ANO2 — 6 ClinVar variants
All ClinVar germline ANO2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 1 flagged for review →
2 Benign · 4 Likely benign
Full ANO2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 1
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All ANO2 variants
Benign 2
- c.1435-244C>T Multiple submitters ⚠
- p.Ile547Val Single submitter
Likely benign 4
- c.785+6T>A Single submitter
- p.Arg89His Single submitter
- p.Gly966= Single submitter
- p.Pro825Leu Single submitter