ATM — 17666 ClinVar variants

Predictors split 331

The independent predictors disagree with each other — read with care. · showing the 150 best-reviewed of 331

• ATM p.Ala108Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ala108Thr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ala108Val Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ala1732Gly Uncertain significance Multiple submitters

  familial colorectal cancer type X

• ATM p.Ala188Asp Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ala2296Thr Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ala2851Val Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ala416Pro Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg13Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg221Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg2263Lys Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Arg2459Gly Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Arg2459His Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg2547Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg2547Ile Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg2691Cys Uncertain significance Multiple submitters

  familial colorectal cancer type X

• ATM p.Arg2854His Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg337Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Arg90Ser Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asn109Asp Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asn1549Lys Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asn2267Ile Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asn246Lys Uncertain significance Multiple submitters

  ATM-related disorder

• ATM p.Asn883Lys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp1563Asn Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp1682Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp1682Tyr Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asp1682Val Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asp1935Tyr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp2110His Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asp2320Tyr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp2551Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp2551His Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Asp2625Ala Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp2672Ala Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp817Val Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Asp965His Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Cys2349Tyr Uncertain significance Multiple submitters

  ATM-related cancer predisposition

• ATM p.Cys2464Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln1919Lys Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Gln2177Arg Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln2177Glu Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Gln2399Glu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln2399Lys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln2433His Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln2433Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln2729Glu Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Gln2762Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Gln654Pro Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gln65His Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Glu2157Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Glu2362Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Glu2449Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Glu2668Lys Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Glu26Asp Uncertain significance Multiple submitters

  hereditary breast carcinoma

• ATM p.Glu2744Ala Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Glu2880Val Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Glu3007Asp Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Glu609Lys Uncertain significance Multiple submitters

  hereditary breast ovarian cancer syndrome

• ATM p.Gly228Asp Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Gly2709Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gly2772Ala Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Gly294Arg Uncertain significance Multiple submitters

  hereditary breast carcinoma

• ATM p.His1951Pro Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.His2038Gln Uncertain significance Multiple submitters

  familial colorectal cancer type X

• ATM p.His2538Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.His2554Tyr Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.His46Pro Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ile1271Thr Uncertain significance Multiple submitters

  hereditary breast carcinoma

• ATM p.Ile2179Thr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ile2401Thr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ile2471Phe Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ile2702Met Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ile2752Met Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ile3036Leu Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ile3036Val Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu1561Pro Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2098Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2163Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2163His Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2211Arg Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu2234Gln Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu2293Gln Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2338Val Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2452Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2452Gln Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu2455Gln Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu2519Val Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Leu2760Val Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu2945Val Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu3048Val Uncertain significance Multiple submitters

  hereditary breast carcinoma

• ATM p.Leu427Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Leu686His Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys106Asn Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys1738Arg Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys2363Glu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys2363Met Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys2421Ile Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys2421Thr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys2465Gln Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys24Glu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys24Met Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys2530Glu Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Lys31Asn Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys331Asn Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Lys573Asn Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Lys70Asn Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Lys93Glu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Met2616Thr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Met2667Thr Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Met2935Val Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Met349Ile Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Met753Thr Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe1077Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe1265Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe1336Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe1491Leu Uncertain significance Multiple submitters

  familial colorectal cancer type X

• ATM p.Phe1683Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe2219Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe505Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe523Leu Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Phe652Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Phe652Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Pro2512Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Pro2512Thr Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Pro2518Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Pro2793Ser Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser1684Cys Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ser1990Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ser1993Ile Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser2168Trp Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser2592Cys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser2592Pro Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser2859Cys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser2882Leu Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ser3027Gly Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Ser3046Gly Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Ser98Arg Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Thr1609Ile Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Thr1926Lys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Thr1953Ala Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Thr1997Pro Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Thr2682Pro Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Thr2921Met Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Thr2961Ala Uncertain significance Multiple submitters

  ataxia telangiectasia

• ATM p.Trp1026Cys Pathogenic/Likely pathogenic Multiple submitters

  ataxia telangiectasia

• ATM p.Trp1750Leu Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Tyr1252Cys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Tyr1319Cys Uncertain significance Multiple submitters

  hereditary neoplastic syndrome

• ATM p.Tyr1392Cys Uncertain significance Multiple submitters

  ataxia telangiectasia