ATP5MG — 18 ClinVar variants
All ClinVar germline ATP5MG variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 17 flagged for review →
1 Likely benign · 17 Uncertain significance
Full ATP5MG gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 17
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 12
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ATP5MG p.Ala34Thr Uncertain significance Single submitter
- ATP5MG p.Arg26Leu Uncertain significance Single submitter
- ATP5MG p.Arg96Pro Uncertain significance Single submitter
- ATP5MG p.Arg96Trp Uncertain significance Single submitter
- ATP5MG p.Asn58Ser Uncertain significance Single submitter
- ATP5MG p.Glu10Ala Uncertain significance Single submitter
- ATP5MG p.Leu27Ser Uncertain significance Single submitter
- ATP5MG p.Lys35Arg Uncertain significance Single submitter
- ATP5MG p.Pro43His Uncertain significance Single submitter
- ATP5MG p.Ser23Trp Uncertain significance Single submitter
- ATP5MG p.Thr62Ser Uncertain significance Single submitter
- ATP5MG p.Val79Met Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All ATP5MG variants
Likely benign 1
- p.Arg48Thr Single submitter
Uncertain significance 17
- p.Ala34Thr Single submitter ⚠
- p.Arg26Leu Single submitter ⚠
- p.Arg96Pro Single submitter ⚠
- p.Arg96Trp Single submitter ⚠
- p.Asn58Ser Single submitter ⚠
- p.Asn7Ile Single submitter ⚠
- p.Glu10Ala Single submitter ⚠
- p.Ile50Thr Single submitter ⚠
- p.Leu27Met Single submitter ⚠
- p.Leu27Ser Single submitter ⚠
- p.Lys35Arg Single submitter ⚠
- p.Pro13Leu Single submitter ⚠
- p.Pro43His Single submitter ⚠
- p.Ser23Trp Single submitter ⚠
- p.Thr12Asn Single submitter ⚠
- p.Thr62Ser Single submitter ⚠
- p.Val79Met Single submitter ⚠