B4GALT6 — 37 ClinVar variants
All ClinVar germline B4GALT6 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 36 flagged for review →
1 Benign · 36 Uncertain significance
Full B4GALT6 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 36
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 23
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- B4GALT6 p.Arg186Gln Uncertain significance Single submitter
- B4GALT6 p.Arg186Trp Uncertain significance Single submitter
- B4GALT6 p.Arg334Trp Uncertain significance Single submitter
- B4GALT6 p.Arg356Lys Uncertain significance Single submitter
- B4GALT6 p.Arg49Gln Uncertain significance Single submitter
- B4GALT6 p.Arg9Gly Uncertain significance Single submitter
- B4GALT6 p.Asn12Ser Uncertain significance Single submitter
- B4GALT6 p.Asn83Ser Uncertain significance Single submitter
- B4GALT6 p.Asp140Asn Uncertain significance Single submitter
- B4GALT6 p.Glu81Lys Uncertain significance Single submitter
- B4GALT6 p.Gly145Val Uncertain significance Single submitter
- B4GALT6 p.Ile173Val Uncertain significance Single submitter
- B4GALT6 p.Ile19Phe Uncertain significance Single submitter
- B4GALT6 p.Ile368Val Uncertain significance Single submitter
- B4GALT6 p.Leu4Phe Uncertain significance Single submitter
- B4GALT6 p.Lys279Arg Uncertain significance Single submitter
- B4GALT6 p.Phe20Ile Uncertain significance Single submitter
- B4GALT6 p.Ser14Phe Uncertain significance Single submitter
- B4GALT6 p.Ser23Thr Uncertain significance Single submitter
- B4GALT6 p.Ser25Phe Uncertain significance Single submitter
- B4GALT6 p.Val158Ala Uncertain significance Single submitter
- B4GALT6 p.Val308Ile Uncertain significance Single submitter
- B4GALT6 p.Val57Met Uncertain significance Single submitter
Predictors split 13
The independent predictors disagree with each other — read with care.
- B4GALT6 p.Ala304Gly Uncertain significance Single submitter
- B4GALT6 p.Ala304Thr Uncertain significance Single submitter
- B4GALT6 p.Arg13Leu Uncertain significance Single submitter
- B4GALT6 p.Arg13Ser Uncertain significance Single submitter
- B4GALT6 p.Asn166Ser Uncertain significance Single submitter
- B4GALT6 p.Asp129Gly Uncertain significance Single submitter
- B4GALT6 p.Gln330Arg Uncertain significance Single submitter
- B4GALT6 p.Leu74Phe Uncertain significance Single submitter
- B4GALT6 p.Met216Thr Uncertain significance Single submitter
- B4GALT6 p.Pro113Ser Uncertain significance Single submitter
- B4GALT6 p.Pro36Ser Uncertain significance Single submitter
- B4GALT6 p.Ser124Gly Uncertain significance Single submitter
- B4GALT6 p.Tyr382Cys Uncertain significance Single submitter
All B4GALT6 variants
Benign 1
- p.Ile32Val Multiple submitters
Uncertain significance 36
- p.Ala304Gly Single submitter ⚠
- p.Ala304Thr Single submitter ⚠
- p.Arg13Leu Single submitter ⚠
- p.Arg13Ser Single submitter ⚠
- p.Arg186Gln Single submitter ⚠
- p.Arg186Trp Single submitter ⚠
- p.Arg334Trp Single submitter ⚠
- p.Arg356Lys Single submitter ⚠
- p.Arg49Gln Single submitter ⚠
- p.Arg9Gly Single submitter ⚠
- p.Asn12Ser Single submitter ⚠
- p.Asn166Ser Single submitter ⚠
- p.Asn83Ser Single submitter ⚠
- p.Asp129Gly Single submitter ⚠
- p.Asp140Asn Single submitter ⚠
- p.Gln330Arg Single submitter ⚠
- p.Glu81Lys Single submitter ⚠
- p.Gly145Val Single submitter ⚠
- p.Ile173Val Single submitter ⚠
- p.Ile19Phe Single submitter ⚠
- p.Ile368Val Single submitter ⚠
- p.Leu4Phe Single submitter ⚠
- p.Leu74Phe Single submitter ⚠
- p.Lys279Arg Single submitter ⚠
- p.Met216Thr Single submitter ⚠
- p.Phe20Ile Single submitter ⚠
- p.Pro113Ser Single submitter ⚠
- p.Pro36Ser Single submitter ⚠
- p.Ser124Gly Single submitter ⚠
- p.Ser14Phe Single submitter ⚠
- p.Ser23Thr Single submitter ⚠
- p.Ser25Phe Single submitter ⚠
- p.Tyr382Cys Single submitter ⚠
- p.Val158Ala Single submitter ⚠
- p.Val308Ile Single submitter ⚠
- p.Val57Met Single submitter ⚠