ANTKMT — 62 ClinVar variants
All ClinVar germline ANTKMT variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 59 flagged for review →
4 Likely benign · 58 Uncertain significance
Full ANTKMT gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 59
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 24
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ANTKMT p.Ala209Ser Uncertain significance Single submitter
- ANTKMT p.Ala224Asp Uncertain significance Single submitter
- ANTKMT p.Ala224Ser Uncertain significance Single submitter
- ANTKMT p.Ala62Ser Uncertain significance Single submitter
- ANTKMT p.Ala9Val Uncertain significance Single submitter
- ANTKMT p.Arg212Gln Uncertain significance Single submitter
- ANTKMT p.Glu105Gln Uncertain significance Single submitter
- ANTKMT p.Gly103Asp Uncertain significance Single submitter
- ANTKMT p.Gly206Glu Uncertain significance Single submitter
- ANTKMT p.Gly220Arg Uncertain significance Single submitter
- ANTKMT p.Gly229Val Uncertain significance Single submitter
- ANTKMT p.Gly83Asp Uncertain significance Single submitter
- ANTKMT p.Ile226Thr Uncertain significance Single submitter
- ANTKMT p.Leu178Phe Uncertain significance Single submitter
- ANTKMT p.Leu21Pro Uncertain significance Single submitter
- ANTKMT p.Leu24Val Uncertain significance Single submitter
- ANTKMT p.Phe46Ser Uncertain significance Single submitter
- ANTKMT p.Pro155Arg Uncertain significance Single submitter
- ANTKMT p.Pro221Ala Uncertain significance Single submitter
- ANTKMT p.Pro221Leu Uncertain significance Single submitter
- ANTKMT p.Pro221Ser Uncertain significance Single submitter
- ANTKMT p.Pro227Arg Uncertain significance Single submitter
- ANTKMT p.Tyr197His Uncertain significance Single submitter
- ANTKMT p.Val90Met Uncertain significance Single submitter
Predictors split 35
The independent predictors disagree with each other — read with care.
- ANTKMT p.Ala169Thr Uncertain significance Single submitter
- ANTKMT p.Ala196Ser Uncertain significance Single submitter
- ANTKMT p.Ala36Thr Uncertain significance Single submitter
- ANTKMT p.Ala92Val Uncertain significance Single submitter
- ANTKMT p.Ala93Val Uncertain significance Single submitter
- ANTKMT p.Ala9Thr Uncertain significance Single submitter
- ANTKMT p.Arg130Pro Uncertain significance Single submitter
- ANTKMT p.Arg131Cys Uncertain significance Single submitter
- ANTKMT p.Arg143Cys Uncertain significance Single submitter
- ANTKMT p.Arg143His Likely benign Single submitter
- ANTKMT p.Arg143Ser Uncertain significance Single submitter
- ANTKMT p.Arg170Leu Uncertain significance Single submitter
- ANTKMT p.Arg17Gln Uncertain significance Single submitter
- ANTKMT p.Arg212Trp Uncertain significance Single submitter
- ANTKMT p.Arg52Pro Uncertain significance Single submitter
- ANTKMT p.Arg63Pro Uncertain significance Single submitter
- ANTKMT p.Arg95Ser Uncertain significance Single submitter
- ANTKMT p.Cys123Tyr Uncertain significance Single submitter
- ANTKMT p.Gly125Cys Uncertain significance Single submitter
- ANTKMT p.Gly168Glu Uncertain significance Single submitter
- ANTKMT p.Gly206Trp Uncertain significance Single submitter
- ANTKMT p.Gly97Ser Uncertain significance Single submitter
- ANTKMT p.His117Tyr Uncertain significance Single submitter
- ANTKMT p.Leu165Val Uncertain significance Single submitter
- ANTKMT p.Pro100Arg Uncertain significance Single submitter
- ANTKMT p.Pro151Ser Uncertain significance Single submitter
- ANTKMT p.Pro179Ser Uncertain significance Single submitter
- ANTKMT p.Pro183His Uncertain significance Single submitter
- ANTKMT p.Ser146Pro Uncertain significance Single submitter
- ANTKMT p.Ser173Cys Uncertain significance Single submitter
- ANTKMT p.Ser232Cys Uncertain significance Single submitter
- ANTKMT p.Ser235Asn Uncertain significance Single submitter
- ANTKMT p.Thr185Pro Uncertain significance Single submitter
- ANTKMT p.Tyr129Cys Uncertain significance Single submitter
- ANTKMT p.Tyr35His Uncertain significance Single submitter
All ANTKMT variants
Likely benign 4
- p.Ala186Val Single submitter
- p.Ala26Val Single submitter
- p.Arg143His Single submitter ⚠
- p.Val187Ala Single submitter
Uncertain significance 58
- p.Ala169Thr Single submitter ⚠
- p.Ala196Ser Single submitter ⚠
- p.Ala209Ser Single submitter ⚠
- p.Ala224Asp Single submitter ⚠
- p.Ala224Ser Single submitter ⚠
- p.Ala36Thr Single submitter ⚠
- p.Ala62Ser Single submitter ⚠
- p.Ala92Val Single submitter ⚠
- p.Ala93Val Single submitter ⚠
- p.Ala9Thr Single submitter ⚠
- p.Ala9Val Single submitter ⚠
- p.Arg130Pro Single submitter ⚠
- p.Arg131Cys Single submitter ⚠
- p.Arg143Cys Single submitter ⚠
- p.Arg143Ser Single submitter ⚠
- p.Arg170Leu Single submitter ⚠
- p.Arg17Gln Single submitter ⚠
- p.Arg212Gln Single submitter ⚠
- p.Arg212Trp Single submitter ⚠
- p.Arg52Pro Single submitter ⚠
- p.Arg63Pro Single submitter ⚠
- p.Arg95Ser Single submitter ⚠
- p.Cys123Tyr Single submitter ⚠
- p.Glu105Gln Single submitter ⚠
- p.Gly103Asp Single submitter ⚠
- p.Gly125Cys Single submitter ⚠
- p.Gly168Glu Single submitter ⚠
- p.Gly206Glu Single submitter ⚠
- p.Gly206Trp Single submitter ⚠
- p.Gly220Arg Single submitter ⚠
- p.Gly229Val Single submitter ⚠
- p.Gly83Asp Single submitter ⚠
- p.Gly97Ser Single submitter ⚠
- p.His117Tyr Single submitter ⚠
- p.Ile226Thr Single submitter ⚠
- p.Leu165Val Single submitter ⚠
- p.Leu178Phe Single submitter ⚠
- p.Leu21Pro Single submitter ⚠
- p.Leu24Val Single submitter ⚠
- p.Phe46Ser Single submitter ⚠
- p.Pro100Arg Single submitter ⚠
- p.Pro151Ser Single submitter ⚠
- p.Pro155Arg Single submitter ⚠
- p.Pro179Ser Single submitter ⚠
- p.Pro183His Single submitter ⚠
- p.Pro221Ala Single submitter ⚠
- p.Pro221Leu Single submitter ⚠
- p.Pro221Ser Single submitter ⚠
- p.Pro227Arg Single submitter ⚠
- p.Ser146Pro Single submitter ⚠
- p.Ser173Cys Single submitter ⚠
- p.Ser232Cys Single submitter ⚠
- p.Ser235Asn Single submitter ⚠
- p.Thr185Pro Single submitter ⚠
- p.Tyr129Cys Single submitter ⚠
- p.Tyr197His Single submitter ⚠
- p.Tyr35His Single submitter ⚠
- p.Val90Met Single submitter ⚠