ARPIN-AP3S2 — 1 ClinVar variant
All ClinVar germline ARPIN-AP3S2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 1 flagged for review →
1 Uncertain significance
Full ARPIN-AP3S2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 1
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All ARPIN-AP3S2 variants
Uncertain significance 1
- p.Pro388Ser Single submitter ⚠