ASB13 — 48 ClinVar variants
All ClinVar germline ASB13 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 48 flagged for review →
48 Uncertain significance
Full ASB13 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 48
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 23
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ASB13 p.Ala124Val Uncertain significance Single submitter
- ASB13 p.Ala189Thr Uncertain significance Single submitter
- ASB13 p.Ala210Asp Uncertain significance Single submitter
- ASB13 p.Ala210Pro Uncertain significance Single submitter
- ASB13 p.Ala263Thr Uncertain significance Single submitter
- ASB13 p.Ala58Thr Uncertain significance Single submitter
- ASB13 p.Arg251Met Uncertain significance Single submitter
- ASB13 p.Arg4Gln Uncertain significance Single submitter
- ASB13 p.Arg81Gly Uncertain significance Single submitter
- ASB13 p.Cys132Arg Uncertain significance Single submitter
- ASB13 p.Gln77Arg Uncertain significance Single submitter
- ASB13 p.Glu123Lys Uncertain significance Single submitter
- ASB13 p.Glu199Lys Uncertain significance Single submitter
- ASB13 p.Gly140Arg Uncertain significance Single submitter
- ASB13 p.Gly63Asp Uncertain significance Single submitter
- ASB13 p.Gly8Cys Uncertain significance Single submitter
- ASB13 p.Met126Leu Uncertain significance Single submitter
- ASB13 p.Pro113Arg Uncertain significance Single submitter
- ASB13 p.Pro269Leu Uncertain significance Single submitter
- ASB13 p.Pro88Leu Uncertain significance Single submitter
- ASB13 p.Ser32Cys Uncertain significance Single submitter
- ASB13 p.Val18Leu Uncertain significance Single submitter
- ASB13 p.Val23Met Uncertain significance Single submitter
Predictors split 25
The independent predictors disagree with each other — read with care.
- ASB13 p.Ala190Ser Uncertain significance Single submitter
- ASB13 p.Arg160Gln Uncertain significance Single submitter
- ASB13 p.Arg211Gln Uncertain significance Single submitter
- ASB13 p.Arg211Trp Uncertain significance Single submitter
- ASB13 p.Arg214Cys Uncertain significance Single submitter
- ASB13 p.Arg270Trp Uncertain significance Single submitter
- ASB13 p.Arg29Gln Uncertain significance Single submitter
- ASB13 p.Asn175Lys Uncertain significance Single submitter
- ASB13 p.Asp13Tyr Uncertain significance Single submitter
- ASB13 p.Cys231Ser Uncertain significance Single submitter
- ASB13 p.Gln47Arg Uncertain significance Single submitter
- ASB13 p.Glu183Lys Uncertain significance Single submitter
- ASB13 p.Glu31Gly Uncertain significance Single submitter
- ASB13 p.Glu99Lys Uncertain significance Single submitter
- ASB13 p.Gly206Cys Uncertain significance Single submitter
- ASB13 p.Ile262Val Uncertain significance Single submitter
- ASB13 p.Leu271Phe Uncertain significance Single submitter
- ASB13 p.Ser224Cys Uncertain significance Single submitter
- ASB13 p.Ser86Asn Uncertain significance Single submitter
- ASB13 p.Ser97Arg Uncertain significance Single submitter
- ASB13 p.Ser97Ile Uncertain significance Single submitter
- ASB13 p.Thr238Ile Uncertain significance Single submitter
- ASB13 p.Val139Ile Uncertain significance Single submitter
- ASB13 p.Val168Met Uncertain significance Single submitter
- ASB13 p.Val50Leu Uncertain significance Single submitter
All ASB13 variants
Uncertain significance 48
- p.Ala124Val Single submitter ⚠
- p.Ala189Thr Single submitter ⚠
- p.Ala190Ser Single submitter ⚠
- p.Ala210Asp Single submitter ⚠
- p.Ala210Pro Single submitter ⚠
- p.Ala263Thr Single submitter ⚠
- p.Ala58Thr Single submitter ⚠
- p.Arg160Gln Single submitter ⚠
- p.Arg211Gln Single submitter ⚠
- p.Arg211Trp Single submitter ⚠
- p.Arg214Cys Single submitter ⚠
- p.Arg251Met Single submitter ⚠
- p.Arg270Trp Single submitter ⚠
- p.Arg29Gln Single submitter ⚠
- p.Arg4Gln Single submitter ⚠
- p.Arg81Gly Single submitter ⚠
- p.Asn175Lys Single submitter ⚠
- p.Asp13Tyr Single submitter ⚠
- p.Cys132Arg Single submitter ⚠
- p.Cys231Ser Single submitter ⚠
- p.Gln47Arg Single submitter ⚠
- p.Gln77Arg Single submitter ⚠
- p.Glu123Lys Single submitter ⚠
- p.Glu183Lys Single submitter ⚠
- p.Glu199Lys Single submitter ⚠
- p.Glu31Gly Single submitter ⚠
- p.Glu99Lys Single submitter ⚠
- p.Gly140Arg Single submitter ⚠
- p.Gly206Cys Single submitter ⚠
- p.Gly63Asp Single submitter ⚠
- p.Gly8Cys Single submitter ⚠
- p.Ile262Val Single submitter ⚠
- p.Leu271Phe Single submitter ⚠
- p.Met126Leu Single submitter ⚠
- p.Pro113Arg Single submitter ⚠
- p.Pro269Leu Single submitter ⚠
- p.Pro88Leu Single submitter ⚠
- p.Ser224Cys Single submitter ⚠
- p.Ser32Cys Single submitter ⚠
- p.Ser86Asn Single submitter ⚠
- p.Ser97Arg Single submitter ⚠
- p.Ser97Ile Single submitter ⚠
- p.Thr238Ile Single submitter ⚠
- p.Val139Ile Single submitter ⚠
- p.Val168Met Single submitter ⚠
- p.Val18Leu Single submitter ⚠
- p.Val23Met Single submitter ⚠
- p.Val50Leu Single submitter ⚠