gly245Ala Single submitter ⚠
- p.Gly253Asp Single submitter ⚠
- p.Gly317Asp Single submitter ⚠
- p.Leu100Phe Single submitter ⚠
- p.Leu129Arg Single submitter ⚠
- p.Leu163Pro Single submitter ⚠
- p.Leu196Phe Single submitter ⚠
- p.Leu313Val Single submitter ⚠
- p.Leu44Met Single submitter ⚠
- p.Leu91Gln Single submitter ⚠
- p.Met283Thr Single submitter ⚠
- p.Met53Thr Single submitter ⚠
- p.Phe35Leu Single submitter ⚠
- p.Pro140Gln Single submitter ⚠
- p.Pro172Ser Single submitter ⚠
- p.Pro303Leu Single submitter ⚠
- p.Pro305Leu Single submitter ⚠
- p.Ser212Pro Single submitter ⚠
- p.Thr135Asn Single submitter ⚠
- p.Thr135Ser Single submitter ⚠
- p.Thr194Met Single submitter ⚠
- p.Thr94Ala Single submitter ⚠