BATF2 — 47 ClinVar variants
All ClinVar germline BATF2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 45 flagged for review →
2 Likely benign · 45 Uncertain significance
Full BATF2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 45
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 27
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- BATF2 p.Ala178Asp Uncertain significance Single submitter
- BATF2 p.Ala29Val Uncertain significance Single submitter
- BATF2 p.Ala31Thr Uncertain significance Single submitter
- BATF2 p.Arg28Trp Uncertain significance Single submitter
- BATF2 p.Arg82His Uncertain significance Single submitter
- BATF2 p.Asn7Ser Uncertain significance Single submitter
- BATF2 p.Asn7Tyr Uncertain significance Single submitter
- BATF2 p.Asp87Asn Uncertain significance Single submitter
- BATF2 p.Gln186Lys Uncertain significance Single submitter
- BATF2 p.Gln25Glu Uncertain significance Single submitter
- BATF2 p.Gly220Glu Uncertain significance Single submitter
- BATF2 p.Gly8Glu Uncertain significance Single submitter
- BATF2 p.His143Tyr Uncertain significance Single submitter
- BATF2 p.Phe274Tyr Uncertain significance Single submitter
- BATF2 p.Pro127Leu Uncertain significance Single submitter
- BATF2 p.Pro132Thr Uncertain significance Single submitter
- BATF2 p.Pro135Leu Uncertain significance Single submitter
- BATF2 p.Pro138Leu Uncertain significance Single submitter
- BATF2 p.Pro140Ser Uncertain significance Single submitter
- BATF2 p.Pro142Ala Uncertain significance Single submitter
- BATF2 p.Pro226Ala Uncertain significance Single submitter
- BATF2 p.Pro226Ser Uncertain significance Single submitter
- BATF2 p.Pro265Leu Uncertain significance Single submitter
- BATF2 p.Ser179Leu Uncertain significance Single submitter
- BATF2 p.Ser34Gly Uncertain significance Single submitter
- BATF2 p.Thr200Met Uncertain significance Single submitter
- BATF2 p.Val168Leu Uncertain significance Single submitter
Predictors split 18
The independent predictors disagree with each other — read with care.
- BATF2 p.Arg28Gln Uncertain significance Single submitter
- BATF2 p.Arg33Gln Uncertain significance Single submitter
- BATF2 p.Arg75Trp Uncertain significance Single submitter
- BATF2 p.Asp43Asn Uncertain significance Single submitter
- BATF2 p.Asp55Gly Uncertain significance Single submitter
- BATF2 p.Asp55Val Uncertain significance Single submitter
- BATF2 p.Gln64His Uncertain significance Single submitter
- BATF2 p.His115Tyr Uncertain significance Single submitter
- BATF2 p.His38Tyr Uncertain significance Single submitter
- BATF2 p.Leu149Phe Uncertain significance Single submitter
- BATF2 p.Leu175Phe Uncertain significance Single submitter
- BATF2 p.Lys41Glu Uncertain significance Single submitter
- BATF2 p.Pro154His Uncertain significance Single submitter
- BATF2 p.Ser147Arg Uncertain significance Single submitter
- BATF2 p.Ser190Cys Uncertain significance Single submitter
- BATF2 p.Ser237Asn Uncertain significance Single submitter
- BATF2 p.Ser51Pro Uncertain significance Single submitter
- BATF2 p.Thr126Ile Uncertain significance Single submitter
All BATF2 variants
Likely benign 2
- p.Arg75Gln Single submitter
- p.Ser92Leu Single submitter
Uncertain significance 45
- p.Ala178Asp Single submitter ⚠
- p.Ala29Val Single submitter ⚠
- p.Ala31Thr Single submitter ⚠
- p.Arg28Gln Single submitter ⚠
- p.Arg28Trp Single submitter ⚠
- p.Arg33Gln Single submitter ⚠
- p.Arg75Trp Single submitter ⚠
- p.Arg82His Single submitter ⚠
- p.Asn7Ser Single submitter ⚠
- p.Asn7Tyr Single submitter ⚠
- p.Asp43Asn Single submitter ⚠
- p.Asp55Gly Single submitter ⚠
- p.Asp55Val Single submitter ⚠
- p.Asp87Asn Single submitter ⚠
- p.Gln186Lys Single submitter ⚠
- p.Gln25Glu Single submitter ⚠
- p.Gln64His Single submitter ⚠
- p.Gly220Glu Single submitter ⚠
- p.Gly8Glu Single submitter ⚠
- p.His115Tyr Single submitter ⚠
- p.His143Tyr Single submitter ⚠
- p.His38Tyr Single submitter ⚠
- p.Leu149Phe Single submitter ⚠
- p.Leu175Phe Single submitter ⚠
- p.Lys41Glu Single submitter ⚠
- p.Phe274Tyr Single submitter ⚠
- p.Pro127Leu Single submitter ⚠
- p.Pro132Thr Single submitter ⚠
- p.Pro135Leu Single submitter ⚠
- p.Pro138Leu Single submitter ⚠
- p.Pro140Ser Single submitter ⚠
- p.Pro142Ala Single submitter ⚠
- p.Pro154His Single submitter ⚠
- p.Pro226Ala Single submitter ⚠
- p.Pro226Ser Single submitter ⚠
- p.Pro265Leu Single submitter ⚠
- p.Ser147Arg Single submitter ⚠
- p.Ser179Leu Single submitter ⚠
- p.Ser190Cys Single submitter ⚠
- p.Ser237Asn Single submitter ⚠
- p.Ser34Gly Single submitter ⚠
- p.Ser51Pro Single submitter ⚠
- p.Thr126Ile Single submitter ⚠
- p.Thr200Met Single submitter ⚠
- p.Val168Leu Single submitter ⚠