ANP32D — 24 ClinVar variants
All ClinVar germline ANP32D variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 24 flagged for review →
24 Uncertain significance
Full ANP32D gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 24
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 6
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ANP32D p.Asn129Ser Uncertain significance Single submitter
- ANP32D p.Asp18Asn Uncertain significance Single submitter
- ANP32D p.Leu128Gln Uncertain significance Single submitter
- ANP32D p.Leu34Met Uncertain significance Single submitter
- ANP32D p.Lys5Arg Uncertain significance Single submitter
- ANP32D p.Thr15Lys Uncertain significance Single submitter
Predictors split 18
The independent predictors disagree with each other — read with care.
- ANP32D p.Arg14Gly Uncertain significance Single submitter
- ANP32D p.Arg14Ser Uncertain significance Single submitter
- ANP32D p.Asn127Ile Uncertain significance Single submitter
- ANP32D p.Asn51Ile Uncertain significance Single submitter
- ANP32D p.Glu43Lys Uncertain significance Single submitter
- ANP32D p.Gly32Cys Uncertain significance Single submitter
- ANP32D p.His92Arg Uncertain significance Single submitter
- ANP32D p.Leu103Phe Uncertain significance Single submitter
- ANP32D p.Leu54Phe Uncertain significance Single submitter
- ANP32D p.Leu69Ile Uncertain significance Single submitter
- ANP32D p.Leu83Met Uncertain significance Single submitter
- ANP32D p.Lys20Arg Uncertain significance Single submitter
- ANP32D p.Met3Thr Uncertain significance Single submitter
- ANP32D p.Phe121Ile Uncertain significance Single submitter
- ANP32D p.Phe41Ser Uncertain significance Single submitter
- ANP32D p.Pro61Ser Uncertain significance Single submitter
- ANP32D p.Pro61Thr Uncertain significance Single submitter
- ANP32D p.Thr38Ala Uncertain significance Single submitter
All ANP32D variants
Uncertain significance 24
- p.Arg14Gly Single submitter ⚠
- p.Arg14Ser Single submitter ⚠
- p.Asn127Ile Single submitter ⚠
- p.Asn129Ser Single submitter ⚠
- p.Asn51Ile Single submitter ⚠
- p.Asp18Asn Single submitter ⚠
- p.Glu43Lys Single submitter ⚠
- p.Gly32Cys Single submitter ⚠
- p.His92Arg Single submitter ⚠
- p.Leu103Phe Single submitter ⚠
- p.Leu128Gln Single submitter ⚠
- p.Leu34Met Single submitter ⚠
- p.Leu54Phe Single submitter ⚠
- p.Leu69Ile Single submitter ⚠
- p.Leu83Met Single submitter ⚠
- p.Lys20Arg Single submitter ⚠
- p.Lys5Arg Single submitter ⚠
- p.Met3Thr Single submitter ⚠
- p.Phe121Ile Single submitter ⚠
- p.Phe41Ser Single submitter ⚠
- p.Pro61Ser Single submitter ⚠
- p.Pro61Thr Single submitter ⚠
- p.Thr15Lys Single submitter ⚠
- p.Thr38Ala Single submitter ⚠