BAIAP2L2 — 119 ClinVar variants
All ClinVar germline BAIAP2L2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 113 flagged for review →
6 Likely benign · 113 Uncertain significance
Full BAIAP2L2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 113
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 59
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- BAIAP2L2 p.Ala163Val Uncertain significance Single submitter
- BAIAP2L2 p.Ala62Val Uncertain significance Single submitter
- BAIAP2L2 p.Arg160Gln Uncertain significance Single submitter
- BAIAP2L2 p.Arg228Ser Uncertain significance Single submitter
- BAIAP2L2 p.Arg296Pro Uncertain significance Single submitter
- BAIAP2L2 p.Arg475His Uncertain significance Single submitter
- BAIAP2L2 p.Arg476His Uncertain significance Single submitter
- BAIAP2L2 p.Arg523His Uncertain significance Single submitter
- BAIAP2L2 p.Arg61His Uncertain significance Single submitter
- BAIAP2L2 p.Asn196Asp Uncertain significance Single submitter
- BAIAP2L2 p.Asn24Lys Uncertain significance Single submitter
- BAIAP2L2 p.Asn340Ser Uncertain significance Single submitter
- BAIAP2L2 p.Asp290His Uncertain significance Single submitter
- BAIAP2L2 p.Asp435Gly Uncertain significance Single submitter
- BAIAP2L2 p.Asp88Gly Uncertain significance Single submitter
- BAIAP2L2 p.Cys136Tyr Uncertain significance Single submitter
- BAIAP2L2 p.Gln500Arg Uncertain significance Single submitter
- BAIAP2L2 p.Gln7Glu Uncertain significance Single submitter
- BAIAP2L2 p.Glu177Gln Uncertain significance Single submitter
- BAIAP2L2 p.Glu262Asp Uncertain significance Single submitter
- BAIAP2L2 p.Glu379Lys Uncertain significance Single submitter
- BAIAP2L2 p.Glu46Lys Uncertain significance Single submitter
- BAIAP2L2 p.Glu49Lys Uncertain significance Single submitter
- BAIAP2L2 p.Gly233Arg Uncertain significance Single submitter
- BAIAP2L2 p.Gly325Ser Uncertain significance Single submitter
- BAIAP2L2 p.Gly362Ser Uncertain significance Single submitter
- BAIAP2L2 p.His270Gln Uncertain significance Single submitter
- BAIAP2L2 p.His42Asn Uncertain significance Single submitter
- BAIAP2L2 p.Ile19Val Uncertain significance Single submitter
- BAIAP2L2 p.Ile519Ser Uncertain significance Single submitter
- BAIAP2L2 p.Ile70Thr Uncertain significance Single submitter
- BAIAP2L2 p.Leu161Pro Uncertain significance Single submitter
- BAIAP2L2 p.Leu192Pro Uncertain significance Single submitter
- BAIAP2L2 p.Leu239Pro Uncertain significance Single submitter
- BAIAP2L2 p.Leu294Pro Uncertain significance Single submitter
- BAIAP2L2 p.Leu44Val Uncertain significance Single submitter
- BAIAP2L2 p.Leu63Pro Uncertain significance Single submitter
- BAIAP2L2 p.Lys116Arg Uncertain significance Single submitter
- BAIAP2L2 p.Lys181Arg Uncertain significance Single submitter
- BAIAP2L2 p.Met13Ile Uncertain significance Single submitter
- BAIAP2L2 p.Met13Val Uncertain significance Single submitter
- BAIAP2L2 p.Met20Thr Uncertain significance Single submitter
- BAIAP2L2 p.Met255Arg Uncertain significance Single submitter
- BAIAP2L2 p.Met393Val Uncertain significance Single submitter
- BAIAP2L2 p.Phe316Ser Uncertain significance Single submitter
- BAIAP2L2 p.Pro226Leu Uncertain significance Single submitter
- BAIAP2L2 p.Pro242Ser Uncertain significance Single submitter
- BAIAP2L2 p.Pro259Leu Uncertain significance Single submitter
- BAIAP2L2 p.Pro295Arg Uncertain significance Single submitter
- BAIAP2L2 p.Pro320Arg Uncertain significance Single submitter
- BAIAP2L2 p.Pro3Ser Uncertain significance Single submitter
- BAIAP2L2 p.Pro423Thr Uncertain significance Single submitter
- BAIAP2L2 p.Pro437Leu Uncertain significance Single submitter
- BAIAP2L2 p.Ser172Arg Uncertain significance Single submitter
- BAIAP2L2 p.Ser225Thr Uncertain significance Single submitter
- BAIAP2L2 p.Ser285Ala Uncertain significance Single submitter
- BAIAP2L2 p.Ser79Pro Uncertain significance Single submitter
- BAIAP2L2 p.Trp376Cys Uncertain significance Single submitter
- BAIAP2L2 p.Val151Leu Uncertain significance Single submitter
Predictors split 54
The independent predictors disagree with each other — read with care.
- BAIAP2L2 p.Ala222Thr Uncertain significance Single submitter
- BAIAP2L2 p.Ala26Thr Uncertain significance Single submitter
- BAIAP2L2 p.Ala326Thr Uncertain significance Single submitter
- BAIAP2L2 p.Ala331Thr Uncertain significance Single submitter
- BAIAP2L2 p.Ala380Val Uncertain significance Single submitter
- BAIAP2L2 p.Ala47Val Uncertain significance Single submitter
- BAIAP2L2 p.Ala62Thr Uncertain significance Single submitter
- BAIAP2L2 p.Arg228Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg247Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg267Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg269Gln Uncertain significance Single submitter
- BAIAP2L2 p.Arg291His Uncertain significance Single submitter
- BAIAP2L2 p.Arg296Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg296Leu Uncertain significance Single submitter
- BAIAP2L2 p.Arg39Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg39His Uncertain significance Single submitter
- BAIAP2L2 p.Arg452Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg454Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg454His Uncertain significance Single submitter
- BAIAP2L2 p.Arg458Gln Uncertain significance Single submitter
- BAIAP2L2 p.Arg462Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg462His Uncertain significance Single submitter
- BAIAP2L2 p.Arg475Cys Uncertain significance Single submitter
- BAIAP2L2 p.Arg476Cys Uncertain significance Single submitter
- BAIAP2L2 p.Asn211Ile Uncertain significance Single submitter
- BAIAP2L2 p.Asn314Ile Uncertain significance Single submitter
- BAIAP2L2 p.Asn340Lys Uncertain significance Single submitter
- BAIAP2L2 p.Asn521Ser Uncertain significance Single submitter
- BAIAP2L2 p.Gln210Arg Uncertain significance Single submitter
- BAIAP2L2 p.Glu125Gln Uncertain significance Single submitter
- BAIAP2L2 p.Glu278Lys Uncertain significance Single submitter
- BAIAP2L2 p.Glu445Lys Uncertain significance Single submitter
- BAIAP2L2 p.Leu294Met Uncertain significance Single submitter
- BAIAP2L2 p.Leu303Phe Uncertain significance Single submitter
- BAIAP2L2 p.Met143Val Uncertain significance Single submitter
- BAIAP2L2 p.Phe168Leu Uncertain significance Single submitter
- BAIAP2L2 p.Pro244His Uncertain significance Single submitter
- BAIAP2L2 p.Pro250Leu Uncertain significance Single submitter
- BAIAP2L2 p.Pro298Leu Uncertain significance Single submitter
- BAIAP2L2 p.Pro466Ser Uncertain significance Single submitter
- BAIAP2L2 p.Pro472Arg Uncertain significance Single submitter
- BAIAP2L2 p.Pro517Arg Uncertain significance Single submitter
- BAIAP2L2 p.Ser138Cys Uncertain significance Single submitter
- BAIAP2L2 p.Ser274Cys Uncertain significance Single submitter
- BAIAP2L2 p.Ser301Phe Uncertain significance Single submitter
- BAIAP2L2 p.Ser302Trp Uncertain significance Single submitter
- BAIAP2L2 p.Ser372Cys Uncertain significance Single submitter
- BAIAP2L2 p.Ser493Phe Uncertain significance Single submitter
- BAIAP2L2 p.Thr249Met Uncertain significance Single submitter
- BAIAP2L2 p.Thr297Met Uncertain significance Single submitter
- BAIAP2L2 p.Thr394Ser Uncertain significance Single submitter
- BAIAP2L2 p.Val31Met Uncertain significance Single submitter
- BAIAP2L2 p.Val351Met Uncertain significance Single submitter
- BAIAP2L2 p.Val50Ile Uncertain significance Single submitter
All BAIAP2L2 variants
Likely benign 6
- p.Ala463= Single submitter
- p.Asp431Asn Single submitter
- p.Glu353= Single submitter
- p.Gly306Ser Single submitter
- p.Gly99Asp Single submitter
- p.Ser406= Single submitter
Uncertain significance 113
- p.Ala163Val Single submitter ⚠
- p.Ala222Thr Single submitter ⚠
- p.Ala26Thr Single submitter ⚠
- p.Ala326Thr Single submitter ⚠
- p.Ala331Thr Single submitter ⚠
- p.Ala380Val Single submitter ⚠
- p.Ala47Val Single submitter ⚠
- p.Ala62Thr Single submitter ⚠
- p.Ala62Val Single submitter ⚠
- p.Arg160Gln Single submitter ⚠
- p.Arg228Cys Single submitter ⚠
- p.Arg228Ser Single submitter ⚠
- p.Arg247Cys Single submitter ⚠
- p.Arg267Cys Single submitter ⚠
- p.Arg269Gln Single submitter ⚠
- p.Arg291His Single submitter ⚠
- p.Arg296Cys Single submitter ⚠
- p.Arg296Leu Single submitter ⚠
- p.Arg296Pro Single submitter ⚠
- p.Arg39Cys Single submitter ⚠
- p.Arg39His Single submitter ⚠
- p.Arg452Cys Single submitter ⚠
- p.Arg454Cys Single submitter ⚠
- p.Arg454His Single submitter ⚠
- p.Arg458Gln Single submitter ⚠
- p.Arg462Cys Single submitter ⚠
- p.Arg462His Single submitter ⚠
- p.Arg475Cys Single submitter ⚠
- p.Arg475His Single submitter ⚠
- p.Arg476Cys Single submitter ⚠
- p.Arg476His Single submitter ⚠
- p.Arg523His Single submitter ⚠
- p.Arg61His Single submitter ⚠
- p.Asn196Asp Single submitter ⚠
- p.Asn211Ile Single submitter ⚠
- p.Asn24Lys Single submitter ⚠
- p.Asn314Ile Single submitter ⚠
- p.Asn340Lys Single submitter ⚠
- p.Asn340Ser Single submitter ⚠
- p.Asn521Ser Single submitter ⚠
- p.Asp290His Single submitter ⚠
- p.Asp435Gly Single submitter ⚠
- p.Asp88Gly Single submitter ⚠
- p.Cys136Tyr Single submitter ⚠
- p.Gln210Arg Single submitter ⚠
- p.Gln500Arg Single submitter ⚠
- p.Gln7Glu Single submitter ⚠
- p.Glu125Gln Single submitter ⚠
- p.Glu177Gln Single submitter ⚠
- p.Glu262Asp Single submitter ⚠
- p.Glu278Lys Single submitter ⚠
- p.Glu379Lys Single submitter ⚠
- p.Glu445Lys Single submitter ⚠
- p.Glu46Lys Single submitter ⚠
- p.Glu49Lys Single submitter ⚠
- p.Gly233Arg Single submitter ⚠
- p.Gly325Ser Single submitter ⚠
- p.Gly362Ser Single submitter ⚠
- p.His270Gln Single submitter ⚠
- p.His42Asn Single submitter ⚠
- p.Ile19Val Single submitter ⚠
- p.Ile519Ser Single submitter ⚠
- p.Ile70Thr Single submitter ⚠
- p.Leu161Pro Single submitter ⚠
- p.Leu192Pro Single submitter ⚠
- p.Leu239Pro Single submitter ⚠
- p.Leu294Met Single submitter ⚠
- p.Leu294Pro Single submitter ⚠
- p.Leu303Phe Single submitter ⚠
- p.Leu44Val Single submitter ⚠
- p.Leu63Pro Single submitter ⚠
- p.Lys116Arg Single submitter ⚠
- p.Lys181Arg Single submitter ⚠
- p.Met13Ile Single submitter ⚠
- p.Met13Val Single submitter ⚠
- p.Met143Val Single submitter ⚠
- p.Met20Thr Single submitter ⚠
- p.Met255Arg Single submitter ⚠
- p.Met393Val Single submitter ⚠
- p.Phe168Leu Single submitter ⚠
- p.Phe316Ser Single submitter ⚠
- p.Pro226Leu Single submitter ⚠
- p.Pro242Ser Single submitter ⚠
- p.Pro244His Single submitter ⚠
- p.Pro250Leu Single submitter ⚠
- p.Pro259Leu Single submitter ⚠
- p.Pro295Arg Single submitter ⚠
- p.Pro298Leu Single submitter ⚠
- p.Pro320Arg Single submitter ⚠
- p.Pro3Ser Single submitter ⚠
- p.Pro423Thr Single submitter ⚠
- p.Pro437Leu Single submitter ⚠
- p.Pro466Ser Single submitter ⚠
- p.Pro472Arg Single submitter ⚠
- p.Pro517Arg Single submitter ⚠
- p.Ser138Cys Single submitter ⚠
- p.Ser172Arg Single submitter ⚠
- p.Ser225Thr Single submitter ⚠
- p.Ser274Cys Single submitter ⚠
- p.Ser285Ala Single submitter ⚠
- p.Ser301Phe Single submitter ⚠
- p.Ser302Trp Single submitter ⚠
- p.Ser372Cys Single submitter ⚠
- p.Ser493Phe Single submitter ⚠
- p.Ser79Pro Single submitter ⚠
- p.Thr249Met Single submitter ⚠
- p.Thr297Met Single submitter ⚠
- p.Thr394Ser Single submitter ⚠
- p.Trp376Cys Single submitter ⚠
- p.Val151Leu Single submitter ⚠
- p.Val31Met Single submitter ⚠
- p.Val351Met Single submitter ⚠
- p.Val50Ile Single submitter ⚠