Sugi Variant

Sugi Variant/BDP1

BDP1 — 611 ClinVar variants

All ClinVar germline BDP1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 341 flagged for review →

3 Likely pathogenic · 13 Conflicting · 133 Benign · 4 Benign/Likely benign · 142 Likely benign · 316 Uncertain significance

Full BDP1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 341

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors vs ClinVar 1

ClinVar calls these pathogenic, but the computational predictors lean tolerated — the highest-value review flag.

Predictors agree, ClinVar conflicts 8

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 200

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 200

Predictors split 132

The independent predictors disagree with each other — read with care.

All BDP1 variants

Likely pathogenic 3

Conflicting classifications of pathogenicity 13

Benign 133

Benign/Likely benign 4

Likely benign 142

Uncertain significance 316

Showing the top 300 by review status; the full set is in the sitemap.