ANXA2R — 29 ClinVar variants
All ClinVar germline ANXA2R variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 29 flagged for review →
29 Uncertain significance
Full ANXA2R gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 29
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 27
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ANXA2R p.Ala110Val Uncertain significance Single submitter
- ANXA2R p.Ala12Asp Uncertain significance Single submitter
- ANXA2R p.Ala12Pro Uncertain significance Single submitter
- ANXA2R p.Ala12Thr Uncertain significance Single submitter
- ANXA2R p.Arg115Thr Uncertain significance Single submitter
- ANXA2R p.Asp131Asn Uncertain significance Single submitter
- ANXA2R p.Asp140Asn Uncertain significance Single submitter
- ANXA2R p.Gln23Glu Uncertain significance Single submitter
- ANXA2R p.Glu21Ala Uncertain significance Single submitter
- ANXA2R p.Ile27Val Uncertain significance Single submitter
- ANXA2R p.Leu116Pro Uncertain significance Single submitter
- ANXA2R p.Leu118Pro Uncertain significance Single submitter
- ANXA2R p.Leu145Val Uncertain significance Single submitter
- ANXA2R p.Leu166Val Uncertain significance Single submitter
- ANXA2R p.Phe174Ile Uncertain significance Single submitter
- ANXA2R p.Pro113Leu Uncertain significance Single submitter
- ANXA2R p.Pro129Leu Uncertain significance Single submitter
- ANXA2R p.Pro150Leu Uncertain significance Single submitter
- ANXA2R p.Pro151Ser Uncertain significance Single submitter
- ANXA2R p.Pro37Thr Uncertain significance Single submitter
- ANXA2R p.Pro39Ser Uncertain significance Single submitter
- ANXA2R p.Pro65Ser Uncertain significance Single submitter
- ANXA2R p.Pro88Ser Uncertain significance Single submitter
- ANXA2R p.Ser125Gly Uncertain significance Single submitter
- ANXA2R p.Ser84Gly Uncertain significance Single submitter
- ANXA2R p.Thr136Ala Uncertain significance Single submitter
- ANXA2R p.Val138Gly Uncertain significance Single submitter
Predictors split 2
The independent predictors disagree with each other — read with care.
All ANXA2R variants
Uncertain significance 29
- p.Ala110Val Single submitter ⚠
- p.Ala12Asp Single submitter ⚠
- p.Ala12Pro Single submitter ⚠
- p.Ala12Thr Single submitter ⚠
- p.Arg115Thr Single submitter ⚠
- p.Asp131Asn Single submitter ⚠
- p.Asp140Asn Single submitter ⚠
- p.Gln23Glu Single submitter ⚠
- p.Glu21Ala Single submitter ⚠
- p.Ile27Val Single submitter ⚠
- p.Leu116Pro Single submitter ⚠
- p.Leu118Pro Single submitter ⚠
- p.Leu145Val Single submitter ⚠
- p.Leu166Pro Single submitter ⚠
- p.Leu166Val Single submitter ⚠
- p.Phe174Ile Single submitter ⚠
- p.Pro113Leu Single submitter ⚠
- p.Pro129Leu Single submitter ⚠
- p.Pro150Leu Single submitter ⚠
- p.Pro151Ser Single submitter ⚠
- p.Pro37Thr Single submitter ⚠
- p.Pro39Ser Single submitter ⚠
- p.Pro65Ser Single submitter ⚠
- p.Pro88Ser Single submitter ⚠
- p.Ser125Gly Single submitter ⚠
- p.Ser59Asn Single submitter ⚠
- p.Ser84Gly Single submitter ⚠
- p.Thr136Ala Single submitter ⚠
- p.Val138Gly Single submitter ⚠