ARHGAP33 — 185 ClinVar variants

All ClinVar germline ARHGAP33 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

4 Benign · 11 Likely benign · 170 Uncertain significance

Full ARHGAP33 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All ARHGAP33 variants

Benign 4

p.Leu422= Multiple submitters
p.Thr544= Multiple submitters
p.Asp116= Single submitter
p.Leu502= Single submitter

Likely benign 11

c.1086-5C>G Single submitter
c.770-7C>T Single submitter
c.829+5T>C Single submitter
p.Ala23Thr Single submitter
p.Ala851Thr Single submitter
p.Arg1217His Single submitter
p.Asn954His Single submitter
p.Leu1052= Single submitter
p.Pro261= Single submitter
p.Pro828= Single submitter
p.Pro847Gln Single submitter

Uncertain significance 170

p.Ala1159Val Single submitter
p.Ala1212Val Single submitter
p.Ala461Thr Single submitter
p.Ala486Val Single submitter
p.Ala617Gly Single submitter
p.Ala647Thr Single submitter
p.Arg104His Single submitter
p.Arg1102His Single submitter
p.Arg1108Cys Single submitter
p.Arg1108His Single submitter
p.Arg112Gln Single submitter
p.Arg1161Cys Single submitter
p.Arg1161His Single submitter
p.Arg1196His Single submitter
p.Arg1205Cys Single submitter
p.Arg1205His Single submitter
p.Arg1211Gln Single submitter
p.Arg1217Pro Single submitter
p.Arg1236Gly Single submitter
p.Arg1244Ser Single submitter
p.Arg1250Gln Single submitter
p.Arg1284Gly Single submitter
p.Arg174Gln Single submitter
p.Arg196Gln Single submitter
p.Arg231Gln Single submitter
p.Arg280Gln Single submitter
p.Arg282His Single submitter
p.Arg290His Single submitter
p.Arg299Gln Single submitter
p.Arg299Trp Single submitter
p.Arg301Gln Single submitter
p.Arg301Trp Single submitter
p.Arg305Gln Single submitter
p.Arg362Trp Single submitter
p.Arg421His Single submitter
p.Arg424Gln Single submitter
p.Arg424Trp Single submitter
p.Arg462Cys Single submitter
p.Arg462His Single submitter
p.Arg493Gln Single submitter
p.Arg551Cys Single submitter
p.Arg555Gln Single submitter
p.Arg555Leu Single submitter
p.Arg584Gln Single submitter
p.Arg616His Single submitter
p.Arg70His Single submitter
p.Arg830Trp Single submitter
p.Arg861Trp Single submitter
p.Arg884Leu Single submitter
p.Arg92Cys Single submitter
p.Arg92His Single submitter
p.Arg994Gly Single submitter
p.Asn456Ser Single submitter
p.Asn471Ser Single submitter
p.Asp1133Asn Single submitter
p.Asp259Asn Single submitter
p.Asp427Asn Single submitter
p.Asp520Asn Single submitter
p.Cys242Arg Single submitter
p.Gln1002Leu Single submitter
p.Gln1026Arg Single submitter
p.Gln1061Glu Single submitter
p.Gln1208Lys Single submitter
p.Gln1259His Single submitter
p.Gln330His Single submitter
p.Gln918Leu Single submitter
p.Gln928Pro Single submitter
p.Gln974Arg Single submitter
p.Glu1039Gln Single submitter
p.Glu1083Asp Single submitter
p.Glu1083Gly Single submitter
p.Glu130Lys Single submitter
p.Glu319Lys Single submitter
p.Glu337Lys Single submitter
p.Glu364Gln Single submitter
p.Glu420Lys Single submitter
p.Glu845Lys Single submitter
p.Glu906Lys Single submitter
p.Gly1009Ser Single submitter
p.Gly1046Arg Single submitter
p.Gly1074Asp Single submitter
p.Gly1090Arg Single submitter
p.Gly1120Asp Single submitter
p.Gly1120Ser Single submitter
p.Gly1200Ser Single submitter
p.Gly1245Arg Single submitter
p.Gly253Ala Single submitter
p.Gly253Val Single submitter
p.Gly287Asp Single submitter
p.Gly41Asp Single submitter
p.Gly557Glu Single submitter
p.Gly580Arg Single submitter
p.Gly588Val Single submitter
p.Gly613Glu Single submitter
p.Gly72Arg Single submitter
p.Gly829Cys Single submitter
p.Gly886Arg Single submitter
p.Gly941Arg Single submitter
p.Gly945Arg Single submitter
p.Gly977Arg Single submitter
p.His1220Pro Single submitter
p.His1249Arg Single submitter
p.His505Arg Single submitter
p.His61Tyr Single submitter
p.Ile114Leu Single submitter
p.Ile212Thr Single submitter
p.Ile265Ser Single submitter
p.Ile382Val Single submitter
p.Leu1079Pro Single submitter
p.Leu1122Val Single submitter
p.Leu1253Phe Single submitter
p.Leu447Pro Single submitter
p.Leu810Gln Single submitter
p.Leu867Phe Single submitter
p.Leu935Arg Single submitter
p.Lys606Arg Single submitter
p.Phe1107Ser Single submitter
p.Phe292Leu Single submitter
p.Phe594Leu Single submitter
p.Pro1042Leu Single submitter
p.Pro1054Leu Single submitter
p.Pro1067Leu Single submitter
p.Pro1100Arg Single submitter
p.Pro1100Leu Single submitter
p.Pro1112Leu Single submitter
p.Pro1126Leu Single submitter
p.Pro1139Leu Single submitter
p.Pro1142Leu Single submitter
p.Pro1158Leu Single submitter
p.Pro1207Thr Single submitter
p.Pro1223Leu Single submitter
p.Pro1266Leu Single submitter
p.Pro1268Ser Single submitter
p.Pro1271Arg Single submitter
p.Pro19Thr Single submitter
p.Pro252Gln Single submitter
p.Pro262Arg Single submitter
p.Pro266Leu Single submitter
p.Pro329Ser Single submitter
p.Pro32Ala Single submitter
p.Pro521Thr Single submitter
p.Pro73Ser Single submitter
p.Pro847Leu Single submitter
p.Pro889Ser Single submitter
p.Pro891Leu Single submitter
p.Pro952Ser Single submitter
p.Pro959Arg Single submitter
p.Pro959Leu Single submitter
p.Pro959Ser Single submitter
p.Pro966Arg Single submitter
p.Pro966Thr Single submitter
p.Pro971Leu Single submitter
p.Ser1025Leu Single submitter
p.Ser1095Tyr Single submitter
p.Ser1180Pro Single submitter
p.Ser155Gly Single submitter
p.Ser16Thr Single submitter
p.Ser387Thr Single submitter
p.Ser602Cys Single submitter
p.Ser858Cys Single submitter
p.Ser936Pro Single submitter
p.Thr22Ser Single submitter
p.Thr291Asn Single submitter
p.Thr593Met Single submitter
p.Thr628Ile Single submitter
p.Trp468Gly Single submitter
p.Tyr1097Ser Single submitter
p.Val85Leu Single submitter
p.Val939Met Single submitter
p.Val999Ile Single submitter