CABP5 — 35 ClinVar variants
All ClinVar germline CABP5 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 32 flagged for review →
2 Likely benign · 33 Uncertain significance
Full CABP5 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 32
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 22
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CABP5 p.Ala8Thr Uncertain significance Single submitter
- CABP5 p.Arg21Gln Uncertain significance Single submitter
- CABP5 p.Arg58Lys Uncertain significance Single submitter
- CABP5 p.Arg77Cys Uncertain significance Single submitter
- CABP5 p.Arg83His Uncertain significance Single submitter
- CABP5 p.Asp41Asn Uncertain significance Single submitter
- CABP5 p.Asp45Gly Uncertain significance Single submitter
- CABP5 p.Glu146Gln Uncertain significance Single submitter
- CABP5 p.Glu153Asp Uncertain significance Single submitter
- CABP5 p.Gly15Arg Uncertain significance Single submitter
- CABP5 p.Gly54Glu Uncertain significance Single submitter
- CABP5 p.Gly61Cys Uncertain significance Single submitter
- CABP5 p.Gly6Val Uncertain significance Single submitter
- CABP5 p.Leu56Val Uncertain significance Single submitter
- CABP5 p.Met60Lys Uncertain significance Single submitter
- CABP5 p.Met93Ile Uncertain significance Single submitter
- CABP5 p.Phe3Ile Uncertain significance Single submitter
- CABP5 p.Pro64Leu Uncertain significance Single submitter
- CABP5 p.Thr119Met Uncertain significance Single submitter
- CABP5 p.Thr94Ser Uncertain significance Single submitter
- CABP5 p.Val162Ala Uncertain significance Single submitter
- CABP5 p.Val168Leu Uncertain significance Single submitter
Predictors split 10
The independent predictors disagree with each other — read with care.
- CABP5 p.Ala113Gly Uncertain significance Single submitter
- CABP5 p.Arg141Trp Uncertain significance Single submitter
- CABP5 p.Arg145Trp Uncertain significance Single submitter
- CABP5 p.Arg152Trp Uncertain significance Single submitter
- CABP5 p.Asn79Ile Uncertain significance Single submitter
- CABP5 p.Glu124Gly Uncertain significance Single submitter
- CABP5 p.Glu165Ala Uncertain significance Single submitter
- CABP5 p.Glu29Ala Uncertain significance Single submitter
- CABP5 p.Glu66Gln Uncertain significance Single submitter
- CABP5 p.Ile70Thr Likely benign Single submitter
All CABP5 variants
Likely benign 2
- p.Arg152Gln Single submitter
- p.Ile70Thr Single submitter ⚠
Uncertain significance 33
- p.Ala113Gly Single submitter ⚠
- p.Ala8Thr Single submitter ⚠
- p.Arg141Trp Single submitter ⚠
- p.Arg145Trp Single submitter ⚠
- p.Arg152Trp Single submitter ⚠
- p.Arg173Leu Single submitter
- p.Arg21Gln Single submitter ⚠
- p.Arg58Lys Single submitter ⚠
- p.Arg77Cys Single submitter ⚠
- p.Arg83His Single submitter ⚠
- p.Asn79Ile Single submitter ⚠
- p.Asp41Asn Single submitter ⚠
- p.Asp45Gly Single submitter ⚠
- p.Glu124Gly Single submitter ⚠
- p.Glu146Gln Single submitter ⚠
- p.Glu153Asp Single submitter ⚠
- p.Glu165Ala Single submitter ⚠
- p.Glu29Ala Single submitter ⚠
- p.Glu66Gln Single submitter ⚠
- p.Gly15Arg Single submitter ⚠
- p.Gly54Glu Single submitter ⚠
- p.Gly61Cys Single submitter ⚠
- p.Gly6Val Single submitter ⚠
- p.Ile10Met Single submitter
- p.Leu56Val Single submitter ⚠
- p.Met60Lys Single submitter ⚠
- p.Met93Ile Single submitter ⚠
- p.Phe3Ile Single submitter ⚠
- p.Pro64Leu Single submitter ⚠
- p.Thr119Met Single submitter ⚠
- p.Thr94Ser Single submitter ⚠
- p.Val162Ala Single submitter ⚠
- p.Val168Leu Single submitter ⚠