CAMSAP3 — 181 ClinVar variants
All ClinVar germline CAMSAP3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 167 flagged for review →
6 Benign · 7 Likely benign · 168 Uncertain significance
Full CAMSAP3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 167
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 81
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CAMSAP3 p.Ala1118Thr Uncertain significance Single submitter
- CAMSAP3 p.Ala125Asp Uncertain significance Single submitter
- CAMSAP3 p.Ala188Glu Uncertain significance Single submitter
- CAMSAP3 p.Ala196Pro Uncertain significance Single submitter
- CAMSAP3 p.Ala340Ser Uncertain significance Single submitter
- CAMSAP3 p.Ala443Pro Uncertain significance Single submitter
- CAMSAP3 p.Ala469Val Uncertain significance Single submitter
- CAMSAP3 p.Ala649Gly Uncertain significance Single submitter
- CAMSAP3 p.Ala702Val Uncertain significance Single submitter
- CAMSAP3 p.Ala754Thr Uncertain significance Single submitter
- CAMSAP3 p.Ala760Ser Uncertain significance Single submitter
- CAMSAP3 p.Ala947Val Uncertain significance Single submitter
- CAMSAP3 p.Ala956Val Uncertain significance Single submitter
- CAMSAP3 p.Arg1030Leu Uncertain significance Single submitter
- CAMSAP3 p.Arg1034His Uncertain significance Single submitter
- CAMSAP3 p.Arg218Gln Uncertain significance Single submitter
- CAMSAP3 p.Arg280His Uncertain significance Single submitter
- CAMSAP3 p.Arg283Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg283His Uncertain significance Single submitter
- CAMSAP3 p.Arg336Gln Uncertain significance Single submitter
- CAMSAP3 p.Arg629Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg629His Uncertain significance Single submitter
- CAMSAP3 p.Arg762Gln Uncertain significance Single submitter
- CAMSAP3 p.Arg840Gln Uncertain significance Single submitter
- CAMSAP3 p.Arg840Leu Uncertain significance Single submitter
- CAMSAP3 p.Arg999Leu Uncertain significance Single submitter
- CAMSAP3 p.Asn1057Ser Uncertain significance Single submitter
- CAMSAP3 p.Asn1061Ser Uncertain significance Single submitter
- CAMSAP3 p.Asp329Asn Uncertain significance Single submitter
- CAMSAP3 p.Gln205Glu Uncertain significance Single submitter
- CAMSAP3 p.Gln344Pro Uncertain significance Single submitter
- CAMSAP3 p.Gln639Leu Uncertain significance Single submitter
- CAMSAP3 p.Gln90Pro Uncertain significance Single submitter
- CAMSAP3 p.Glu1058Lys Uncertain significance Single submitter
- CAMSAP3 p.Glu1089Gln Uncertain significance Single submitter
- CAMSAP3 p.Glu1140Lys Uncertain significance Single submitter
- CAMSAP3 p.Glu151Lys Uncertain significance Single submitter
- CAMSAP3 p.Glu339Asp Uncertain significance Single submitter
- CAMSAP3 p.Glu3Ala Uncertain significance Single submitter
- CAMSAP3 p.Glu580Ala Uncertain significance Single submitter
- CAMSAP3 p.Glu608Gly Uncertain significance Single submitter
- CAMSAP3 p.Glu694Gln Uncertain significance Single submitter
- CAMSAP3 p.Glu698Lys Uncertain significance Single submitter
- CAMSAP3 p.Glu732Lys Uncertain significance Single submitter
- CAMSAP3 p.Glu878Asp Uncertain significance Single submitter
- CAMSAP3 p.Glu983Lys Uncertain significance Single submitter
- CAMSAP3 p.Gly1064Arg Uncertain significance Single submitter
- CAMSAP3 p.Gly348Ser Uncertain significance Single submitter
- CAMSAP3 p.Gly664Arg Uncertain significance Single submitter
- CAMSAP3 p.Gly735Arg Uncertain significance Single submitter
- CAMSAP3 p.Gly773Arg Uncertain significance Single submitter
- CAMSAP3 p.Gly866Ser Uncertain significance Single submitter
- CAMSAP3 p.His167Pro Uncertain significance Single submitter
- CAMSAP3 p.Ile624Val Uncertain significance Single submitter
- CAMSAP3 p.Leu1175Pro Uncertain significance Single submitter
- CAMSAP3 p.Met145Ile Uncertain significance Single submitter
- CAMSAP3 p.Met383Val Uncertain significance Single submitter
- CAMSAP3 p.Met386Val Uncertain significance Single submitter
- CAMSAP3 p.Met955Val Uncertain significance Single submitter
- CAMSAP3 p.Pro1075Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro381Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro438Gln Uncertain significance Single submitter
- CAMSAP3 p.Pro521Arg Uncertain significance Single submitter
- CAMSAP3 p.Pro53Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro686Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro692Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro834Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro946Ala Uncertain significance Single submitter
- CAMSAP3 p.Ser1183Leu Uncertain significance Single submitter
- CAMSAP3 p.Ser207Leu Uncertain significance Single submitter
- CAMSAP3 p.Ser712Thr Uncertain significance Single submitter
- CAMSAP3 p.Ser814Leu Uncertain significance Single submitter
- CAMSAP3 p.Thr1016Ala Uncertain significance Single submitter
- CAMSAP3 p.Thr1054Pro Uncertain significance Single submitter
- CAMSAP3 p.Thr795Ser Uncertain significance Single submitter
- CAMSAP3 p.Tyr1188Phe Uncertain significance Single submitter
- CAMSAP3 p.Tyr500His Uncertain significance Single submitter
- CAMSAP3 p.Tyr982Cys Uncertain significance Single submitter
- CAMSAP3 p.Val430Leu Uncertain significance Single submitter
- CAMSAP3 p.Val926Met Uncertain significance Single submitter
- CAMSAP3 p.Val953Leu Uncertain significance Single submitter
Predictors split 86
The independent predictors disagree with each other — read with care.
- CAMSAP3 p.Ala1002Val Uncertain significance Single submitter
- CAMSAP3 p.Ala1098Val Uncertain significance Single submitter
- CAMSAP3 p.Ala1186Thr Uncertain significance Single submitter
- CAMSAP3 p.Ala149Val Uncertain significance Single submitter
- CAMSAP3 p.Ala188Gly Uncertain significance Single submitter
- CAMSAP3 p.Ala202Val Uncertain significance Single submitter
- CAMSAP3 p.Ala217Glu Uncertain significance Single submitter
- CAMSAP3 p.Ala39Val Uncertain significance Single submitter
- CAMSAP3 p.Ala591Asp Uncertain significance Single submitter
- CAMSAP3 p.Ala787Val Uncertain significance Single submitter
- CAMSAP3 p.Ala838Asp Uncertain significance Single submitter
- CAMSAP3 p.Ala838Val Uncertain significance Single submitter
- CAMSAP3 p.Ala939Asp Uncertain significance Single submitter
- CAMSAP3 p.Arg1083Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg1088Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg1088His Uncertain significance Single submitter
- CAMSAP3 p.Arg111Gly Uncertain significance Single submitter
- CAMSAP3 p.Arg111Lys Uncertain significance Single submitter
- CAMSAP3 p.Arg1145His Uncertain significance Single submitter
- CAMSAP3 p.Arg219His Uncertain significance Single submitter
- CAMSAP3 p.Arg399Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg439Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg444Met Uncertain significance Single submitter
- CAMSAP3 p.Arg606Trp Uncertain significance Single submitter
- CAMSAP3 p.Arg678Gln Uncertain significance Single submitter
- CAMSAP3 p.Arg678Trp Uncertain significance Single submitter
- CAMSAP3 p.Arg768His Uncertain significance Single submitter
- CAMSAP3 p.Arg840Trp Uncertain significance Single submitter
- CAMSAP3 p.Arg909Leu Uncertain significance Single submitter
- CAMSAP3 p.Arg912Pro Uncertain significance Single submitter
- CAMSAP3 p.Arg912Trp Uncertain significance Single submitter
- CAMSAP3 p.Arg984Cys Uncertain significance Single submitter
- CAMSAP3 p.Arg984His Uncertain significance Single submitter
- CAMSAP3 p.Asp805Asn Uncertain significance Single submitter
- CAMSAP3 p.Asp992Gly Uncertain significance Single submitter
- CAMSAP3 p.Cys244Trp Uncertain significance Single submitter
- CAMSAP3 p.Glu648Val Uncertain significance Single submitter
- CAMSAP3 p.Glu898Gln Uncertain significance Single submitter
- CAMSAP3 p.Glu916Ala Uncertain significance Single submitter
- CAMSAP3 p.Gly200Val Uncertain significance Single submitter
- CAMSAP3 p.Gly886Arg Uncertain significance Single submitter
- CAMSAP3 p.His467Gln Uncertain significance Single submitter
- CAMSAP3 p.His69Gln Uncertain significance Single submitter
- CAMSAP3 p.Ile1146Phe Uncertain significance Single submitter
- CAMSAP3 p.Leu401Ile Uncertain significance Single submitter
- CAMSAP3 p.Leu426His Uncertain significance Single submitter
- CAMSAP3 p.Leu463Pro Uncertain significance Single submitter
- CAMSAP3 p.Leu56Met Uncertain significance Single submitter
- CAMSAP3 p.Leu574Met Uncertain significance Single submitter
- CAMSAP3 p.Leu688Met Uncertain significance Single submitter
- CAMSAP3 p.Leu706Val Uncertain significance Single submitter
- CAMSAP3 p.Leu794Phe Uncertain significance Single submitter
- CAMSAP3 p.Lys1152Glu Uncertain significance Single submitter
- CAMSAP3 p.Lys507Asn Uncertain significance Single submitter
- CAMSAP3 p.Lys680Gln Uncertain significance Single submitter
- CAMSAP3 p.Met1221Ile Uncertain significance Single submitter
- CAMSAP3 p.Phe684Ile Uncertain significance Single submitter
- CAMSAP3 p.Phe684Ser Uncertain significance Single submitter
- CAMSAP3 p.Pro1101Ser Uncertain significance Single submitter
- CAMSAP3 p.Pro297Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro352Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro442Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro446Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro451Thr Uncertain significance Single submitter
- CAMSAP3 p.Pro555Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro593Gln Uncertain significance Single submitter
- CAMSAP3 p.Pro593Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro734Ser Uncertain significance Single submitter
- CAMSAP3 p.Pro944Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro948Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro954Leu Uncertain significance Single submitter
- CAMSAP3 p.Pro958Leu Uncertain significance Single submitter
- CAMSAP3 p.Ser1176Leu Uncertain significance Single submitter
- CAMSAP3 p.Ser527Leu Uncertain significance Single submitter
- CAMSAP3 p.Ser585Phe Uncertain significance Single submitter
- CAMSAP3 p.Ser601Asn Uncertain significance Single submitter
- CAMSAP3 p.Ser877Trp Uncertain significance Single submitter
- CAMSAP3 p.Thr1192Ala Uncertain significance Single submitter
- CAMSAP3 p.Thr225Met Uncertain significance Single submitter
- CAMSAP3 p.Thr587Met Uncertain significance Single submitter
- CAMSAP3 p.Thr62Ile Uncertain significance Single submitter
- CAMSAP3 p.Thr750Met Uncertain significance Single submitter
- CAMSAP3 p.Thr795Ile Uncertain significance Single submitter
- CAMSAP3 p.Val140Ile Uncertain significance Single submitter
- CAMSAP3 p.Val295Ile Uncertain significance Single submitter
- CAMSAP3 p.Val682Leu Uncertain significance Single submitter
All CAMSAP3 variants
Benign 6
- p.Ala239= Multiple submitters
- p.Arg931Gln Multiple submitters
- p.Pro381= Multiple submitters
- p.Tyr294= Multiple submitters
- c.994+8C>T Single submitter
- p.Thr225= Single submitter
Likely benign 7
- p.Ala943Val Single submitter
- p.Asp687Glu Single submitter
- p.Gly1245Ser Single submitter
- p.Gly1246Ser Single submitter
- p.Gly659Arg Single submitter
- p.Val953Ala Single submitter
- p.Leu1084= No assertion criteria EBV-positive nodal T- and NK-cell lymphoma
Uncertain significance 168
- c.622-299A>G Single submitter
- p.Ala1002Val Single submitter ⚠
- p.Ala1098Val Single submitter ⚠
- p.Ala1118Thr Single submitter ⚠
- p.Ala1186Thr Single submitter ⚠
- p.Ala125Asp Single submitter ⚠
- p.Ala149Val Single submitter ⚠
- p.Ala188Glu Single submitter ⚠
- p.Ala188Gly Single submitter ⚠
- p.Ala196Pro Single submitter ⚠
- p.Ala202Val Single submitter ⚠
- p.Ala217Glu Single submitter ⚠
- p.Ala340Ser Single submitter ⚠
- p.Ala39Val Single submitter ⚠
- p.Ala443Pro Single submitter ⚠
- p.Ala469Val Single submitter ⚠
- p.Ala591Asp Single submitter ⚠
- p.Ala649Gly Single submitter ⚠
- p.Ala702Val Single submitter ⚠
- p.Ala754Thr Single submitter ⚠
- p.Ala760Ser Single submitter ⚠
- p.Ala787Val Single submitter ⚠
- p.Ala838Asp Single submitter ⚠
- p.Ala838Val Single submitter ⚠
- p.Ala939Asp Single submitter ⚠
- p.Ala947Val Single submitter ⚠
- p.Ala956Val Single submitter ⚠
- p.Arg1030Leu Single submitter ⚠
- p.Arg1034His Single submitter ⚠
- p.Arg1083Cys Single submitter ⚠
- p.Arg1088Cys Single submitter ⚠
- p.Arg1088His Single submitter ⚠
- p.Arg111Gly Single submitter ⚠
- p.Arg111Lys Single submitter ⚠
- p.Arg1145His Single submitter ⚠
- p.Arg218Gln Single submitter ⚠
- p.Arg219His Single submitter ⚠
- p.Arg280His Single submitter ⚠
- p.Arg283Cys Single submitter ⚠
- p.Arg283His Single submitter ⚠
- p.Arg336Gln Single submitter ⚠
- p.Arg399Cys Single submitter ⚠
- p.Arg439Cys Single submitter ⚠
- p.Arg444Met Single submitter ⚠
- p.Arg606Trp Single submitter ⚠
- p.Arg629Cys Single submitter ⚠
- p.Arg629His Single submitter ⚠
- p.Arg678Gln Single submitter ⚠
- p.Arg678Trp Single submitter ⚠
- p.Arg762Gln Single submitter ⚠
- p.Arg768His Single submitter ⚠
- p.Arg840Gln Single submitter ⚠
- p.Arg840Leu Single submitter ⚠
- p.Arg840Trp Single submitter ⚠
- p.Arg909Leu Single submitter ⚠
- p.Arg912Pro Single submitter ⚠
- p.Arg912Trp Single submitter ⚠
- p.Arg984Cys Single submitter ⚠
- p.Arg984His Single submitter ⚠
- p.Arg999Leu Single submitter ⚠
- p.Asn1057Ser Single submitter ⚠
- p.Asn1061Ser Single submitter ⚠
- p.Asp329Asn Single submitter ⚠
- p.Asp805Asn Single submitter ⚠
- p.Asp992Gly Single submitter ⚠
- p.Cys244Trp Single submitter ⚠
- p.Gln205Glu Single submitter ⚠
- p.Gln344Pro Single submitter ⚠
- p.Gln639Leu Single submitter ⚠
- p.Gln90Pro Single submitter ⚠
- p.Glu1058Lys Single submitter ⚠
- p.Glu1089Gln Single submitter ⚠
- p.Glu1140Lys Single submitter ⚠
- p.Glu151Lys Single submitter ⚠
- p.Glu339Asp Single submitter ⚠
- p.Glu3Ala Single submitter ⚠
- p.Glu580Ala Single submitter ⚠
- p.Glu608Gly Single submitter ⚠
- p.Glu648Val Single submitter ⚠
- p.Glu694Gln Single submitter ⚠
- p.Glu698Lys Single submitter ⚠
- p.Glu732Lys Single submitter ⚠
- p.Glu878Asp Single submitter ⚠
- p.Glu898Gln Single submitter ⚠
- p.Glu916Ala Single submitter ⚠
- p.Glu983Lys Single submitter ⚠
- p.Gly1064Arg Single submitter ⚠
- p.Gly200Val Single submitter ⚠
- p.Gly348Ser Single submitter ⚠
- p.Gly664Arg Single submitter ⚠
- p.Gly735Arg Single submitter ⚠
- p.Gly773Arg Single submitter ⚠
- p.Gly866Ser Single submitter ⚠
- p.Gly886Arg Single submitter ⚠
- p.His167Pro Single submitter ⚠
- p.His467Gln Single submitter ⚠
- p.His69Gln Single submitter ⚠
- p.Ile1146Phe Single submitter ⚠
- p.Ile624Val Single submitter ⚠
- p.Leu1175Pro Single submitter ⚠
- p.Leu401Ile Single submitter ⚠
- p.Leu426His Single submitter ⚠
- p.Leu463Pro Single submitter ⚠
- p.Leu56Met Single submitter ⚠
- p.Leu574Met Single submitter ⚠
- p.Leu688Met Single submitter ⚠
- p.Leu706Val Single submitter ⚠
- p.Leu794Phe Single submitter ⚠
- p.Lys1152Glu Single submitter ⚠
- p.Lys507Asn Single submitter ⚠
- p.Lys680Gln Single submitter ⚠
- p.Met1221Ile Single submitter ⚠
- p.Met145Ile Single submitter ⚠
- p.Met383Val Single submitter ⚠
- p.Met386Val Single submitter ⚠
- p.Met955Val Single submitter ⚠
- p.Phe684Ile Single submitter ⚠
- p.Phe684Ser Single submitter ⚠
- p.Pro1075Leu Single submitter ⚠
- p.Pro1101Ser Single submitter ⚠
- p.Pro297Leu Single submitter ⚠
- p.Pro352Leu Single submitter ⚠
- p.Pro381Leu Single submitter ⚠
- p.Pro438Gln Single submitter ⚠
- p.Pro442Leu Single submitter ⚠
- p.Pro446Leu Single submitter ⚠
- p.Pro451Thr Single submitter ⚠
- p.Pro521Arg Single submitter ⚠
- p.Pro53Leu Single submitter ⚠
- p.Pro555Leu Single submitter ⚠
- p.Pro593Gln Single submitter ⚠
- p.Pro593Leu Single submitter ⚠
- p.Pro686Leu Single submitter ⚠
- p.Pro692Leu Single submitter ⚠
- p.Pro734Ser Single submitter ⚠
- p.Pro834Leu Single submitter ⚠
- p.Pro944Leu Single submitter ⚠
- p.Pro946Ala Single submitter ⚠
- p.Pro948Leu Single submitter ⚠
- p.Pro954Leu Single submitter ⚠
- p.Pro958Leu Single submitter ⚠
- p.Ser1176Leu Single submitter ⚠
- p.Ser1183Leu Single submitter ⚠
- p.Ser207Leu Single submitter ⚠
- p.Ser527Leu Single submitter ⚠
- p.Ser585Phe Single submitter ⚠
- p.Ser601Asn Single submitter ⚠
- p.Ser712Thr Single submitter ⚠
- p.Ser814Leu Single submitter ⚠
- p.Ser877Trp Single submitter ⚠
- p.Thr1016Ala Single submitter ⚠
- p.Thr1054Pro Single submitter ⚠
- p.Thr1192Ala Single submitter ⚠
- p.Thr225Met Single submitter ⚠
- p.Thr587Met Single submitter ⚠
- p.Thr62Ile Single submitter ⚠
- p.Thr750Met Single submitter ⚠
- p.Thr795Ile Single submitter ⚠
- p.Thr795Ser Single submitter ⚠
- p.Tyr1188Phe Single submitter ⚠
- p.Tyr500His Single submitter ⚠
- p.Tyr982Cys Single submitter ⚠
- p.Val140Ile Single submitter ⚠
- p.Val295Ile Single submitter ⚠
- p.Val430Leu Single submitter ⚠
- p.Val682Leu Single submitter ⚠
- p.Val926Met Single submitter ⚠
- p.Val953Leu Single submitter ⚠