B3GNT9 — 65 ClinVar variants
All ClinVar germline B3GNT9 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 64 flagged for review →
1 Likely benign · 64 Uncertain significance
Full B3GNT9 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 64
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 30
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- B3GNT9 p.Ala196Asp Uncertain significance Single submitter
- B3GNT9 p.Ala213Gly Uncertain significance Single submitter
- B3GNT9 p.Arg152Pro Uncertain significance Single submitter
- B3GNT9 p.Arg160Ser Uncertain significance Single submitter
- B3GNT9 p.Arg265His Uncertain significance Single submitter
- B3GNT9 p.Arg40Gly Uncertain significance Single submitter
- B3GNT9 p.Arg86Gly Uncertain significance Single submitter
- B3GNT9 p.Asp109Glu Uncertain significance Single submitter
- B3GNT9 p.Asp60Glu Uncertain significance Single submitter
- B3GNT9 p.Gln250Glu Uncertain significance Single submitter
- B3GNT9 p.Glu127Gln Uncertain significance Single submitter
- B3GNT9 p.Gly237Glu Uncertain significance Single submitter
- B3GNT9 p.Gly289Arg Uncertain significance Single submitter
- B3GNT9 p.Gly289Ser Uncertain significance Single submitter
- B3GNT9 p.Gly31Arg Uncertain significance Single submitter
- B3GNT9 p.Gly31Ser Uncertain significance Single submitter
- B3GNT9 p.Gly366Arg Uncertain significance Single submitter
- B3GNT9 p.Gly52Ala Uncertain significance Single submitter
- B3GNT9 p.His333Gln Uncertain significance Single submitter
- B3GNT9 p.Ile100Val Uncertain significance Single submitter
- B3GNT9 p.Leu240Pro Uncertain significance Single submitter
- B3GNT9 p.Leu323Pro Uncertain significance Single submitter
- B3GNT9 p.Leu7Pro Uncertain significance Single submitter
- B3GNT9 p.Phe56Leu Uncertain significance Single submitter
- B3GNT9 p.Phe96Ser Uncertain significance Single submitter
- B3GNT9 p.Pro284Ser Uncertain significance Single submitter
- B3GNT9 p.Pro39Ala Uncertain significance Single submitter
- B3GNT9 p.Pro81Leu Uncertain significance Single submitter
- B3GNT9 p.Tyr286His Uncertain significance Single submitter
- B3GNT9 p.Val158Met Uncertain significance Single submitter
Predictors split 34
The independent predictors disagree with each other — read with care.
- B3GNT9 p.Ala134Val Uncertain significance Single submitter
- B3GNT9 p.Ala180Val Uncertain significance Single submitter
- B3GNT9 p.Ala213Val Uncertain significance Single submitter
- B3GNT9 p.Ala217Pro Uncertain significance Single submitter
- B3GNT9 p.Ala287Gly Uncertain significance Single submitter
- B3GNT9 p.Ala305Gly Uncertain significance Single submitter
- B3GNT9 p.Ala305Thr Uncertain significance Single submitter
- B3GNT9 p.Ala307Val Uncertain significance Single submitter
- B3GNT9 p.Ala335Ser Uncertain significance Single submitter
- B3GNT9 p.Ala346Val Uncertain significance Single submitter
- B3GNT9 p.Ala38Thr Uncertain significance Single submitter
- B3GNT9 p.Arg183Trp Uncertain significance Single submitter
- B3GNT9 p.Arg262Trp Uncertain significance Single submitter
- B3GNT9 p.Arg267Trp Uncertain significance Single submitter
- B3GNT9 p.Arg6Cys Uncertain significance Single submitter
- B3GNT9 p.Arg8Cys Uncertain significance Single submitter
- B3GNT9 p.Asp247Glu Uncertain significance Single submitter
- B3GNT9 p.Asp371His Uncertain significance Single submitter
- B3GNT9 p.Gln324His Uncertain significance Single submitter
- B3GNT9 p.Gly143Ser Uncertain significance Single submitter
- B3GNT9 p.Gly147Arg Uncertain significance Single submitter
- B3GNT9 p.Gly296Val Uncertain significance Single submitter
- B3GNT9 p.Leu253Ile Uncertain significance Single submitter
- B3GNT9 p.Leu326Arg Uncertain significance Single submitter
- B3GNT9 p.Phe129Leu Uncertain significance Single submitter
- B3GNT9 p.Pro248Leu Uncertain significance Single submitter
- B3GNT9 p.Pro334Thr Uncertain significance Single submitter
- B3GNT9 p.Pro348Ser Uncertain significance Single submitter
- B3GNT9 p.Pro75Leu Uncertain significance Single submitter
- B3GNT9 p.Thr176Ile Uncertain significance Single submitter
- B3GNT9 p.Thr298Met Uncertain significance Single submitter
- B3GNT9 p.Thr79Met Uncertain significance Single submitter
- B3GNT9 p.Tyr26Cys Uncertain significance Single submitter
- B3GNT9 p.Val145Leu Uncertain significance Single submitter
All B3GNT9 variants
Likely benign 1
- p.Gln343Arg Single submitter
Uncertain significance 64
- p.Ala134Val Single submitter ⚠
- p.Ala180Val Single submitter ⚠
- p.Ala196Asp Single submitter ⚠
- p.Ala213Gly Single submitter ⚠
- p.Ala213Val Single submitter ⚠
- p.Ala217Pro Single submitter ⚠
- p.Ala287Gly Single submitter ⚠
- p.Ala305Gly Single submitter ⚠
- p.Ala305Thr Single submitter ⚠
- p.Ala307Val Single submitter ⚠
- p.Ala335Ser Single submitter ⚠
- p.Ala346Val Single submitter ⚠
- p.Ala38Thr Single submitter ⚠
- p.Arg152Pro Single submitter ⚠
- p.Arg160Ser Single submitter ⚠
- p.Arg183Trp Single submitter ⚠
- p.Arg262Trp Single submitter ⚠
- p.Arg265His Single submitter ⚠
- p.Arg267Trp Single submitter ⚠
- p.Arg40Gly Single submitter ⚠
- p.Arg6Cys Single submitter ⚠
- p.Arg86Gly Single submitter ⚠
- p.Arg8Cys Single submitter ⚠
- p.Asp109Glu Single submitter ⚠
- p.Asp247Glu Single submitter ⚠
- p.Asp371His Single submitter ⚠
- p.Asp60Glu Single submitter ⚠
- p.Gln250Glu Single submitter ⚠
- p.Gln324His Single submitter ⚠
- p.Glu127Gln Single submitter ⚠
- p.Gly143Ser Single submitter ⚠
- p.Gly147Arg Single submitter ⚠
- p.Gly237Glu Single submitter ⚠
- p.Gly289Arg Single submitter ⚠
- p.Gly289Ser Single submitter ⚠
- p.Gly296Val Single submitter ⚠
- p.Gly31Arg Single submitter ⚠
- p.Gly31Ser Single submitter ⚠
- p.Gly366Arg Single submitter ⚠
- p.Gly52Ala Single submitter ⚠
- p.His333Gln Single submitter ⚠
- p.Ile100Val Single submitter ⚠
- p.Leu240Pro Single submitter ⚠
- p.Leu253Ile Single submitter ⚠
- p.Leu323Pro Single submitter ⚠
- p.Leu326Arg Single submitter ⚠
- p.Leu7Pro Single submitter ⚠
- p.Phe129Leu Single submitter ⚠
- p.Phe56Leu Single submitter ⚠
- p.Phe96Ser Single submitter ⚠
- p.Pro248Leu Single submitter ⚠
- p.Pro284Ser Single submitter ⚠
- p.Pro334Thr Single submitter ⚠
- p.Pro348Ser Single submitter ⚠
- p.Pro39Ala Single submitter ⚠
- p.Pro75Leu Single submitter ⚠
- p.Pro81Leu Single submitter ⚠
- p.Thr176Ile Single submitter ⚠
- p.Thr298Met Single submitter ⚠
- p.Thr79Met Single submitter ⚠
- p.Tyr26Cys Single submitter ⚠
- p.Tyr286His Single submitter ⚠
- p.Val145Leu Single submitter ⚠
- p.Val158Met Single submitter ⚠