CCDC71L — 61 ClinVar variants
All ClinVar germline CCDC71L variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 61 flagged for review →
61 Uncertain significance
Full CCDC71L gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 61
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 57
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CCDC71L p.Ala117Thr Uncertain significance Single submitter
- CCDC71L p.Ala121Glu Uncertain significance Single submitter
- CCDC71L p.Ala121Gly Uncertain significance Single submitter
- CCDC71L p.Ala129Thr Uncertain significance Single submitter
- CCDC71L p.Ala137Thr Uncertain significance Single submitter
- CCDC71L p.Ala139Val Uncertain significance Single submitter
- CCDC71L p.Ala142Ser Uncertain significance Single submitter
- CCDC71L p.Ala142Thr Uncertain significance Single submitter
- CCDC71L p.Ala15Gly Uncertain significance Single submitter
- CCDC71L p.Ala15Pro Uncertain significance Single submitter
- CCDC71L p.Ala163Val Uncertain significance Single submitter
- CCDC71L p.Ala167Ser Uncertain significance Single submitter
- CCDC71L p.Ala59Ser Uncertain significance Single submitter
- CCDC71L p.Arg118His Uncertain significance Single submitter
- CCDC71L p.Arg123Trp Uncertain significance Single submitter
- CCDC71L p.Arg138Gln Uncertain significance Single submitter
- CCDC71L p.Arg143Ser Uncertain significance Single submitter
- CCDC71L p.Arg148Gln Uncertain significance Single submitter
- CCDC71L p.Arg204Pro Uncertain significance Single submitter
- CCDC71L p.Arg211His Uncertain significance Single submitter
- CCDC71L p.Arg212Lys Uncertain significance Single submitter
- CCDC71L p.Arg212Ser Uncertain significance Single submitter
- CCDC71L p.Arg212Thr Uncertain significance Single submitter
- CCDC71L p.Arg214Cys Uncertain significance Single submitter
- CCDC71L p.Arg21Gln Uncertain significance Single submitter
- CCDC71L p.Arg234Gln Uncertain significance Single submitter
- CCDC71L p.Arg66Cys Uncertain significance Single submitter
- CCDC71L p.Arg66His Uncertain significance Single submitter
- CCDC71L p.Asp110Asn Uncertain significance Single submitter
- CCDC71L p.Asp110Glu Uncertain significance Single submitter
- CCDC71L p.Asp199Asn Uncertain significance Single submitter
- CCDC71L p.Gln215Lys Uncertain significance Single submitter
- CCDC71L p.Glu203Gln Uncertain significance Single submitter
- CCDC71L p.Gly173Arg Uncertain significance Single submitter
- CCDC71L p.Gly30Arg Uncertain significance Single submitter
- CCDC71L p.Gly32Arg Uncertain significance Single submitter
- CCDC71L p.Leu56Pro Uncertain significance Single submitter
- CCDC71L p.Lys85Arg Uncertain significance Single submitter
- CCDC71L p.Met224Ile Uncertain significance Single submitter
- CCDC71L p.Phe25Leu Uncertain significance Single submitter
- CCDC71L p.Pro112Ala Uncertain significance Single submitter
- CCDC71L p.Pro114Ser Uncertain significance Single submitter
- CCDC71L p.Pro13Leu Uncertain significance Single submitter
- CCDC71L p.Pro151Ser Uncertain significance Single submitter
- CCDC71L p.Pro153Leu Uncertain significance Single submitter
- CCDC71L p.Pro156Leu Uncertain significance Single submitter
- CCDC71L p.Pro162Ala Uncertain significance Single submitter
- CCDC71L p.Pro162Leu Uncertain significance Single submitter
- CCDC71L p.Pro65His Uncertain significance Single submitter
- CCDC71L p.Ser198Arg Uncertain significance Single submitter
- CCDC71L p.Ser198Thr Uncertain significance Single submitter
- CCDC71L p.Thr116Ile Uncertain significance Single submitter
- CCDC71L p.Thr116Lys Uncertain significance Single submitter
- CCDC71L p.Thr187Arg Uncertain significance Single submitter
- CCDC71L p.Thr18Met Uncertain significance Single submitter
- CCDC71L p.Thr18Pro Uncertain significance Single submitter
-
CCDC71L p.Ser160Arg
Uncertain significance
No assertion criteria
breast ductal adenocarcinoma
Predictors split 4
The independent predictors disagree with each other — read with care.
All CCDC71L variants
Uncertain significance 61
- p.Ala117Thr Single submitter ⚠
- p.Ala121Glu Single submitter ⚠
- p.Ala121Gly Single submitter ⚠
- p.Ala129Thr Single submitter ⚠
- p.Ala137Thr Single submitter ⚠
- p.Ala139Val Single submitter ⚠
- p.Ala142Ser Single submitter ⚠
- p.Ala142Thr Single submitter ⚠
- p.Ala15Gly Single submitter ⚠
- p.Ala15Pro Single submitter ⚠
- p.Ala163Val Single submitter ⚠
- p.Ala167Ser Single submitter ⚠
- p.Ala213Pro Single submitter ⚠
- p.Ala59Ser Single submitter ⚠
- p.Arg118His Single submitter ⚠
- p.Arg123Trp Single submitter ⚠
- p.Arg138Gln Single submitter ⚠
- p.Arg143Ser Single submitter ⚠
- p.Arg148Gln Single submitter ⚠
- p.Arg204Pro Single submitter ⚠
- p.Arg211His Single submitter ⚠
- p.Arg212Lys Single submitter ⚠
- p.Arg212Ser Single submitter ⚠
- p.Arg212Thr Single submitter ⚠
- p.Arg214Cys Single submitter ⚠
- p.Arg21Gln Single submitter ⚠
- p.Arg234Gln Single submitter ⚠
- p.Arg66Cys Single submitter ⚠
- p.Arg66His Single submitter ⚠
- p.Asp110Asn Single submitter ⚠
- p.Asp110Glu Single submitter ⚠
- p.Asp199Asn Single submitter ⚠
- p.Gln215Lys Single submitter ⚠
- p.Glu203Gln Single submitter ⚠
- p.Gly173Arg Single submitter ⚠
- p.Gly30Arg Single submitter ⚠
- p.Gly32Arg Single submitter ⚠
- p.Leu56Pro Single submitter ⚠
- p.Lys85Arg Single submitter ⚠
- p.Met224Ile Single submitter ⚠
- p.Phe172Leu Single submitter ⚠
- p.Phe25Leu Single submitter ⚠
- p.Pro112Ala Single submitter ⚠
- p.Pro114Ser Single submitter ⚠
- p.Pro13Leu Single submitter ⚠
- p.Pro151Ser Single submitter ⚠
- p.Pro153Leu Single submitter ⚠
- p.Pro156Leu Single submitter ⚠
- p.Pro156Thr Single submitter ⚠
- p.Pro162Ala Single submitter ⚠
- p.Pro162Leu Single submitter ⚠
- p.Pro65His Single submitter ⚠
- p.Ser198Arg Single submitter ⚠
- p.Ser198Thr Single submitter ⚠
- p.Thr116Ile Single submitter ⚠
- p.Thr116Lys Single submitter ⚠
- p.Thr187Arg Single submitter ⚠
- p.Thr18Met Single submitter ⚠
- p.Thr18Pro Single submitter ⚠
- p.Trp201Arg Single submitter ⚠
- p.Ser160Arg No assertion criteria breast ductal adenocarcinoma ⚠