CAMKMT — 63 ClinVar variants
All ClinVar germline CAMKMT variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 57 flagged for review →
1 Benign · 5 Likely benign · 57 Uncertain significance
Full CAMKMT gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 57
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 32
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CAMKMT p.Ala16Thr Uncertain significance Single submitter
- CAMKMT p.Ala22Ser Uncertain significance Single submitter
- CAMKMT p.Ala34Glu Uncertain significance Single submitter
- CAMKMT p.Asn106His Uncertain significance Single submitter
- CAMKMT p.Asn266Ser Uncertain significance Single submitter
- CAMKMT p.Asp217Gly Uncertain significance Single submitter
- CAMKMT p.Asp217Tyr Uncertain significance Single submitter
- CAMKMT p.Asp7His Uncertain significance Single submitter
- CAMKMT p.Gln188His Uncertain significance Single submitter
- CAMKMT p.Glu84Asp Uncertain significance Single submitter
- CAMKMT p.Gly11Ser Uncertain significance Single submitter
- CAMKMT p.Gly29Arg Uncertain significance Single submitter
- CAMKMT p.His105Arg Uncertain significance Single submitter
- CAMKMT p.His141Tyr Uncertain significance Single submitter
- CAMKMT p.His59Leu Uncertain significance Single submitter
- CAMKMT p.Ile191Val Uncertain significance Single submitter
- CAMKMT p.Ile247Lys Uncertain significance Single submitter
- CAMKMT p.Ile306Leu Uncertain significance Single submitter
- CAMKMT p.Ile306Met Uncertain significance Single submitter
- CAMKMT p.Leu175Val Uncertain significance Single submitter
- CAMKMT p.Lys172Glu Uncertain significance Single submitter
- CAMKMT p.Lys204Thr Uncertain significance Single submitter
- CAMKMT p.Met164Thr Uncertain significance Single submitter
- CAMKMT p.Pro129Ser Uncertain significance Single submitter
- CAMKMT p.Pro314Ser Uncertain significance Single submitter
- CAMKMT p.Pro35Arg Uncertain significance Single submitter
- CAMKMT p.Pro35Thr Uncertain significance Single submitter
- CAMKMT p.Ser33Leu Uncertain significance Single submitter
- CAMKMT p.Ser61Pro Uncertain significance Single submitter
- CAMKMT p.Thr267Ala Uncertain significance Single submitter
- CAMKMT p.Thr26Ser Uncertain significance Single submitter
- CAMKMT p.Val62Ile Uncertain significance Single submitter
Predictors split 25
The independent predictors disagree with each other — read with care.
- CAMKMT p.Ala183Thr Uncertain significance Single submitter
- CAMKMT p.Ala38Gly Uncertain significance Single submitter
- CAMKMT p.Arg211Gln Uncertain significance Single submitter
- CAMKMT p.Arg40Gly Uncertain significance Single submitter
- CAMKMT p.Cys138Arg Uncertain significance Single submitter
- CAMKMT p.Gln283Arg Uncertain significance Single submitter
- CAMKMT p.Gly198Ser Uncertain significance Single submitter
- CAMKMT p.Leu110Trp Uncertain significance Single submitter
- CAMKMT p.Leu139Phe Uncertain significance Single submitter
- CAMKMT p.Leu163Phe Uncertain significance Single submitter
- CAMKMT p.Leu268Val Uncertain significance Single submitter
- CAMKMT p.Leu316Met Uncertain significance Single submitter
- CAMKMT p.Leu317Phe Uncertain significance Single submitter
- CAMKMT p.Pro304Leu Uncertain significance Single submitter
- CAMKMT p.Ser207Arg Uncertain significance Single submitter
- CAMKMT p.Ser207Thr Uncertain significance Single submitter
- CAMKMT p.Ser242Gly Uncertain significance Single submitter
- CAMKMT p.Thr10Ile Uncertain significance Single submitter
- CAMKMT p.Thr13Ile Uncertain significance Single submitter
- CAMKMT p.Thr192Ile Uncertain significance Single submitter
- CAMKMT p.Tyr239His Uncertain significance Single submitter
- CAMKMT p.Val115Phe Uncertain significance Single submitter
- CAMKMT p.Val187Leu Uncertain significance Single submitter
- CAMKMT p.Val199Met Uncertain significance Single submitter
- CAMKMT p.Val32Ile Uncertain significance Single submitter
All CAMKMT variants
Benign 1
- p.Ile282= Multiple submitters
Likely benign 5
- p.Ala147Asp Single submitter
- p.Ala257= Single submitter
- p.Cys281Ser Single submitter
- p.Pro304= Single submitter
- p.Val85Ala Single submitter
Uncertain significance 57
- p.Ala16Thr Single submitter ⚠
- p.Ala183Thr Single submitter ⚠
- p.Ala22Ser Single submitter ⚠
- p.Ala34Glu Single submitter ⚠
- p.Ala38Gly Single submitter ⚠
- p.Arg211Gln Single submitter ⚠
- p.Arg40Gly Single submitter ⚠
- p.Asn106His Single submitter ⚠
- p.Asn266Ser Single submitter ⚠
- p.Asp217Gly Single submitter ⚠
- p.Asp217Tyr Single submitter ⚠
- p.Asp7His Single submitter ⚠
- p.Cys138Arg Single submitter ⚠
- p.Gln188His Single submitter ⚠
- p.Gln283Arg Single submitter ⚠
- p.Glu84Asp Single submitter ⚠
- p.Gly11Ser Single submitter ⚠
- p.Gly198Ser Single submitter ⚠
- p.Gly29Arg Single submitter ⚠
- p.His105Arg Single submitter ⚠
- p.His141Tyr Single submitter ⚠
- p.His59Leu Single submitter ⚠
- p.Ile191Val Single submitter ⚠
- p.Ile247Lys Single submitter ⚠
- p.Ile306Leu Single submitter ⚠
- p.Ile306Met Single submitter ⚠
- p.Leu110Trp Single submitter ⚠
- p.Leu139Phe Single submitter ⚠
- p.Leu163Phe Single submitter ⚠
- p.Leu175Val Single submitter ⚠
- p.Leu268Val Single submitter ⚠
- p.Leu316Met Single submitter ⚠
- p.Leu317Phe Single submitter ⚠
- p.Lys172Glu Single submitter ⚠
- p.Lys204Thr Single submitter ⚠
- p.Met164Thr Single submitter ⚠
- p.Pro129Ser Single submitter ⚠
- p.Pro304Leu Single submitter ⚠
- p.Pro314Ser Single submitter ⚠
- p.Pro35Arg Single submitter ⚠
- p.Pro35Thr Single submitter ⚠
- p.Ser207Arg Single submitter ⚠
- p.Ser207Thr Single submitter ⚠
- p.Ser242Gly Single submitter ⚠
- p.Ser33Leu Single submitter ⚠
- p.Ser61Pro Single submitter ⚠
- p.Thr10Ile Single submitter ⚠
- p.Thr13Ile Single submitter ⚠
- p.Thr192Ile Single submitter ⚠
- p.Thr267Ala Single submitter ⚠
- p.Thr26Ser Single submitter ⚠
- p.Tyr239His Single submitter ⚠
- p.Val115Phe Single submitter ⚠
- p.Val187Leu Single submitter ⚠
- p.Val199Met Single submitter ⚠
- p.Val32Ile Single submitter ⚠
- p.Val62Ile Single submitter ⚠