ARHGEF33 — 125 ClinVar variants

All ClinVar germline ARHGEF33 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

3 Likely benign · 122 Uncertain significance

Full ARHGEF33 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All ARHGEF33 variants

Likely benign 3

p.Ile738Leu Single submitter
p.Ser129Gly Single submitter
p.Thr490Ser Single submitter

Uncertain significance 122

p.Ala165Thr Single submitter
p.Ala264Asp Single submitter
p.Ala326Val Single submitter
p.Ala468Pro Single submitter
p.Ala482Gly Single submitter
p.Ala567Val Single submitter
p.Ala597Val Single submitter
p.Ala624Ser Single submitter
p.Ala624Thr Single submitter
p.Ala680Gly Single submitter
p.Ala680Val Single submitter
p.Ala695Val Single submitter
p.Ala696Val Single submitter
p.Ala722Val Single submitter
p.Ala751Ser Single submitter
p.Ala759Thr Single submitter
p.Ala92Asp Single submitter
p.Arg306Lys Single submitter
p.Arg398Cys Single submitter
p.Arg452Gln Single submitter
p.Arg452Trp Single submitter
p.Arg488Cys Single submitter
p.Arg544Lys Single submitter
p.Arg593Pro Single submitter
p.Arg707His Single submitter
p.Arg724Ser Single submitter
p.Arg810Thr Single submitter
p.Arg818His Single submitter
p.Asn146Ser Single submitter
p.Asn159Ser Single submitter
p.Asn18Lys Single submitter
p.Asn200Tyr Single submitter
p.Asn590Ser Single submitter
p.Asn85Ser Single submitter
p.Asn862Asp Single submitter
p.Asp240His Single submitter
p.Asp564Gly Single submitter
p.Asp604Gly Single submitter
p.Gln164Arg Single submitter
p.Gln164His Single submitter
p.Gln318Arg Single submitter
p.Gln766His Single submitter
p.Glu149Lys Single submitter
p.Glu231Ala Single submitter
p.Glu259Lys Single submitter
p.Glu305Asp Single submitter
p.Glu414Asp Single submitter
p.Glu529Asp Single submitter
p.Glu55Lys Single submitter
p.Glu581Gln Single submitter
p.Glu614Asp Single submitter
p.Glu71Gln Single submitter
p.Gly230Ala Single submitter
p.Gly534Arg Single submitter
p.Gly543Asp Single submitter
p.Gly733Ser Single submitter
p.His405Tyr Single submitter
p.His49Gln Single submitter
p.Ile23Phe Single submitter
p.Ile282Val Single submitter
p.Ile284Phe Single submitter
p.Ile654Met Single submitter
p.Leu242Val Single submitter
p.Leu377Pro Single submitter
p.Leu430Phe Single submitter
p.Leu541Val Single submitter
p.Leu601Pro Single submitter
p.Leu639Val Single submitter
p.Leu709Ile Single submitter
p.Leu858Val Single submitter
p.Lys411Arg Single submitter
p.Lys535Asn Single submitter
p.Lys678Asn Single submitter
p.Lys701Thr Single submitter
p.Lys703Thr Single submitter
p.Lys739Thr Single submitter
p.Lys80Gln Single submitter
p.Met185Lys Single submitter
p.Met528Thr Single submitter
p.Phe309Leu Single submitter
p.Pro195Ser Single submitter
p.Pro480Arg Single submitter
p.Pro576Ser Single submitter
p.Pro645Leu Single submitter
p.Pro669Ser Single submitter
p.Pro675Ala Single submitter
p.Pro723Ala Single submitter
p.Pro765Ser Single submitter
p.Pro846Arg Single submitter
p.Ser129Arg Single submitter
p.Ser140Arg Single submitter
p.Ser163Phe Single submitter
p.Ser180Gly Single submitter
p.Ser206Leu Single submitter
p.Ser211Phe Single submitter
p.Ser479Phe Single submitter
p.Ser760Phe Single submitter
p.Ser805Thr Single submitter
p.Ser847Thr Single submitter
p.Thr123Ile Single submitter
p.Thr193Ala Single submitter
p.Thr21Pro Single submitter
p.Thr390Lys Single submitter
p.Thr438Ile Single submitter
p.Thr4Asn Single submitter
p.Thr4Ser Single submitter
p.Thr6Arg Single submitter
p.Thr728Ala Single submitter
p.Trp334Ser Single submitter
p.Trp539Cys Single submitter
p.Tyr280Cys Single submitter
p.Tyr357His Single submitter
p.Tyr629His Single submitter
p.Tyr834Ser Single submitter
p.Val118Ala Single submitter
p.Val256Ile Single submitter
p.Val281Ile Single submitter
p.Val331Ile Single submitter
p.Val427Ile Single submitter
p.Val518Leu Single submitter
p.Val609Met Single submitter
p.Val721Met Single submitter