ATG13 — 66 ClinVar variants
All ClinVar germline ATG13 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 59 flagged for review →
2 Benign · 64 Uncertain significance
Full ATG13 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 59
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 45
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ATG13 p.Ala317Thr Uncertain significance Single submitter
- ATG13 p.Ala374Asp Uncertain significance Single submitter
- ATG13 p.Ala393Thr Uncertain significance Single submitter
- ATG13 p.Ala518Thr Uncertain significance Single submitter
- ATG13 p.Arg218Cys Uncertain significance Single submitter
- ATG13 p.Arg218His Uncertain significance Single submitter
- ATG13 p.Arg540His Uncertain significance Single submitter
- ATG13 p.Asn230Ser Uncertain significance Single submitter
- ATG13 p.Asn327Ser Uncertain significance Single submitter
- ATG13 p.Asn434Asp Uncertain significance Single submitter
- ATG13 p.Asp439Val Uncertain significance Single submitter
- ATG13 p.Asp441Asn Uncertain significance Single submitter
- ATG13 p.Cys100Phe Uncertain significance Single submitter
- ATG13 p.Cys38Gly Uncertain significance Single submitter
- ATG13 p.Gln550Arg Uncertain significance Single submitter
- ATG13 p.Glu83Lys Uncertain significance Single submitter
- ATG13 p.Gly391Ala Uncertain significance Single submitter
- ATG13 p.Gly458Ser Uncertain significance Single submitter
- ATG13 p.His474Arg Uncertain significance Single submitter
- ATG13 p.Ile241Met Uncertain significance Single submitter
- ATG13 p.Ile98Thr Uncertain significance Single submitter
- ATG13 p.Leu302Arg Uncertain significance Single submitter
- ATG13 p.Leu460Gln Uncertain significance Single submitter
- ATG13 p.Lys433Asn Uncertain significance Single submitter
- ATG13 p.Lys56Arg Uncertain significance Single submitter
- ATG13 p.Met429Leu Uncertain significance Single submitter
- ATG13 p.Pro225Leu Uncertain significance Single submitter
- ATG13 p.Pro243Leu Uncertain significance Single submitter
- ATG13 p.Pro376Leu Uncertain significance Single submitter
- ATG13 p.Pro395Leu Uncertain significance Single submitter
- ATG13 p.Ser162Arg Uncertain significance Single submitter
- ATG13 p.Ser300Ala Uncertain significance Single submitter
- ATG13 p.Ser389Asn Uncertain significance Single submitter
- ATG13 p.Ser465Phe Uncertain significance Single submitter
- ATG13 p.Thr116Met Uncertain significance Single submitter
- ATG13 p.Thr175Ile Uncertain significance Single submitter
- ATG13 p.Thr184Ser Uncertain significance Single submitter
- ATG13 p.Thr198Ala Uncertain significance Single submitter
- ATG13 p.Thr365Ser Uncertain significance Single submitter
- ATG13 p.Thr421Met Uncertain significance Single submitter
- ATG13 p.Thr473Ser Uncertain significance Single submitter
- ATG13 p.Val311Ile Uncertain significance Single submitter
- ATG13 p.Val311Phe Uncertain significance Single submitter
- ATG13 p.Val336Ile Uncertain significance Single submitter
- ATG13 p.Val385Ile Uncertain significance Single submitter
Predictors split 14
The independent predictors disagree with each other — read with care.
- ATG13 p.Arg40Cys Uncertain significance Single submitter
- ATG13 p.Asn412Lys Uncertain significance Single submitter
- ATG13 p.Asp14Gly Uncertain significance Single submitter
- ATG13 p.Cys81Ser Uncertain significance Single submitter
- ATG13 p.Ile212Thr Uncertain significance Single submitter
- ATG13 p.Leu22Val Uncertain significance Single submitter
- ATG13 p.Leu492Phe Uncertain significance Single submitter
- ATG13 p.Phe256Leu Uncertain significance Single submitter
- ATG13 p.Pro206Arg Uncertain significance Single submitter
- ATG13 p.Pro493Leu Uncertain significance Single submitter
- ATG13 p.Ser257Pro Uncertain significance Single submitter
- ATG13 p.Ser44Phe Uncertain significance Single submitter
- ATG13 p.Thr548Ile Uncertain significance Single submitter
- ATG13 p.Tyr500Cys Uncertain significance Single submitter
All ATG13 variants
Uncertain significance 64
- p.Ala289Thr Single submitter
- p.Ala317Thr Single submitter ⚠
- p.Ala374Asp Single submitter ⚠
- p.Ala393Thr Single submitter ⚠
- p.Ala518Thr Single submitter ⚠
- p.Ala544Asp Single submitter
- p.Arg218Cys Single submitter ⚠
- p.Arg218His Single submitter ⚠
- p.Arg40Cys Single submitter ⚠
- p.Arg501Gln Single submitter
- p.Arg540His Single submitter ⚠
- p.Asn230Ser Single submitter ⚠
- p.Asn327Ser Single submitter ⚠
- p.Asn412Lys Single submitter ⚠
- p.Asn434Asp Single submitter ⚠
- p.Asp14Gly Single submitter ⚠
- p.Asp439Val Single submitter ⚠
- p.Asp441Asn Single submitter ⚠
- p.Cys100Phe Single submitter ⚠
- p.Cys38Gly Single submitter ⚠
- p.Cys81Ser Single submitter ⚠
- p.Gln550Arg Single submitter ⚠
- p.Glu83Lys Single submitter ⚠
- p.Gly391Ala Single submitter ⚠
- p.Gly458Ser Single submitter ⚠
- p.His474Arg Single submitter ⚠
- p.Ile212Thr Single submitter ⚠
- p.Ile241Met Single submitter ⚠
- p.Ile98Thr Single submitter ⚠
- p.Leu22Val Single submitter ⚠
- p.Leu302Arg Single submitter ⚠
- p.Leu460Gln Single submitter ⚠
- p.Leu492Phe Single submitter ⚠
- p.Lys433Asn Single submitter ⚠
- p.Lys56Arg Single submitter ⚠
- p.Met429Leu Single submitter ⚠
- p.Phe256Leu Single submitter ⚠
- p.Pro206Arg Single submitter ⚠
- p.Pro225Leu Single submitter ⚠
- p.Pro243Leu Single submitter ⚠
- p.Pro376Leu Single submitter ⚠
- p.Pro395Leu Single submitter ⚠
- p.Pro493Leu Single submitter ⚠
- p.Ser162Arg Single submitter ⚠
- p.Ser257Pro Single submitter ⚠
- p.Ser300Ala Single submitter ⚠
- p.Ser389Asn Single submitter ⚠
- p.Ser44Phe Single submitter ⚠
- p.Ser465Phe Single submitter ⚠
- p.Thr116Met Single submitter ⚠
- p.Thr175Ile Single submitter ⚠
- p.Thr184Ser Single submitter ⚠
- p.Thr198Ala Single submitter ⚠
- p.Thr283Asn Single submitter
- p.Thr365Ser Single submitter ⚠
- p.Thr421Met Single submitter ⚠
- p.Thr473Ser Single submitter ⚠
- p.Thr548Ile Single submitter ⚠
- p.Tyr500Cys Single submitter ⚠
- p.Val311Ile Single submitter ⚠
- p.Val311Phe Single submitter ⚠
- p.Val336Ile Single submitter ⚠
- p.Val385Ile Single submitter ⚠
- c.1576-1G>C No assertion criteria prostate cancer