CAMLG — 33 ClinVar variants
All ClinVar germline CAMLG variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 33 flagged for review →
33 Uncertain significance
Full CAMLG gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 33
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 17
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CAMLG p.Arg149Cys Uncertain significance Single submitter
- CAMLG p.Arg84Gln Uncertain significance Single submitter
- CAMLG p.Asn128Thr Uncertain significance Single submitter
- CAMLG p.Asp178Asn Uncertain significance Single submitter
- CAMLG p.Gln133His Uncertain significance Single submitter
- CAMLG p.Gln176Arg Uncertain significance Single submitter
-
CAMLG p.Gly251Glu
Uncertain significance
Single submitter
congenital disorder of glycosylation, type IIz
- CAMLG p.Gly88Asp Uncertain significance Single submitter
- CAMLG p.Ile170Met Uncertain significance Single submitter
-
CAMLG p.Leu220Ser
Uncertain significance
Single submitter
congenital disorder of glycosylation, type IIz
- CAMLG p.Leu73Pro Uncertain significance Single submitter
- CAMLG p.Lys35Arg Uncertain significance Single submitter
- CAMLG p.Met163Val Uncertain significance Single submitter
- CAMLG p.Ser61Gly Uncertain significance Single submitter
- CAMLG p.Thr181Ile Uncertain significance Single submitter
- CAMLG p.Thr96Ala Uncertain significance Single submitter
- CAMLG p.Thr96Pro Uncertain significance Single submitter
Predictors split 16
The independent predictors disagree with each other — read with care.
- CAMLG p.Ala223Val Uncertain significance Single submitter
- CAMLG p.Arg132Trp Uncertain significance Single submitter
- CAMLG p.Asp186Tyr Uncertain significance Single submitter
- CAMLG p.Cys208Trp Uncertain significance Single submitter
- CAMLG p.His285Asp Uncertain significance Single submitter
- CAMLG p.Leu165Arg Uncertain significance Single submitter
- CAMLG p.Met48Ile Uncertain significance Single submitter
- CAMLG p.Phe214Tyr Uncertain significance Single submitter
- CAMLG p.Phe279Leu Uncertain significance Single submitter
- CAMLG p.Pro232Leu Uncertain significance Single submitter
- CAMLG p.Ser143Leu Uncertain significance Single submitter
- CAMLG p.Ser187Phe Uncertain significance Single submitter
- CAMLG p.Ser61Cys Uncertain significance Single submitter
- CAMLG p.Ser70Asn Uncertain significance Single submitter
- CAMLG p.Tyr264Cys Uncertain significance Single submitter
- CAMLG p.Tyr290Cys Uncertain significance Single submitter
All CAMLG variants
Uncertain significance 33
- p.Ala223Val Single submitter ⚠
- p.Arg132Trp Single submitter ⚠
- p.Arg149Cys Single submitter ⚠
- p.Arg84Gln Single submitter ⚠
- p.Asn128Thr Single submitter ⚠
- p.Asp178Asn Single submitter ⚠
- p.Asp186Tyr Single submitter ⚠
- p.Cys208Trp Single submitter ⚠
- p.Gln133His Single submitter ⚠
- p.Gln176Arg Single submitter ⚠
- p.Gly251Glu Single submitter congenital disorder of glycosylation, type IIz ⚠
- p.Gly88Asp Single submitter ⚠
- p.His285Asp Single submitter ⚠
- p.Ile170Met Single submitter ⚠
- p.Leu165Arg Single submitter ⚠
- p.Leu220Ser Single submitter congenital disorder of glycosylation, type IIz ⚠
- p.Leu73Pro Single submitter ⚠
- p.Lys35Arg Single submitter ⚠
- p.Met163Val Single submitter ⚠
- p.Met48Ile Single submitter ⚠
- p.Phe214Tyr Single submitter ⚠
- p.Phe279Leu Single submitter ⚠
- p.Pro232Leu Single submitter ⚠
- p.Ser143Leu Single submitter ⚠
- p.Ser187Phe Single submitter ⚠
- p.Ser61Cys Single submitter ⚠
- p.Ser61Gly Single submitter ⚠
- p.Ser70Asn Single submitter ⚠
- p.Thr181Ile Single submitter ⚠
- p.Thr96Ala Single submitter ⚠
- p.Thr96Pro Single submitter ⚠
- p.Tyr264Cys Single submitter ⚠
- p.Tyr290Cys Single submitter ⚠