ATRAID — 44 ClinVar variants
All ClinVar germline ATRAID variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 31 flagged for review →
4 Likely benign · 40 Uncertain significance
Full ATRAID gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 31
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 22
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ATRAID p.Ala16Val Uncertain significance Single submitter
- ATRAID p.Ala2Pro Uncertain significance Single submitter
- ATRAID p.Arg27Gly Uncertain significance Single submitter
- ATRAID p.Asn157Asp Uncertain significance Single submitter
- ATRAID p.Asn67Ser Uncertain significance Single submitter
- ATRAID p.Asn88Thr Uncertain significance Single submitter
- ATRAID p.Asp145Tyr Uncertain significance Single submitter
- ATRAID p.Asp5Tyr Uncertain significance Single submitter
- ATRAID p.Cys171Arg Uncertain significance Single submitter
- ATRAID p.Cys171Ser Uncertain significance Single submitter
- ATRAID p.Cys35Tyr Uncertain significance Single submitter
- ATRAID p.Glu33Lys Uncertain significance Single submitter
- ATRAID p.Glu57Asp Uncertain significance Single submitter
- ATRAID p.Gly175Ala Uncertain significance Single submitter
- ATRAID p.Ile216Phe Uncertain significance Single submitter
- ATRAID p.Leu12Val Uncertain significance Single submitter
- ATRAID p.Lys227Glu Uncertain significance Single submitter
- ATRAID p.Thr159Ser Uncertain significance Single submitter
- ATRAID p.Thr210Ser Uncertain significance Single submitter
- ATRAID p.Tyr143Asn Uncertain significance Single submitter
- ATRAID p.Val128Leu Uncertain significance Single submitter
- ATRAID p.Val42Ala Uncertain significance Single submitter
Predictors split 9
The independent predictors disagree with each other — read with care.
- ATRAID p.Ala49Pro Uncertain significance Single submitter
- ATRAID p.Arg114Cys Uncertain significance Single submitter
- ATRAID p.Arg223Gly Uncertain significance Single submitter
- ATRAID p.Gly107Ser Uncertain significance Single submitter
- ATRAID p.Gly133Glu Uncertain significance Single submitter
- ATRAID p.His188Leu Uncertain significance Single submitter
- ATRAID p.Leu12Pro Uncertain significance Single submitter
- ATRAID p.Leu9Phe Uncertain significance Single submitter
- ATRAID p.Ser142Cys Uncertain significance Single submitter
All ATRAID variants
Likely benign 4
- c.-45G>A Single submitter
- p.Arg114His Single submitter
- p.Ile123Val Single submitter
- p.Lys153Arg Single submitter
Uncertain significance 40
- c.-117C>A Single submitter
- c.-123A>C Single submitter
- c.-155G>A Single submitter
- c.-161A>G Single submitter
- c.-24A>T Single submitter
- c.-38C>T Single submitter
- c.-44C>G Single submitter
- c.-71G>A Single submitter
- c.-74G>C Single submitter
- p.Ala16Val Single submitter ⚠
- p.Ala2Pro Single submitter ⚠
- p.Ala49Pro Single submitter ⚠
- p.Arg114Cys Single submitter ⚠
- p.Arg223Gly Single submitter ⚠
- p.Arg27Gly Single submitter ⚠
- p.Asn157Asp Single submitter ⚠
- p.Asn67Ser Single submitter ⚠
- p.Asn88Thr Single submitter ⚠
- p.Asp145Tyr Single submitter ⚠
- p.Asp5Tyr Single submitter ⚠
- p.Cys171Arg Single submitter ⚠
- p.Cys171Ser Single submitter ⚠
- p.Cys35Tyr Single submitter ⚠
- p.Glu33Lys Single submitter ⚠
- p.Glu57Asp Single submitter ⚠
- p.Gly107Ser Single submitter ⚠
- p.Gly133Glu Single submitter ⚠
- p.Gly175Ala Single submitter ⚠
- p.His188Leu Single submitter ⚠
- p.Ile216Phe Single submitter ⚠
- p.Leu12Pro Single submitter ⚠
- p.Leu12Val Single submitter ⚠
- p.Leu9Phe Single submitter ⚠
- p.Lys227Glu Single submitter ⚠
- p.Ser142Cys Single submitter ⚠
- p.Thr159Ser Single submitter ⚠
- p.Thr210Ser Single submitter ⚠
- p.Tyr143Asn Single submitter ⚠
- p.Val128Leu Single submitter ⚠
- p.Val42Ala Single submitter ⚠