BANF2 — 8 ClinVar variants
All ClinVar germline BANF2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 8 flagged for review →
8 Uncertain significance
Full BANF2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 8
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 7
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- BANF2 p.Ala58Asp Uncertain significance Single submitter
- BANF2 p.Ala87Thr Uncertain significance Single submitter
- BANF2 p.Asn56Lys Uncertain significance Single submitter
- BANF2 p.Gln77Lys Uncertain significance Single submitter
- BANF2 p.Glu59Lys Uncertain significance Single submitter
- BANF2 p.His29Tyr Uncertain significance Single submitter
- BANF2 p.Val36Ala Uncertain significance Single submitter
Predictors split 1
The independent predictors disagree with each other — read with care.
All BANF2 variants
Uncertain significance 8
- p.Ala58Asp Single submitter ⚠
- p.Ala87Thr Single submitter ⚠
- p.Asn56Lys Single submitter ⚠
- p.Gln77Lys Single submitter ⚠
- p.Glu59Lys Single submitter ⚠
- p.His29Tyr Single submitter ⚠
- p.Met53Ile Single submitter ⚠
- p.Val36Ala Single submitter ⚠